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CC BY-NC-ND 4.0 · South Asian J Cancer 2016; 05(04): 189-191
DOI: 10.4103/2278-330X.195341
CANCER EPIDEMIOLOGY: Original Article

Modified metabolic syndrome and second cancers in women: A case control study

Carlos-Manuel Ortiz-Mendoza
Department of Surgery, School of Medicine, National Autonomous University of Mexico, Mexico City
,
Ernesto Pérez-Chávez
Department of General Surgery, Hospital General Tacuba, ISSSTE, Mexico City
,
Tania-Angélica De-la Fuente-Vera
Department of General Surgery, Hospital General Tacuba, ISSSTE, Mexico City
› Author Affiliations
Source of Support: Nil.
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Abstract

Background: According to some studies, the metabolic syndrome causes diverse primary cancers; however, there is no evidence about metabolic syndrome impact on second cancers development in women. Aim: To find out the implication of the modified metabolic syndrome in women with second cancers. Materials and Methods: This was a case-control study, at a general hospital in Mexico City, in women with second cancers (cases) and age-matched women with only one neoplasm (controls). The analysis comprised: Tumor (s), anthropometric features, and body mass index (BMI); moreover, presence of diabetes mellitus, hypertension, and fasting serum levels of total cholesterol, triglycerides and glucose. Results: The sample was of nine cases and 27 controls. In cases, the metabolic syndrome (diabetes mellitus or glucose > 99 mg/dL + hypertension or blood pressure ≥ 135/85 mm Hg + triglycerides > 149 mg/dL or BMI ≥ 30 kg/m 2 ) was more frequent (odds ratio 20.8, 95% confidence interval: 1.9-227.1). Conclusion: Our results suggest that in women, the modified metabolic syndrome may be a risk factor for second cancers.

Key words

Adult; cancer - female - metabolic syndrome - Mexico - neoplasms - neoplasms - second primary/etiology - obesity


Publication History

Article published online:
28 December 2020

© 2016. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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