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CC BY 4.0 · Aorta (Stamford) 2016; 04(01): 25-28
DOI: 10.12945/j.aorta.2015.15.009
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Complete Resolution of Wegener’s Granulomatosis Lung Granuloma After Aortic Root Replacement

Sarah-Jayne Edmondson
1   Royal Brompton Hospital NHS Foundation Trust, Department of Cardiothoracic Surgery, London, UK
,
Saina Attaran
1   Royal Brompton Hospital NHS Foundation Trust, Department of Cardiothoracic Surgery, London, UK
,
Ulrich P. Rosendahl
1   Royal Brompton Hospital NHS Foundation Trust, Department of Cardiothoracic Surgery, London, UK
› Author Affiliations
Further Information

Publication History

22 March 2015

19 October 2015

Publication Date:
24 September 2018 (online)

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Abstract

Wegner’s granulomatosis (WG) is an autoimmune systemic vasculitis that results in necrotizing granulomas. We report a WG patient with a lung granuloma and aortic root dilatation, who underwent aortic root replacement on cardiopulmonary bypass (CPB). Intraoperatively, the patient suffered an aortic dissection, which was repaired immediately under deep hypothermic circulatory arrest (DHCA). Follow-up imaging showed complete granuloma resolution, despite absence of immunosuppressive therapy. Immune stimulation following CPB is well described; here, the opposite was observed and DHCA effects are discussed.

Key Words

Aortic root - Dissection - Inflammation - Wegener’s granulomatosis
 

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