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CC BY-NC-ND 4.0 · Avicenna J Med 2016; 06(04): 109-112
DOI: 10.4103/2231-0770.191447
ORIGINAL ARTICLE

Etiological causes of pancytopenia: A report of 137 cases

Osman Yokus
Department of Hematology, Ministry of Health, Istanbul Training and Research Hospital, Istanbul, Turkey
,
Habip Gedik
Department of Infectious Diseases and Clinical Microbiology, Ministry of Health, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
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Abstract

Objective: The aim of this study is to evaluate the etiological causes of pancytopenia in patients who were admitted to the hematology ward due to pancytopenia. Materials and Methods: All patients who were admitted to the hematology ward of Ministry of Health Istanbul Training and Research Hospital due to pancytopenia between 2013 and 2015 were retrospectively evaluated regarding etiological causes. Results: A total of 137 patients was evaluated. The etiological causes of pancytopenia were recorded as Vitamin B12 deficiency (n: 24; 17%), chronic liver disease (n: 21; 15%), malignancy (n: 19; 13%), myelodysplastic syndrome (n: 18; 13%), aplastic anemia (n: 11; 8%), rheumatic diseases (n: 7; 5%), and endocrine causes (n: 3; 2%). Conclusion: The etiological causes of pancytopenia vary depends on patients′ age, gender, country, and other conditions. Vitamin B12 deficiency is the most common treatable cause of pancytopenia. Most of the etiological causes could be diagnosed with laboratory analysis and radiological imagings, without the need of a bone marrow examination.

Keywords

Chronic liver disease - myelodysplastic syndrome - pancytopenia - Vitamin B12 deficiency


Publication History

Article published online:
09 August 2021

© 2016. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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