Subscribe to RSS

DOI: 10.4103/0971-5851.116197
A diagnostic dilemma in a patient with lymphoma

Abstract
We report the case of a 49-year-old man with a diagnosis of gastric diffuse large B cell non-Hodgkin′s lymphoma, treated with two lines of chemotherapy followed by radiotherapy, and presented about 3 months after completing therapy with recurrent episodes of epigastric pain, gastrointestinal (GI) bleeding. Computed tomography scan, positron emission tomography scan, and upper GI endoscopy revealed gastric wall thickening and lymphadenopathy. Biopsy and histopathology ultimately revealed Strongyloides stercoralis infection that was mimicking disease recurrence. Opportunistic parasitic infections represent one of the major challenges in the management of cancer patients.
Publication History
Article published online:
20 July 2021
© 2013. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Koch P, Del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, et al. Primary gastrointestinal non-Hodgkin′s lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92. J Clin Oncol 2001;19:3861-73.
- 2 Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, et al. Soil-transmitted helminthes infections: Ascariasis, trichuriasis, and hookworm. Lancet 2006;367:1521-32.
- 3 Keiser PB, Nutman TB. Strongyloides stercoralis in the Immuno compromised Population. Clin Microbiol Rev 2004;17:208-17.
- 4 Husni RN, Gordon SM, Longworth DL, Adal KA. Disseminated Strongyloides stercoralis infection in an immunocompetent patient. Clin Infect Dis 1996;23:663.
- 5 Genta RM, Miles P, Fields K. Opportunistic Strongyloides stercoralis infection in lymphoma patients. Report of a case and review of the literature. Cancer 1989;63:1407-11.
- 6 Gotuzzo E, Terashima A, Alvarez H, Tello R, Infante R, Watts DM, et al. Strongyloides stercoralis hyper infection associated with human T cell lymph tropic virus type-1 infection in Peru. Am J Trop Med Hyg 1999;60:146-9.
- 7 Maguire JW. Intestinal nematodes (roundworms). In: Mandell GL, Bennett JE, Dolan R, editors. Mandell, Douglas, and Bennett′s Principles and Practice of Infectious Diseases. 7 th ed. Orlando, FO: Saunders Elsevier; 2009: chap. 287.
- 8 Salazar SA, Berk SH, Howe D, Berk SL. Ivermectin vs thiabendazole in the treatment of strongyloidiasis. Infect Med 1994:50-9.
- 9 Liu LX, Weller PF Strongyloidiasis and other intestinal nematode infections. Infect Dis Clin North Am 1993;7:655-82.