Non-syndromic Keratocystic Odontogenic Tumor Involving the Maxillary Sinus: Case Report

Summary

Introduction: The odontogenic keratocyst tumor is rarely found in maxilla.

Case Report: This article describes a report of a case of a 60-year-old Caucasian female with an asymptomatic growth in the region of the posterior maxilla tumor diagnosed as odontogenic keratocyst. We discuss the diagnosis and workup for this type of injury.

Resumo

Introdução: O tumor odontogênico queratocístico é raramente encontrado em maxilla.

Relato do Caso: Este artigo descreve o relato de um caso de uma paciente de 60 anos de idade, leucoderma, sexo feminino, com um crescimento assintomático na região de maxila posterior diagnosticada como tumor odontogênico queratocístico. Também é discutido o diagnóstico e a propedêutica para este tipo de lesão.

Keywords

odontogenic tumors - maxillary sinus - radiology - surgery

Palavras-chave

tumores odontogênicos - seio maxilar - radiologia - cirurgia

• Bibliographical References

• 1 Shear M, Speight PM , editors. Cysts of the oral and maxillofacial regions. Oxford: Blackwell; 2007. p. 6-59
• 2 Philipsen HP. Keratocystic odontogenic tumour. In: Barnes L, Eveson JW, Reichart P, Sidransky D, , editors. World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005. . p. 306-7
• 3 Ide F, Obara K, Yamada H, Mishima K, Saito I, Horie N, Shimoyama T, Kusama K. Hamartomatous proliferatinons of odontogenic epithelium within the jaws: a potential histogenic source of intraosseous epithelial odontogenic tumors. J Oral Pathol Med 2007; 36 (4) 229-35
• 4 Gomez RS, De Marco L. Possible molecular approach to the treatment of odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99 (5) 527-8
• 5 Myoung H, Hong SP, Hong SD, Lee JI, Lim CY, Choung PH, Lee JH, Choi JY, Seo BM, Kim MJ. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91 (3) 328-33
• 6 Press SG. Odontogenic tumors of the maxillary sinus. Curr Opin Otolaryngol Head Neck Surg 2008; 16 (1) 47-54
• 7 González-Alva P, Tanaka A, Oku Y, Yoshizawa D, Itoh S, Sakashita H, Ide F, Tajima Y, Kusama K. Keratocystic odontogenic tumor: a retrospective study of 183 cases. J Oral Sci 2008; 50 (2) 205-12
• 8 Regezi JA. Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Mod Pathol 2002; 15 (3) 331-41
• 9 Brannon RB. The odontogenic keratocyst. A clinico pathologic study of 312 cases. Part I. Clinical features. Oral Surg Oral Med Oral Pathol 1976; 42 (1) 54-72
• 10 Damm DD. Dome-like radiodensity of the maxillary sinus. Odontogenic keratocyst. Gen Dent 2008; 56 (7) 761-63
• 11 Absi EG, Sim RL. Odontogenic keratocyst involving the maxillary sinus: report of two cases. Dentomaxillofac Radiol 1994; 23 (4) 226-9
• 12 Vencio EF, Mota A, de Melo Pinho C, Dias Filho AA. Odontogenic keratocyst in maxillary sinus with invasive behaviour. J Oral Pathol Med 2006; 35 (4) 249-51
• 13 Barreto DC, Gomez RS, Bale AE, Boson WL, De Marco L. PTCH gene mutations in odontogenic keratocysts. J Dent Res 2000; 79 (6) 1418-22
• 14 Sun LS, Li XF, Li TJ. PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. J Dent Res 2008; 87 (6) 575-9
• 15 Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J. Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13. J Invest Dermatol 2005; 124 (3) 536-44
• 16 Heikinheimo K, Jee KJ, Morgan PR, Nagy B, Knuutila S, Leivo I. Genetic changes in sporadic keratocystic odontogenic tumors (odontogenic keratocysts). J Dent Res 2007; 86 (6) 544-9
• 17 Malciæ A, Jukiæ S, Aniæ I, Paveliæ B, Kapitanoviæ S, Kruslin B, Paveliæ K. Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst. J Oral Pathol Med 2008; 37 (5) 294-301
• 18 González-Moles MA, Mosqueda-Taylor A, Delgado-Rodríguez M, Martínez-Mata G, Gil-Montoya JA, Díaz-Franco MA, Bravo-Pérez JJ, M-González N. Analysis of p53 protein by PAb240, Ki-67 expression and human papillomavirus DNA detection in different types of odontogenic keratocyst. Anticancer Res 2006; 26 (1A): 175-81
• 19 Bsoul SA, Paquette M, Terezhalmy GT, Moore WS. Odontogenic keratocyst. Quintessence Int 2002; 33 (5) 400-1
• 20 Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005; 63 (5) 635-9