Horm Metab Res 1980; 12(8): 385-389
DOI: 10.1055/s-2007-996298
© Georg Thieme Verlag, Stuttgart · New York

Elevated Plasma and Tissue Concentrations of β-Endorphin and β-Lipotropin Associated with an Ectopic ACTH-Producing Lung Tumor

G. Kleber, V. Höllt, W. Oelkers, H. J. Quabbe
  • Abteilung für Neuropharmakologie, Max-Planck-Institut für Psychiatrie, München, and Endokrinologische Abteilung, Medizinische Klinik, Klinikum Steglitz, Freie Universität Berlin, Berlin, Germany
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Publication Date:
22 April 2008 (online)


β-Endorphin- and ACTH-like immunoreactive peptides were measured in plasma and certain tissues of a patient suffering from an oat-cell-carcinoma of the lungs and Cushing's syndrome. Using sensitive radioimmunoassays in combination with gel-filtration, highly elevated levels of β-endorphin, β-lipotropin (β-LPH), α-melanotropin (α-MSH) and ACTH were found.