Int J Sports Med 1985; 06(3): 136-138
DOI: 10.1055/s-2008-1025826
© Georg Thieme Verlag Stuttgart · New York

Hemorrheology of Marathon Running

G. Galea, R. J. L. Davidson
  • Haematology Unit, Department of Pathology, University of Aberdeen Medical School, Foresterhill, Aberdeen
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Publication History

Publication Date:
14 March 2008 (online)


The hemorheological effects of severe exertion were evaluated in eight males and six females before and after a marathon. A highly significant fall in red cell filterability (RCF) was accompanied by a significant rise in plasma osmolality. This correlation was further studied by a series of in vitro experiments to establish a cause-effect relationship. As plasma osmolality increased, RCF progressively diminished. These observations demonstrate that plasma hyperosmolality is an important etiological factor in reducing RCF during strenuous exercise.