CC BY-NC-ND 4.0 · Indian J Plast Surg 2016; 49(02): 268-270
DOI: 10.4103/0970-0358.191307
Case Report
Association of Plastic Surgeons of India

Successful penile reconstruction following prior arteriovenous loop thrombosis due to undiagnosed protein-S deficiency and exogenous testosterone

Parameswaran Anoop
Department of Hematology, Apollo Hospitals, Bengaluru, Karnataka, India
,
Vithal Malmande
1   Department of Plastic Surgery, Apollo Hospitals, Bengaluru, Karnataka, India
,
M. N. Prakash Kumar
1   Department of Plastic Surgery, Apollo Hospitals, Bengaluru, Karnataka, India
,
Naveen Rao
1   Department of Plastic Surgery, Apollo Hospitals, Bengaluru, Karnataka, India
› Author Affiliations
Further Information

Publication History

Publication Date:
13 August 2019 (online)

ABSTRACT

Flap failure from microvascular thrombotic occlusion is a rare but significant cause for unsuccessful reconstructive surgery. We encountered thrombosis of arteriovenous loop in a patient undergoing phallus reconstruction. Further investigations revealed underlying previously asymptomatic hypercoagulable state due to protein-S deficiency in addition to long-term exogenous testosterone administration. Role of thrombophilia testing, thrombogenic potential of testosterone and the need for therapeutic perioperative anti-coagulation in such situations are described here.

 
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