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CC BY-NC-ND 4.0 · Avicenna J Med 2013; 03(04): 109-111
DOI: 10.4103/2231-0770.120504
CASE REPORT

Acral gangrene as a presentation of non-uremic calciphylaxis

Muhammad Hammadah
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Shruti Chaturvedi
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Jennifer Jue
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Andrew Blake Buletko
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Mohammed Qintar
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Mohammed Eid Madmani
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
,
Prashant Sharma
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, United States
› Author Affiliations
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Abstract

We are describing a case of 55-year-old obese female with significant history of uncontrolled rheumatoid arthritis, who recently had decreased her immune-suppression medications. She presented with extensive acral gangrene involving multiple fingers and toes. Clinical picture and laboratory findings were suggestive of vasculitis; however, skin biopsy established diagnosis of calciphylaxis, in settings of normal kidney function. Patient was treated with sodium thiosulfate with gradual improvement in her skin lesions.

Keywords

Acral gangrene - calciphylaxis - non uremic - sodium thiosulfate - vasculitis


Publication History

Article published online:
09 August 2021

© 2013. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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