Influenza-Ausbruch bei Aufzuchtferkeln unter Beteiligung von Mycoplasma hyorhinis und Haemophilus parasuis

Christine Unterweger; Bettina Wöchtl; Joachim Spergser; Rene Brunthaler; Matthias Untersperger; Kathrin Lillie-Jaschniski; Ralf Dürrwald; Isabel Hennig-Pauka

doi:10.15653/TPG-160100

Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere, Table of Contents

Tierarztl Prax Ausg G Grosstiere Nutztiere 2016; 44(04): 259-265
DOI: 10.15653/TPG-160100

Kasuistik

Schattauer GmbH

Influenza-Ausbruch bei Aufzuchtferkeln unter Beteiligung von Mycoplasma hyorhinis und Haemophilus parasuis

Ein FallberichtInfluenza outbreak in weaners with involvement of Mycoplasma hyorhinis and Haemophilus parasuis A case report

Authors

Christine Unterweger

¹Universitätsklinik für Schweine, Veterinärmedizinische Universität Wien, Österreich
Bettina Wöchtl

¹Universitätsklinik für Schweine, Veterinärmedizinische Universität Wien, Österreich
Joachim Spergser

²Institut für Mikrobiologie, Veterinärmedizinische Universität Wien, Österreich
Rene Brunthaler

³Institut für Pathologie, Veterinärmedizinische Universität Wien, Österreich
Matthias Untersperger

⁴Tierarztpraxis Untersperger, Bad Hall, Österreich
Kathrin Lillie-Jaschniski

⁵IDT Biologika GmbH, Dessau-Rosslau, Deutschland
Ralf Dürrwald

⁵IDT Biologika GmbH, Dessau-Rosslau, Deutschland
Isabel Hennig-Pauka

¹Universitätsklinik für Schweine, Veterinärmedizinische Universität Wien, Österreich

Abstract

Zusammenfassung

In einem geschlossenen Ferkelerzeugerbetrieb erkrankten etwa 80% der 7 Wochen alten Ferkel in der Aufzucht an einer fieberhaften Atemwegsinfektion mit einer Letalität von 5%. Neben eitrigen Broncho - pneumonien in Kombination mit interstitiellen Pneumonien insbesondere im Spitzen- und Mittellappenbereich lagen fibrinöse Serositiden in der Brust- und Bauchhöhle vor. Weiterführend gelang der Nachweis des nichtpandemischen Stamms von porzinem Influenza-A-Virus (FLUAVsw) Subtyp H1_avN1. Die molekulargenetischen Untersuchungen auf Mycoplasma (M.) hyopneumoniae und PRRSV verliefen negativ, doch konnten M. hyorhinis und Haemophilus parasuis aus serösen Häuten nach - gewiesen werden. Die möglicherweise unterschätzte Bedeutung von M. hyorhinis als Kofaktor bei Virusinfektionen und Verursacher von Spitzenlappenpneumonien wird hervorgehoben und aufgezeigt. Die Muttersauen des Bestands waren mit einem Influenzaimpfstoff geimpft worden, der den Subtyp H1_avN1 abdeckt. Nur 33% der untersuchten Ferkel hatten in der 7. Lebenswoche noch maternale Anti körper. Die Schwierigkeit einer Prophylaxe von Erkrankungen durch FLUAVsw bei Ferkeln mit nachlassender maternaler Immunität wird deutlich, wenn Impfstoffe erst ab dem 56. Lebenstag eingesetzt werden dürfen.

Summary

In a closed farrow-to-finish piglet producing farm 80% of 7-week-old piglets displayed respiratory disease with a 5% mortality rate. In addition to purulent bronchopneumonia in combination with interstitial pneumonia predominantly in the apical and middle lobes, fibrinous sero sitis was present in the thoracic and abdominal cavities. Further in vestigations succeeded in confirming the non-pandemic strain of porcine influenza A virus (FLUAVsw) subtype H1_avN1. The molecular genetic studies on Mycoplasma (M.) hyopneumoniae and porcine reproductive and respiratory syndrome virus were negative, whereas M. hyorhinis and Haemophilus parasuis were isolated from serous membranes. The possible importance of the underrated M. hyorhinis as a cofactor for viral infections should be emphasized and we de - monstrated that the cause of apical lobe pneumonia is not restricted to M. hyopneumoniae. Mother pigs had been vaccinated with an influenza vaccine covering the subtype H1_avN1. Only 33% of the exa - mined piglets had maternal antibodies in the 7th week of life. The difficulty of prophylaxis of infections by FLUAVsw in weaners due to lack of vaccine authorization for piglets before their 56th day is reflected by this observation.

Schlüsselwörter

Atemwegserkrankung - Läuferschweine - nichtpandemisches H1_avN1 - Impfung - maternale Antikörper

Keywords

Respiratory disease - weaners - non pandemic H1_avN1 infection - vaccination - maternal antibodies

Full Text

References

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