CC BY-NC-ND 4.0 · Avicenna J Med 2012; 02(03): 74-76
DOI: 10.4103/2231-0770.102283
CASE REPORT

Myxoinflammatory fibroblastic sarcoma of the thigh: A morphologic diversity

Vanisri H Raghavan
Department of Pathology, JSS Medical College, JSS University, Mysore, Karnataka, India
,
Suchitha Satish
Department of Pathology, JSS Medical College, JSS University, Mysore, Karnataka, India
,
Sunila Ravishankar
Department of Pathology, JSS Medical College, JSS University, Mysore, Karnataka, India
,
Gubbanna V Manjunath
Department of Pathology, JSS Medical College, JSS University, Mysore, Karnataka, India
› Author Affiliations

Abstract

Myxoinflammatory fibroblastic sarcoma (MIFS)/acralmyxoinflammatory fibroblastic sarcoma (AMFS) is a rare, painless, low-grade neoplasm which commonly occurs in the extremities. It has a distinctive morphology and can be a diagnostic challenge, simulating inflammatory conditions as well as neoplastic conditions. They are low-grade sarcomas with a protracted clinical course, a high rate of local recurrence and a low rate of metastasis. We report a case of proximal MIFS in a 50-year-old woman who presented with a mass in the thigh.



Publication History

Article published online:
09 August 2021

© 2012. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 Khadilkar NP, Rao PS. Cytological diagnosis of myxoinflammatory fibroblastic sarcoma: A case report and discussion of differential diagnosis. Kathmandu Univ Med J (KUMJ) 2006;4:235-7.
  • 2 Meis-Kindblom JM, Kindblom LG. Acral myxoinflammatory fibroblastic sarcoma: A low-grade tumor of the hands and feet. Am J Surg Pathol 1998;22:911-24.
  • 3 Hassanein AM, Atkinson SP, Al-Quran SZ, Jain SM, Reith JD. Acral myxoinflammatory fibroblastic sarcoma: Are they all low-grade neoplasms? J Cutan Pathol 2008;35:186-91.
  • 4 Montgomery EA, Devaney KO, Giordano TJ, Weiss SW. Inflammatory myxohyaline tumor of distal exterimities with virocyte or Reed Sternberg-like cells: A distinctive lesion with features simulating inflammatory conditions, Hodgkin′s disease and various sarcomas. Mod Pathol 1998;11:384-91.
  • 5 Chahdi H, Damiri A, Oukabli M, Albouzidi A, Bouabid S, Lazrek K. Acral myxoinflammatory fibroblastic sarcoma. Orthop Traumatol Surg Res 2010;96:597-9.
  • 6 Sakaki M, Hirokawa M,Wakatsuki S, Sano T, Endo K,Fujii Y,et al.Acral myxoinflammatory fibroblastic sarcoma: A report of five cases and review of the literature.Virchows Arch 2003;442:25-30.
  • 7 Fletcher CD, Unni KK, Mertens F. WHO classification of tumours. Tumours of soft tissue and bone. Lyon, France: IARC; 2002.
  • 8 Naqvi A, Mukhopadhyay S, de la Roza G, Damron T. Little-finger mass in a 29-year-old man. Arch Pathol Lab Med 2005;129:1343-4.
  • 9 Yasuda T, Kanamori M, Nobukiyo M, Nogami S, Hori T, Kimura T. Acral myxoinflammatory fibroblastic sarcoma of the foot. J Exp Clin Cancer Res 2007;26:277-80.