CC BY-NC-ND 4.0 · Avicenna J Med 2015; 05(01): 16-20
DOI: 10.4103/2231-0770.148504

A longitudinal study to assess the impact of exercise on clinical, biochemical, and anthropometric parameters among the type 2 diabetes patients of South India

Pradeep Sukla
Department of Community Medicine, Shri Sathya Sai Medical College and Research Institute, Kancheepuram, Tamil Nadu, India
Saurabh RamBihariLal Shrivastava
Department of Community Medicine, Shri Sathya Sai Medical College and Research Institute, Kancheepuram, Tamil Nadu, India
Prateek Saurabh Shrivastava
Department of Community Medicine, Shri Sathya Sai Medical College and Research Institute, Kancheepuram, Tamil Nadu, India
› Author Affiliations


Aim: Aim of the study isto assess the scope of physical activity among type 2 diabetes mellitus (T2DM) patients residing in an urban area of SouthIndia. Materials and Methods: A longitudinal interventional study was conducted for a period of 8months (January 2014-August 2014) among patients of T2DM accessing the healthcare services at an Urban Health and Training Center (UHTC) of a Medical College located in Kancheepuram district, Tamil Nadu. Universal sampling method was employed and all diagnosed T2DM patients attending UHTC during the month of January were enrolled in the study provided they satisfied the inclusion and exclusion criteria. Overall 151 participants were considered for final analysis and all of them were subjected to indulge in moderate type of aerobic exercise in the form of brisk walking for 2.5 h spread over a period of 1 week, for the next 6months. Before and after the exercise regimen, cases were subjected to clinical evaluation, measurement of weight and waist circumference, and estimation of fasting and postprandial blood sugar; and the results were compared with the baseline estimates.The associations were tested using paired t-test for continuous (mean ΁ standard deviation ( SD)) variables. Results: Majority (86, 57%) of the diabetics were from the age group of 40-60 years with a definite female preponderance (82/151) in contrast to males (69/151). A significant reduction in both fasting and postprandial sugar was observed before and after the exercise. However, from the perspective of the weight and waist circumference, although a reduction was observed, the association was not statistically significant. Conclusion: The findings of the present longitudinal study suggest that compliance with moderate type of physical activity can significantly improve the fasting and postprandial blood sugar, apart from reduction in weight of T2DM patients.

Publication History

Article published online:
09 August 2021

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  • References

  • 1 World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Geneva: WHO press; 1999.
  • 2 Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, et al.; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Glucose). National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 2011;378:31-40.
  • 3 Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006;3:e442.
  • 4 Kinra S, Bowen LJ, Lyngdoh T, Prabhakaran D, Reddy KS, Ramakrishnan L, et al. Sociodemographic patterning of non-communicable disease risk factors in rural India: A cross sectional study. BMJ 2010;341:c4974.
  • 5 Chuang LM, Tsai ST, Huang BY, Tai TY. Diabcare-Asia 1998 Study Group. The status of diabetes control in Asia-a cross-sectional survey of 24 317 patients with diabetes mellitus in 1998. Diabet Med 2002;19:978-85.
  • 6 Narayanappa D, Rajani HS, Mahendrappa KB, Prabhakar AK. Prevalence of prediabetes in school-going children. Indian Pediatr 2011;48:295-9.
  • 7 World Health Organization. Global status report on non-communicable diseases-2010. Geneva: WHO press; 2011.
  • 8 Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.
  • 9 Park K. Epidemiology of chronic non-communicable diseases and conditions. In: Park K, editor. Text Book of Preventive and Social Medicine. 20 th ed. Jabalpur: Banarsidas Bhanot Publishers; 2009. p. 341-5.
  • 10 Majgi SM, Soudarssanane BM, Roy G, Das AK. Risk factors of diabetes mellitus in rural Puducherry. Online J Health Allied Scs 2012;11:4.
  • 11 World Health Organization. Preventing chronic diseases: A vital investment. Geneva: WHO press; 2005.
  • 12 Sato Y. Principle of physical exercise for diabetes: Exercise prescription. Nihon Rinsho 2002;60:256-60.
  • 13 Barengo NC, Tuomilehto J. Diabetes: Exercise benefits in type 2 diabetes mellitus. Nat Rev Endocrinol 2012;8:635-6.
  • 14 Dunstan D. Diabetes: Exercise and T2DM-move muscles more often! Nat Rev Endocrinol 2011;7:189-90.
  • 15 Jessen N, Goodyear LJ. Diabetes: Exercise and type 2 diabetes mellitus-good for body and mind? Nat Rev Endocrinol 2010;6:303-4.
  • 16 Nagi D, Gallen I. ABCD position statement on physical activity and exercise in diabetes. Pract Diabetes Int 2010;27:158-63.
  • 17 Colberg SR. Increasing insulin sensitivity. Diabetes Self Manag 2007;24:47-50.
  • 18 Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, et al.; American College of Sports Medicine, American Diabetes Association. Exercise and type 2 diabetes: The American College of Sports Medicine and the American Diabetes Association: Joint position statement executive summary. Diabetes Care 2010;33:2692-6.
  • 19 Colberg SR. Physical activity, insulin action, and diabetes prevention and control. Curr Diabetes Rev 2007;3:176-84.
  • 20 Morrison S, Colberg SR, Parson HK, Vinik AI. Exercise improves gait, reaction time and postural stability in older adults with type 2 diabetes and neuropathy. J Diabetes Complications 2014;28:715-22.
  • 21 Colberg SR, Grieco CR, Somma CT. Exercise effects on postprandial glycemia, mood, and sympathovagal balance in type 2 diabetes. J Am Med Dir Assoc 2014;15:261-6.
  • 22 World Health Organization: Global recommendations on physical activity for health; 2011. Available from: [Last accessed on 2014 Aug 22].
  • 23 Jeon CY, Lokken RP, Hu FB, van Dam RM. Physical activity of moderate intensity and risk of type 2 diabetes: A systematic review. Diabetes Care 2007;30:744-52.
  • 24 Lerman-Garber I, Aguilar-Salinas C, Tusie-Luna T, Velasquez D, Lobato-Valverde M, Osornio-Flores M, et al. Early-onset type 2 diabetes mellitus. The experience from a third level medical institution. Gac Med Mex 2010;146:179-84.
  • 25 Jali MV, Kambar S, Jali SM, Gowda S. Familial early onset of type-2 diabetes mellitus and its complications. N Am J Med Sci 2009;1:377-80.
  • 26 Colberg SR, Castorino K, Jovanovic L. Prescribing physical activity to prevent and manage gestational diabetes. World J Diabetes 2013;4:256-62.
  • 27 Colberg SR. Physical activity: The forgotten tool for type 2 diabetes management. Front Endocrinol (Lausanne) 2012;3:70.
  • 28 Boon H, Blaak EE, Saris WH, Keizer HA, Wagenmakers AJ, van Loon LJ. Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery. Diabetologia 2007;50:103-12.
  • 29 Aguiar EJ, Morgan PJ, Collins CE, Plotnikoff RC, Callister R. Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: A systematic review with meta-analysis. Int J Behav Nutr Phys Act 2014;11:2.
  • 30 Tudor-Locke C, Schuna JM Jr. Steps to preventing type 2 diabetes: Exercise, walk more, or sit less? Front Endocrinol (Lausanne) 2012;3:142.
  • 31 Reiner M, Niermann C, Jekauc D, Woll A. Long-term health benefits of physical activity - A systematic review of longitudinal studies. BMC Public Health 2013;13:813.
  • 32 Frost J, Garside R, Cooper C, Britten N. A qualitative synthesis of diabetes self-management strategies for long term medical outcomes and quality of life in the UK. BMC Health Serv Res 2014;14:348.