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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2016; 26(01): 73-80
DOI: 10.4103/0971-3026.178340
Intervention Radiology

Outcomes of catheter-directed treatment of lower extremity deep vein thrombosis of patients presenting to a tertiary care hospital

Gaurav Sundar
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Shyamkumar N Keshava
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Vinu Moses
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
George K Chiramel
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Munawwar Ahmed
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Suraj Mammen
Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
Sunil Aggarwal
Department of Vascular Surgery, Christian Medical College, Vellore, Tamil Nadu, India
,
Edwin Stephen
Department of Vascular Surgery, Christian Medical College, Vellore, Tamil Nadu, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Background: Lower extremity deep vein thrombosis (DVT) is a common illness with an annual incidence of 1 per 1000 adults. The major long-term complication of DVT is post-thrombotic syndrome (PTS) which occurs in up to 60% of patients within 2 years of an episode of DVT. Aims: We aim to evaluate the outcomes of catheter-directed treatment (CDT) for symptomatic acute or subacute lower extremity DVT. Materials and Methods: A retrospective 12-year study was conducted on the outcomes of CDT on 54 consecutive patients who presented with acute or subacute lower extremity DVT to our hospital. Statistical Analysis: Descriptive summary statistics and the Chi-square test were used to measure the outcomes of CDT. Results: Grade 3 thrombolysis was achieved in 25 (46.3%) patients, grade 2 thrombolysis in 25 (46.3%) patients, and grade 1 thrombolysis in 4 (7.4%) patients. Significant recanalization (grade 2 or 3 thrombolysis) was possible in 50 (92.6%) patients. There was no statistically significant difference in the percentage of significant recanalization that could be achieved between patients who underwent CDT before and after 10 days. There was no significant difference between the thrombolysis achieved between urokinase and r-tPA. PTS was seen in 33% of the patients. Major complications were seen in 5.5% of the patients. Conclusion: CDT is a safe and effective therapeutic technique in patients with acute and subacute lower extremity DVT, if appropriate patient selection is made.

Keywords

Catheter-directed treatment - deep vein thrombosis - thrombolysis


Publication History

Article published online:
30 July 2021

© 2016. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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