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CC BY-NC-ND 4.0 · Asian J Neurosurg 2016; 11(04): 451
DOI: 10.4103/1793-5482.145352
CASE REPORT

Coexistent dysembryoplastic neuroepithelial tumour and pilocytic astrocytoma

Jitendra Nasit
Department of Pathology, Government Medical College and Sir Sayajirao General Hospital, Vadodara, Gujarat
,
Payal Shah
1   Department of Pathology, Pandit Deendayal Upadhyay Government Medical College and Hospital, Rajkot, Gujarat
,
Himanshu Zalawadia
2   Department of Radiodiagnosis, Rajkot Imaging Center, Rajkot, Gujarat
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Dysembryoplastic neuroepithelial tumour (DNET) is an uncommon mixed glioneuronal tumour. DNET is classified as Grade I neoplasm in revised World Health Organization classification of tumors of the nervous system. DNET is commonly seen in the temporal lobe of children and young adults with features of pharmacoresistant complex partial seizures. Tumors arising in association with DNETs are rare. Only two cases of pilocytic astrocytoma (PA) arising in DNETs are reported. Surgical excision is the only successful management with favourable prognosis. The development of recurrence and malignancy after subtotal or even after complete excision challenges the premise of stability and highlights the importance of close clinical follow up. Here, a case of DNET with area of PA is described which helps in understanding the pathogenesis and biological behavior of DNET.

Key-words:

Dysembryoplastic neuroepithelial tumour - malignant transformation - pilocytic astrocytoma - seizure


Publication History

Article published online:
20 September 2022

© 2016. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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