CC BY-NC-ND 4.0 · Avicenna J Med 2015; 05(01): 21-23
DOI: 10.4103/2231-0770.148507
BRIEF REPORT

Ventricular septal defect and bivalvular endocarditis

Kate E Birkenkamp
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
,
Jay J Jin
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
,
Raina Shivashankar
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
,
Hayan Jouni
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
,
Larry M Baddour
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
,
Lori A Blauwet
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
› Author Affiliations

Abstract

A 63-year-old man presented with generalized fatigue, chills, malaise, dyspnea, intermittent fevers, and 50-pound weight loss of 4 months′ duration. Blood cultures were positive for pan-sensitive Streptococcus anginosus. Transesophageal echocardiography showed an 11 mm × 3 mm mobile mass attached to the mitral valve, a 16 mm × 16 mm mobile mass attached to the pulmonary valve, and a small membranous ventricular septal defect. The patient received 12 weeks of intravenous (IV) antibiotics with eventual resolution of the masses. Multi-valve endocarditis involving both the left and right chambers is rarely reported without prior history of IV drug use or infective endocarditis. Our case emphasizes the importance of careful assessment for ventricular septal defects or extra-cardiac shunts in individuals who present with simultaneous right and left-sided endocarditis.



Publication History

Article published online:
09 August 2021

© 2015. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 Guntheroth WG, Spiers PS. Is operative closure of a small ventricular septal defect required after an episode of infective endocarditis? Am J Cardiol 2005;95:960-2.
  • 2 López J, Revilla A, Vilacosta I, Sevilla T, García H, Gómez I, et al. Multiple-valve infective endocarditis: Clinical, microbiologic, echocardiographic, and prognostic profile. Medicine (Baltimore) 2011;90:231-6.
  • 3 Nakamura K, Satomi G, Sakai T, Ando M, Hashimoto A, Koyanagi H, et al. Clinical and echocardiographic features of pulmonary valve endocarditis. Circulation 1983;67:198-204.
  • 4 Itoh N, Shigematsu H, Itoh M, Yamada H. Right-sided infective endocarditis combined with mitral involvement in a patient with ventricular septal defect. Acta Pathol Jpn 1985;35:459-71.
  • 5 Kang DH, Kim YJ, Kim SH, Sun BJ, Kim DH, Yun SC, et al. Early surgery versus conventional treatment for infective endocarditis. N Engl J Med 2012;366:2466-73.