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CC BY-NC-ND 4.0 · Asian J Neurosurg 2016; 11(03): 319-320
DOI: 10.4103/1793-5482.149998
CASE REPORT

Glioblastoma with signet ring cell morphology: A diagnostic challenge

Naveen Krishnamoorthy
Department of Histopathology, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka
,
Vidya Veldore
1   Department of Research and Development, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka
,
P Sridhar
2   Department of Radiotherapy, HCG Bangalore Institute of Oncology, Sampangiram Nagar, Bengaluru, Karnataka
,
M Govindrajan
3   Department of Radiodiagnosis, HCG Bangalore Institute of Oncology, Sampangiram Nagar, Bengaluru, Karnataka
,
Shilpa Prabhudesai
Department of Histopathology, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka
,
Digantha Hazarika
Department of Histopathology, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka
,
B Ajaikumar
2   Department of Radiotherapy, HCG Bangalore Institute of Oncology, Sampangiram Nagar, Bengaluru, Karnataka
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Glioblastoma (WHO Grade IV), the most frequent malignant brain tumor, can have varied morphologic variations like epithelial/glandular structures, granular cells, and lipidized cells. Glioblastoma with signet ring cell morphology is very unusual and can mimic a metastatic carcinoma. These rare tumors may be just a morphological variant or may signify a different carcinogenic pathway.

Key-words:

Glioblastoma - signet ring morphology - mimic-metastatic carcinoma


Publication History

Article published online:
20 September 2022

© 2016. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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