CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2009; 19(03): 248-251
DOI: 10.4103/0971-3026.54876
Obsetric Imaging

Sonological appearance of idiopathic arterial calcification in fetus: A rare case

BR Nagaraj
Department of Radio Diagnosis, Bangalore Medical College and Research Institute, Bangalore, India
,
Prakash Jain
Department of Radio Diagnosis, Bangalore Medical College and Research Institute, Bangalore, India
,
Deepu Alex Thomas
Department of Radio Diagnosis, Bangalore Medical College and Research Institute, Bangalore, India
,
M Raghu
Department of Radio Diagnosis, Bangalore Medical College and Research Institute, Bangalore, India
› Author Affiliations

Abstract

Idiopathic arterial calcification (IAC) is a rare disease characterized by extensive arterial wall calcification. This condition is almost always fatal. A total of 162 cases have been reported to date, with most cases diagnosed postnatally and less than 13 cases having been suspected antenatally. This case report describes a case of IAC detected antenatally with USG at 28 weeks′ gestation.



Publication History

Article published online:
02 August 2021

© 2009. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Bird T. Idiopathic arterial calcification in infancy. Arch Dis Child 1974;49:82-9.
  • 2 Rosenbaum DM, Blumhagen JD. Sonographic recognition of idiopathic arterial calcification of infancy. AJR Am J Roentgenol 1986;146:249-50.
  • 3 Eronen M, Pohjavuori M, Heikkila P. Fatal outcome of 2 siblings with idiopathic arterial calcification of infancy diagnosed in utero. Pediatr Cardiol 2001;22:167-9.
  • 4 Glatz AC, Pawel BR, Hsu DT, Weinberg P, Chrisant MR. Idiopathic infantile arterial calcification: Two case reports, a review of the literature and a role for cardiac transplantation. Pediatr Transplant 2006;10:225-33.
  • 5 Chong C, Hutchins G. Idiopathic Infantile Arterial Calcification: The Spectrum of Clinical Presentations. Pediatr Dev Pathol 2007 Aug 23:1.
  • 6 Nagar AM, Hanchate V, Tandon A, Thakkar H, Chaubal NG. Antenatal Detection of Idiopathic Arterial Calcification With Hydrops Fetalis. J Ultrasound Med 2003;22: 653-9.
  • 7 Bellah RD, Zawodniak L, Librizzi RJ, Harris MC. Idiopathic arterial calcification of infancy: prenatal and postnatal effects of therapy in an infant. J Pediatr 1992;121:930-3.
  • 8 Bryant JH, White WA. A case of calcification of the arteries and obliterative endarteritis associated with hydronephrosis in a child aged 6 months. Guys Hosp Rep 1901;55:17-28.
  • 9 Rutsch F, Ruf N, Vaingankar S, Toliat MR, Suk A, Hφhne W, et al . Mutations in ENPP1 are associated with ′idiopathic′ infantile arterial calcification: Nat Genet 2003;34:379-81.
  • 10 Numakura C, Yamada M, Ariyasu D, Maesaka A, Kobayashi H, Nishimura G, et al . Genetic and enzymatic analysis for two Japanese patients with idiopathic infantile arterial calcification. J Bone Miner Metab 2006;24:48-52.
  • 11 Pashankar D, Moore L. Test and teach. Number eighty three: Part 1. Idiopathic arterial calcification of infancy. Pathology 1997;29:175,217.
  • 12 Saigal G, Azouz EM The spectrum of radiologic findings in idiopathic arterial calcification of infancy: pictorial essay. Can Assoc Radiol J 2004;55:102-7
  • 13 Stuart G, Wren C, Bain H. Idiopathic infantile arterial calcification in two siblings: failure of treatment with diphosphonate. Br Heart J 1990;64:156-9.
  • 14 Spear R, Mack LA, Benedetti TJ, Cole RE. Idiopathic infantile arterial calcification: in utero diagnosis. J Ultrasound Med 1990;9:473-6.
  • 15 Samon LM, Ash KM, Murdison KA. Aorto-pulmonary calcification: an unusual manifestation of idiopathic calcification of infancy evident antenatally. Obstet Gynecol 1995;85:863-5.
  • 16 Levine JC, Campbell J, Nadel A. Prenatal diagnosis of idiopathic infantile arterial calcification. Circulation 2001;103:325-6.
  • 17 Ciana G, Trappan A, Bembi B, Benettoni A, Maso G, Zennaro F, et al . Generalized arterial calcification of infancy: Two siblings with prolonged survival. Eur J Pediatr 2006;165:258-63.
  • 18 Ramjan KA, Roscioli T, Rutsch F, Sillence D, Munns CF. Generalized arterial calcification of infancy: Treatment with bisphosphonates. Nat Clin Pract Endocrinol Metab 2009;5:167-72.