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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2018; 76(03): 163-169
DOI: 10.1590/0004-282X20180006
Article

Normative values of the Brief Repeatable Battery of Neuropsychological Tests in a Brazilian population sample: discrete and regression–based norms

Valores normativos da Brief Repeatable Battery of Neuropsychological Tests (BRB–N) em uma amostra da população Brasileira: dados discretos e contínuos

Authors

  • Alfredo Damasceno

    1   Universidade de Campinas, Departamento de Neurologia, Campinas SP, Brasil

  • Juliana Machado Santiago dos Santos Amaral

    2   Universidade Federal de Minas Gerais, Centro de Investigação em Esclerose Múltipla, Belo Horizonte MG, Brasil

  • Amilton Antunes Barreira

    3   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Hospital das Clínicas de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil

  • Jefferson Becker

    4   Hospital São Lucas, Serviço de Neurologia, Porto Alegre RS, Brasil
    5   Hospital São Lucas, Serviço de Neurologia, Porto Alegre RS, Brasil

  • Dagoberto Callegaro

    6   Universidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil

  • Kenia Repiso Campanholo

    6   Universidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil

  • Luciana Azevedo Damasceno

    7   Universidade Federal Fluminense, Departamento de Neurologia, Niterói RJ, Brasil

  • Denise Sisterolli Diniz

    8   Universidade Federal de Goiás, Hospital das Clínicas, Departamento de Neurologia, Goiânia GO, Brasil

  • Yara Dadalti Fragoso

    9   Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil

  • Paula S Franco

    9   Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil

  • Alessandro Finkelsztejn

    10   Hospital das Clínicas de Porto Alegre, Departamento de Neurologia, Porto Alegre RS, Brasil

  • Frederico M H Jorge

    6   Universidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil

  • Marco Aurélio Lana-Peixoto

    2   Universidade Federal de Minas Gerais, Centro de Investigação em Esclerose Múltipla, Belo Horizonte MG, Brasil

  • Andre Palma da Cunha Matta

    7   Universidade Federal Fluminense, Departamento de Neurologia, Niterói RJ, Brasil

  • Andréia Costa Rabelo Mendonça

    8   Universidade Federal de Goiás, Hospital das Clínicas, Departamento de Neurologia, Goiânia GO, Brasil

  • Janaína Noal

    10   Hospital das Clínicas de Porto Alegre, Departamento de Neurologia, Porto Alegre RS, Brasil

  • Renata Alves Paes

    11   Universidade Federal do Estado do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil

  • Regina Maria Papais-Alvarenga

    11   Universidade Federal do Estado do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil

  • Adriana Gutterres Pereira

    4   Hospital São Lucas, Serviço de Neurologia, Porto Alegre RS, Brasil

  • Carina Tellaroli Spedo

    3   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Hospital das Clínicas de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil

  • Benito Pereira Damasceno

    1   Universidade de Campinas, Departamento de Neurologia, Campinas SP, Brasil

This work was partially supported by Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) (postdoctoral grant number 2016/04270–0).
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ABSTRACT

Objective Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB–N) was developed to assess cognitive functions most–frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB–N in a Brazilian population sample.

Methods We recruited 285 healthy individuals from the community at 10 Brazilian sites and applied the BRB–N version A in 237 participants and version B in 48 participants. Continuous norms were calculated with multiple–regression analysis.

Results Mean raw scores and the 5th percentile for each neuropsychological measure are provided, stratified by age and educational level. Healthy participants' raw scores were converted to scaled scores, which were regressed on age, sex and education, yielding equations that can be used to calculate predicted scores.

Conclusion Our normative data allow a more widespread use of the BRB–N in clinical practice and research.

RESUMO

Objetivo Disfunção cognitiva é comum em pacientes com esclerose múltipla. Por isto, a Brief Repeatable Battery of Neuropsychological Tests (BRB–N) foi desenvolvida para avaliar as funções cognitivas mais frequentemente alteradas na doença. Entretanto, estão faltando dados normativos desta bateria no Brasil. Assim, nosso objetivo foi fornecer valores normativos contínuos e discretos da BRB–N para a população brasileira.

Métodos Foram recrutados 285 indivíduos sadios da comunidade em 10 centros do Brasil e aplicada a versão A em 237 e a versão B em 48 sujeitos. Normas contínuas foram calculadas com análise de regressão múltipla.

Resultados Escores brutos médios e 5°percentil para cada subteste são fornecidos, estratificados por idade e nível educacional. Os escores brutos dos sujeitos sadios foram convertidos em escores de escalas e postos em regressão quanto a idade, sexo e educação, fornecendo equações que podem ser usadas para calcular escores previsíveis.

Conclusão Nossos dados normativos permitem um uso mais amplo da BRB–N na prática clínica e na pesquisa, fornecendo normas para dados discretos e contínuos. Normas para dados discretos deveriam ser usadas com cuidado e escores demograficamente ajustados são geralmente preferidos quando interpretando dados neuropsicológicos.

Keywords

cognition - multiple sclerosis - neuropsychology

Palavras-chave

cognição - esclerose múltipla - neuropsicologia

Support

This work was partially supported by Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) (postdoctoral grant number 2016/04270–0).




Publication History

Received: 16 September 2017

Accepted: 12 December 2017

Article published online:
28 August 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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