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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2016; 37(03): 207-208
DOI: 10.4103/0971-5851.190361
LETTERS TO EDITOR

Subacute quadriplegic myelopathy following intrathecal methotrexate

Boby Varkey Maramattom
Department of Neurology, Aster Medcity, Cheranelloor, Kochi, Kerala, India
,
Sandeep Padmanabhan
Department of Neurology, Aster Medcity, Cheranelloor, Kochi, Kerala, India
,
Vivek Radhakrishnan
Department of Medical Oncology, Aster Medcity, Cheranelloor, Kochi, Kerala, India
› Author Affiliations Financial support and sponsorship Nil.
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Publication History

Article published online:
12 July 2021

© 2016. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Bleyer A, Choi M, Wang SJ, Fuller CD, Raney RB. Increased vulnerability of the spinal cord to radiation or intrathecal chemotherapy during adolescence: A report from the Children's Oncology Group. Pediatr Blood Cancer 2009;53:1205-10.
  • 2 Cachia D, Kamiya-Matsuoka C, Pinnix CC, Chi L, Kantarjian HM, Cortes JE, et al. Myelopathy following intrathecal chemotherapy in adults: A single institution experience. J Neurooncol 2015;122:391-8.
  • 3 Pascual AM, Coret F, Casanova B, Láinez MJ. Anterior lumbosacral polyradiculopathy after intrathecal administration of methotrexate. J Neurol Sci 2008;267:158-61.
  • 4 Shintaku M, Toyooka N, Koyama T, Teraoka S, Tsudo M. Methotrexate myelopathy with extensive transverse necrosis: Report of an autopsy case. Neuropathology 2014;34:547-53.
  • 5 Sherman PM, Belden CJ, Nelson DA. Magnetic resonance imaging findings in a case of cytarabine-induced myelopathy. Mil Med 2002;167:157-60.
  • 6 Linnebank M, Moskau S, Jürgens A, Simon M, Semmler A, Orlopp K, et al. Association of genetic variants of methionine metabolism with methotrexate-induced CNS white matter changes in patients with primary CNS lymphoma. Neuro Oncol 2009;11:2-8.
  • 7 Ackermann R, Semmler A, Maurer GD, Hattingen E, Fornoff F, Steinbach JP, et al. Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites. J Neurooncol 2010;97:425-7.