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CC BY-NC-ND 4.0 · South Asian J Cancer 2013; 02(04): 250-253
DOI: 10.4103/2278-330x.119886
THROUGH THE MICROSCOPE: Original Article

Pattern of salivary gland tumors in Manipur, India: A 10 year study

Rajesh Singh Laishram
Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India
,
Arun Kumar K.
Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India
,
Gayatri Devi Pukhrambam
Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India
,
Sharmila Laishram
Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India
,
Kaushik Debnath
Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India
› Author Affiliations Source of Support: Nill.
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Abstract

Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011) retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08). Parotid (56.65%) was the commonest gland involved followed by submandibular gland (31.73%). Neoplastic lesions comprised of 78 (75%) cases and non-neoplastic lesions constituted 25% (26 cases). Among the neoplastic lesions, benign lesions (53.85%) predominated over malignant lesions (21.15%). Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

Key words

Mucoepidermoid carcinoma - pleomorphic adenoma - salivary gland


Publication History

Article published online:
31 December 2020

© 2013. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Ezeanolue BC. Salivary gland neoplasms: A descriptive analysis of the pattern seen in Enugu. West Afr J Med 1999;18:179-82.
  • 2 Odukoya O. Pleomorphic adenoma of salivary glands in Lagos, Nigeria. Afr J Med Sci 1990;19:195-9.
  • 3 Vuhahula EA. Salivary gland tumors in Uganda: Clinical pathological study. Afr Health Sci 2004;4:15-23.
  • 4 Nepal A, Chettri ST, Joshi RR, Bhattarai M, Ghimire A, Karki S. Primary salivary gland tumors in eastern Nepal tertiary care hospital. J Nepal Health Res Counc 2010;8:31-4.
  • 5 National cancer Registry programme. Annual report of Population based cancer registry, Imphal, ManipurState. Indian Counc Med Res 2009:33-4.
  • 6 Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 1985;146:51-8.
  • 7 Arotiba GT. Salivary gland neoplasms in Lagos, Nigeria. West Afr J Med 1996;15:11-7.
  • 8 Ma′aita JK, Al-Kaisi N, Al-Tamimi S, Wraikat A. Salivary gland tumors in Jordan: A retrospective study of 221 patients. Croat Med J 1999;40:539-42.
  • 9 Vargas PA, Gerhard R, AraújoFilho VJ, de Castro IV. Salivary gland tumors in a Brazilian population: A retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo 2002;57:271-6.
  • 10 Satko I, Stanko P, Longauerová I. Salivary gland tumours treated in the stomatological clinics in Bratislava. J Craniomaxillofac Surg 2000;28:56-61.
  • 11 Ahmad S, Lateef M, Ahmad R. Clinicopathological study of primary salivary gland tumours in Kashmir. JK Pract 2002;9:231-3.
  • 12 Ochicha O, Malami S, Mohammed A, Atanda A. A histopathologic study of salivary gland tumors in Kano, northern Nigeria. Indian J Pathol Microbiol 2009;52:473-6.
  • 13 Loyola AM, de Araújo VC, de Sousa SO, de Araújo NS. Minor salivary gland tumours. A retrospective study of 164 cases in a Brazilian population. Eur J Cancer B Oral Oncol 1995;31B:197-201.
  • 14 Rivera-Bastidas H, Ocanto RA, Acevedo AM. Intraoral minor salivary gland tumors: A retrospective study of 62 cases in a Venezuelan population. J Oral Pathol Med 1996;25:1-4.
  • 15 Ito FA, Ito K, Vargas PA, de Almeida OP, Lopes MA. Salivary gland tumors in a Brazilian population: A retrospective study of 496 cases. Int J Oral Maxillofac Surg 2005;34:533-6.
  • 16 Frade Gonzalez C, Lozano Ramirez A, Garcia Caballero T, Labella Caballero T. Epidemiological study of salivary gland tumours. Rev Laryngol Otol Rhinol (Bord) 1999;120:331-6.
  • 17 Li LJ, Li Y, Wen YM, Liu H, Zhao HW. Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol 2008;44:187-92.
  • 18 Toida M, Shimokawa K, Makita H, Kato K, Kobayashi A, Kusunoki Y, et al. Intraoral minor salivary gland tumors: A clinicopathological study of 82 cases. Int J Oral Maxillofac Surg 2005;34:528-32.
  • 19 Lopes MA, Kowalski LP, da Cunha Santos G, Paes de Almeida O. A clinicopathologic study of 196 intraoral minor salivary gland tumours. J Oral Pathol Med 1999;28:264-7.
  • 20 Chung YF, Khoo ML, Heng MK, Hong GS, Soo KC. Epidemiology of Warthin′s tumour of the parotid gland in an Asian population. Br J Surg 1999;86:661-4.
  • 21 Eveson JW, Cawson RA. Warthin′s tumor (cystadenolymphoma) of salivary glands. A clinicopathologic investigation of 278 cases. Oral Surg Oral Med Oral Pathol 1986;61:256-62.
  • 22 Pinkston JA, Cole P. Incidence rates of salivary gland tumors: Results from a population-based study. Otolaryngol Head Neck Surg 1999;120:834-40.
  • 23 Batsakis JG, Regezi JA. The pathology of head and neck tumors: Salivary glands, part 1. Head Neck Surg 1978;1:59-68.