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CC BY-NC-ND 4.0 · J Lab Physicians 2013; 5(01): 51-54
DOI: 10.4103/0974-2727.115935
Original Article

Association of Secondary Hyperparathyroidism with Hemoglobin Level in Patients with Chronic Kidney Disease

Happy Chutia
Department of Biochemistry, North East Indira Gandhi Institute of Health and Medical Science, Shillong, Meghalaya, India
,
Alice Abraham Ruram
Department of Biochemistry, North East Indira Gandhi Institute of Health and Medical Science, Shillong, Meghalaya, India
,
Himashree Bhattacharyya
Department of Community Medicine, North East Indira Gandhi Institute of Health and Medical Science, Shillong, Meghalaya, India
,
Polina Boruah
Department of Biochemistry, North East Indira Gandhi Institute of Health and Medical Science, Shillong, Meghalaya, India
,
Chandan Nath
Department of Biochemistry, North East Indira Gandhi Institute of Health and Medical Science, Shillong, Meghalaya, India
› Author Affiliations Source of Support: Nil
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ABSTRACT

Purpose: Secondary hyperparathyroidism (SHPT) is one of the less recognized reasons of anemia in chronic kidney disease (CKD). In this study, we evaluated the role of SHPT as a cause of anemia and correlation of intact parathyroid hormone (iPTH) and hemoglobin (Hb) level in hemodialysis (HD) patients.

Methods: This cross-sectional study was carried out in 63 individuals admitted in HD unit of the institute. Serum samples were collected and urea, creatinine, Hb, ferritin and iPTH levels were measured. Statistical analysis was carried out using the SPSS software (IBM, NY, USA).

Results: Mean ± standard deviation for serum urea, creatinine, Hb, ferritin and intact PTH were 177 ± 15.52, 15.16 ± 2.28 mg/dl, 7.03 ± 2.26 g/dl, 654.7 ± 563.4 ng/ml, 539.18 ± 493.59 pg/ml respectively. A reverse correlation was found between intact PTH and Hb level.

Conclusions: A variety of postulated pathophysiological mechanisms linking SHPT and anemia in CKD are discussed. An efficient control of parathyroid hormone hypersecretion may be required to achieve a better management of anemia in HD patients.

Key words:

Anemia - chronic kidney disease - ferritin - hemoglobin - intact parathyroid hormone - secondary hyperparathyroidism


Publication History

Article published online:
07 April 2020

© 2013.

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