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CC BY-NC-ND 4.0 · J Lab Physicians 2018; 10(01): 034-037
DOI: 10.4103/JLP.JLP_90_17
Original Article

Thrombocytosis in children: Clinico-hematological profile from a single centre in Eastern India

Rachita Sarangi
Department of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, India
,
Sarita Pradhan
Department of Pathology, IMS and Sum Hospital, Bhubaneswar, Odisha, India
,
Avantika Dhanawat
Department of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, India
,
Rashmi Patanayak
Department of Pathology, IMS and Sum Hospital, Bhubaneswar, Odisha, India
,
Gautam Benia
Department of Paediatrics, IMS and Sum Hospital, Bhubaneswar, Odisha, India
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Financial support and sponsorship: Nil
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Abstract

BACKGROUND AND OBJECTIVE: Thrombocytosis is not an uncommon finding in hemograms of children with an incidence of 6%–15% among hospitalized children. This study aims to determine the etiology of thrombocytosis and analyze various platelet parameters in children attending our hospital.

MATERIALS AND METHODS: A prospective observational study was carried out in a tertiary care center in Odisha, in eastern part of India, for 6 months from July 2016 to December 2016. All children of age group 1–14 years of age attending pediatrics and other pediatric super specialty outdoors and/or admitted to indoors and whose complete blood counts (CBC) were done were included in the study. The CBC parameters such as hemoglobin, red blood cell indices, and platelet indices (platelet distribution width [PDW], mean platelet volume [MPV], platelet large cell ratio [P-LCR]) were noted.

RESULTS: Out of 2500 hemograms done in pediatrics age group, 272 (10.8%) patients showed thrombocytosis. About 99.6% of cases were of secondary thrombocytosis. Only one case of primary thrombocytosis was encountered. The most common cause of secondary thrombocytosis was infection (39.5%) alone followed by iron deficiency anemia (14.1%). With increasing platelet counts, a decrease in MPV, P-LCR, and PDW was noted which was statistically significant (P < 0.05).

CONCLUSION: Thrombocytosis is not rare (10.8%) in children. Secondary thrombocytosis is common and predominatly attributed to infection.

Keywords

Platelet indices - primary - secondary - thrombocytosis


Publikationsverlauf

Eingereicht: 13. Mai 2017

Angenommen: 04. Juli 2017

Artikel online veröffentlicht:
19. Februar 2020

© 2018.

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

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