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Neuropediatrics 1994; 25(5): 255-258
DOI: 10.1055/s-2008-1073031
DOI: 10.1055/s-2008-1073031
Short communication
© Georg Thieme Verlag KG Stuttgart · New York
Hypometabolism and Dipole Localization in Hemimegalencephaly: A Case Report
Further Information
Publication History
Publication Date:
19 March 2008 (online)
Abstract
A case of hemimegalencephaly was studied by means of neuroimaging (CT, MRI and PET) and magnetoencephalography (MEG). Hemimegalencephaly (HM) is a neuronal migration disorder. This is the first report of evaluation of HM with the use of PET and MEG from not only the morphological but also the functional point of view. PET with 11C-glucose showed a low radioactive concentration in the affected hemisphere, which suggested a metabolic deficit. MEG proved the epileptic foci existed mainly in the affected hemisphere, especially around a heterotopia and the pachygyric cortex, which was disclosed on MRI.
Key words
Hemimegalencephaly - PET - MRI - Magnetoencephalography - Infantile spasms