CC BY-NC-ND 4.0 · J Lab Physicians 2014; 6(02): 117-120
DOI: 10.4103/0974-2727.141511
Case Report

A Rare Case of Splenic Littoral Cell Angioma in a Child

Recep Bedir
Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey
,
İbrahim Şehitoğlu
Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey
,
Ahmet Salih Calapoğlu
Department of Pediatric Surgery, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey
,
Cüneyt Yurdakul
Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey
› Institutsangaben
Source of Support: Nil

ABSTRACT

Littoral cell angioma (LCA) is a rare, benign primary vascular neoplasm of the spleen. The tumor originates from the littoral cells lining the sinuses of the red pulp of the spleen. Preoperative distinction of this tumor from other benign or malign splenic lesions is difficult. Radiologically most cases present as multiple nodules. Definitive diagnosis can only be made histopathologically and immunohistochemically following splenectomy. This clinical situation can coexist with various malignancies and autoimmune disorders. Even though, it is mostly benign, since it has the potential to become malignant after splenectomy, long-term follow-up is required. We present an LCA case, which appeared as a solitary mass in the spleen of an 11-year-old girl with abdominal pain admitted to our hospital.



Publikationsverlauf

Artikel online veröffentlicht:
19. April 2020

© 2014.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • REFERENCES

  • 1 Falk S, Stutte HJ, Frizzera G. Littoral cell angioma. A novel splenic vascular lesion demonstrating histiocytic differentiation. Am J Surg Pathol 1991;15:1023-33.
  • 2 Ursuleac I, Iosif C, Bîrla R, Dobrea C, Gaman AM, Arsene D, et al. Littoral cell angioma of the spleen: A surprising cause of anemia. Rom J Morphol Embryol 2013;54:885-8.
  • 3 Matuszczak E, Reszec J, Debek W, Hermanowicz A, Chyczewski L. Is littoral cell angioma of the spleen as rare as previously believed in the pediatric population? Folia Histochem Cytobiol 2012;50:480-5.
  • 4 Wang YJ, Li F, Cao F, Sun JB, Liu JF, Wang YH. Littoral cell angioma of the spleen. Asian J Surg 2009;32:167-71.
  • 5 Harmon RL, Cerruto CA, Scheckner A. Littoral cell angioma: A case report and review. Curr Surg 2006;63:345-50.
  • 6 Emir S, Sozen S, Yazar MF, Altinsoy HB, Arslan Solmaz O, Ozkan Z. Littoral-cell angioma of the spleen. Arch Iran Med 2013;16:189-91.
  • 7 Hu ZQ, A YJ, Sun QM, Li W, Li L. The splenic Littoral cell angioma in China: A case report and review. World J Surg Oncol 2011;9:168.
  • 8 Ramdall RB, Alasio TM, Cai G, Yang GC. Primary vascular neoplasms unique to the spleen: Littoral cell angioma and splenic hamartoma diagnosis by fine-needle aspiration biopsy. Diagn Cytopathol 2007;35:137-42.
  • 9 Arber DA, Strickler JG, Chen YY, Weiss LM. Splenic vascular tumors: A histologic, immunophenotypic, and virologic study. Am J Surg Pathol 1997;21:827-35.
  • 10 Tatli S, Cizginer S, Wieczorek TJ, Ashley SW, Silverman SG. Solitary littoral cell angioma of the spleen: Computed tomography and magnetic resonance imaging features. J Comput Assist Tomogr 2008;32:772-5.
  • 11 Lin XY, Li JM, Wang QX, Feng JZ, Zhao MQ, Zhong WX, et al. Littoral cell angioma of the spleen: Report of three cases and a review of the literature. Chin Med J (Engl) 2011;124:3423-6.