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CC BY 4.0 · World J Nucl Med 2013; 12(01): 048-050
DOI: 10.4103/1450-1147.113966
Case Report

Excessive Hepatic Arterial-portal Venous Shunting May Predict Failure of Microparticle Localization in Hepatocellular Carcinomas

Autoren

  • Andrew Eik Hock Tan

    Department of Nuclear Medicine and PET, Singapore General Hospital, Outram, Singapore

  • Yung Hsiang Kao

    Department of Nuclear Medicine and PET, Singapore General Hospital, Outram, Singapore

  • Wanying Xie

    Department of Nuclear Medicine and PET, Singapore General Hospital, Outram, Singapore
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Abstract

Locoregional treatment of hepatocellular carcinomas using yttrium-90 (Y-90) microspheres is an emerging modality, and involves the administration of such radioactive particles directly into the hepatic arterial vasculature. We present the case of a 58-year-old gentleman undergoing evaluation for Y-90 microsphere therapy for hepatocellular carcinoma, in which our findings suggest that significant hepatic arterial portal venous shunting detected during the angiogram maybe a predictor of poor localization of microspheres in the turmor, and that centers that utilize body surface area (BSA) approaches for dosimetry should take note of such findings.

Keywords

Hepatocellular carcinoma - Y-90 microsphere therapy - arteria-portal venous shunting


Publikationsverlauf

Artikel online veröffentlicht:
14. August 2025

© 2013. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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