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CC BY-NC-ND 4.0 · World J Nucl Med 2014; 13(03): 149-153
DOI: 10.4103/1450-1147.144812
Original article

Comparison of the relative renal function calculated with 99mTc-diethylenetriaminepentaacetic acid and 99mTc-dimercaptosuccinic acid in children

Tanju Çelik
Department of Pediatrics, School of Medicine, Mustafa Kemal University, Antakya, Hatay
,
Hülya Yalçin
1   Department of Nuclear Medicine, School of Medicine, Mustafa Kemal University, Antakya, Hatay
,
Emel Günay
2   Department of Nuclear Medicine, School of Medicine, Mersin University, Mersin
,
Aynur Özen
3   Department of Nuclear Medicine, Bağcılar Hospital, Istanbul, Turkey
,
Cahit Özer
4   Department of Family Medicine, School of Medicine, Mustafa Kemal University, Antakya, Hatay
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The aim was to compare the relative renal functions measured with technetium-99m dimercaptosuccinic acid (99mTc-DMSA) and technetium-99m diethylenetriaminepentaacetic acid (99mTc-DTPA) in children with renal diseases. Relative renal function of 128 children who applied to three hospitals from 2009 to 2011 were analyzed retrospectively. The mean value measured with 99mTc-DTPA and 99mTc-DMSA were 51.58 ± 14.95 and 51.96 ± 14.99 for the right kidney, 47.87 ± 15.27 and 47.94 ± 15.17 for the left kidney, respectively. A significant positive correlation was found between the relative renal functions (r = 0.963, P < 0.001). In Bland-Altman plots, the mean difference between two methods was 0.7 and the correlation limits were between 10.1 and-10.8. As a result, although 99mTc-DMSA is accepted as the most reliable method for the determination of relative renal function, 99mTc-DTPA can be another choice for the calculation of relative renal function without a complementary DMSA scan particularly in pediatric patients who require renogram curve and GFR calculations.

Keywords

Child - relative renal function - technetium-99m diethylenetriaminepentaacetic acid - technetium-99m dimercaptosuccinic acid


Publication History

Article published online:
23 May 2022

© 2014. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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