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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2011; 32(04): 211-213
DOI: 10.4103/0971-5851.95143
CASE REPORT

Isolated cerebellar involvement in posterior reversible encephalopathy syndrome in a child with acute lymphoblastic leukemia

Authors

  • Narendra Chaudhary

    Department of Pediatrics, Kasturba Medical College, Manipal University, Manipal, Karnataka, India

  • Rubeena Majeed

    Department of Radiodiagnosis, Kasturba Medical College, Manipal University, Manipal, Karnataka, India

  • Anupama Borker

    Department of Pediatrics, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
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Abstract

Parieto-occipital region is the most commonly involved site in posterior reversible encephalopathy syndrome (PRES). Cerebellar involvement has been reported with the predominant involvement of posterior cerebral regions, but isolated cerebellar involvement in PRES has been reported only once in English literature. We report here a 7-year-old boy with acute lymphoblastic leukemia who had PRES with isolated cerebellar involvement during induction chemotherapy. He presented with sudden onset headache, vomiting and hypertension followed by seizures, unconsciousness, and involuntary movements. Computed tomography scan revealed bilateral cerebellar hypodensities. He improved within few hours and reversibility of the lesions was documented on magnetic resonance imaging after 2 weeks. Awareness of atypical patterns in distribution of imaging abnormalities is important to recognize PRES more accurately and to avoid unnecessary diagnostic procedures and treatment.

Keywords

Isolated cerebellar involvement - posterior reversible encephalopathy - reversible occipito-parietal leukoencephalopathy


Publication History

Article published online:
06 August 2021

© 2011. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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