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CC BY-NC-ND 4.0 · J Lab Physicians 2018; 10(04): 406-409
DOI: 10.4103/JLP.JLP_85_18
Original Article

Clinico-microbiological profile of healthcare associated pneumonia in critically ill patients at level-I trauma centre of India

Minu Kumari
Division of Trauma Surgery and Critical Care, JPNATC, AIIMS, New Delhi, India
,
Neha Rastogi
Department of Laboratory Medicine, JPNATC, AIIMS, New Delhi, India
,
Rajesh Malhotra
Department of Orthopaedics, AIIMS, New Delhi, India
,
Purva Mathur
Division of Trauma Surgery and Critical Care, JPNATC, AIIMS, New Delhi, India
› Author Affiliations Financial support and sponsorship Nil.
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ABSTRACT

INTRODUCTION: Device-associated infections constitute the majority of health-care infections in Intensive Care Units (ICUs). Trauma patients are more prone to acquire such infections; ventilator-associated pneumonia (VAP) being the most common Health care associated infections (HAI) in ICU has serious implications such as increased morbidity, prolonged hospital stay, and mortality. This study aims to compare the clinicomicrobiological profile of VAP and non-VAP trauma patients at Level I trauma center.

MATERIALS AND METHODS: A 4-year retrospective study of prospectively maintained database was conducted at Level 1 trauma center from January 2013 to December 2016. The patients were classified into two groups named VAP and non-VAP patients. VAP patients were defined according to the criteria of the Centers for Disease Control and Prevention. The data were compiled and analyzed. Statistical data were analyzed using SPSS version 21 software.

RESULTS: During the study period, 134 (13%) cases of VAP and 909 (87%) non-VAP cases were observed in our study. The total number of ventilator days for VAP patients was 5128 days, which ranged from 2 to 82 days (median 42 days). The length of hospital stay in non-VAP category ranged from 1 to 390 days (median 195.5 days). Inhospital mortality was observed in 62 (46%) patients with VAP. Three hundred and eighteen (35%) non-VAP patients had also had a fatal outcome. Gram-negative organisms, most commonly Acinetobacter spp. (13, 21%), were reported in the fatal VAP patients.

CONCLUSION AND DISCUSSION: Higher rate of mortality was observed in patients with VAP in comparison to non-VAP patients, both being on mechanical ventilation. Early recognition of VAP, implementation of proper VAP preventive bundle strategies, and stringent infection control practices are essential mandates to prevent VAP.

Keywords

Antimicrobial - infection - mortality - resistance


Publication History

Received: 25 June 2018

Accepted: 31 August 2018

Article published online:
20 February 2020

© 2018.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

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