CC BY-NC-ND 4.0 · Avicenna J Med 2021; 11(01): 15-19
DOI: 10.4103/ajm.ajm_73_20
Original Article

Evaluation of antibiotic prescribing pattern in pediatrics in a tertiary care hospital

Rinta Mathew
Department of Clinical Pharmacy, Bharati Hospital and Research Centre, Poona College of Pharmacy, Pune, Maharashtra, India
,
Humera Sayyed
Department of Clinical Pharmacy, Bharati Hospital and Research Centre, Poona College of Pharmacy, Pune, Maharashtra, India
,
Subhashree Behera
Department of Clinical Pharmacy, Bharati Hospital and Research Centre, Poona College of Pharmacy, Pune, Maharashtra, India
,
Keemya Maleki
Department of Clinical Pharmacy, Bharati Hospital and Research Centre, Poona College of Pharmacy, Pune, Maharashtra, India
,
Sunita Pawar
Department of Clinical Pharmacy, Bharati Hospital and Research Centre, Poona College of Pharmacy, Pune, Maharashtra, India
› Author Affiliations

Subject Editor: Financial support and sponsorship Nil.

Abstract

Background: The irrational use of antibiotics is a global issue and it can lead to morbidity, mortality, and increased health care costs. Hence, proper use of antibiotics is imperative and should be included in the pharmaceutical care plan. Objective: The objective of this study was to evaluate the prescribing pattern of antibiotics for children using WHO core prescribing indicators. Materials and Methods: A prospective, observational study was carried for 6 months in the pediatric department at a tertiary care hospital, Pune. The WHO prescribing indicators were used to evaluate the prescriptions, and the ideal WHO range was considered as a determining factor for rational prescription. Results: A total of 302 patients were included in the study, with a mean patient age of 4.92 ± 4 years. The average number of drugs per encounter was 6.12 (WHO standard is less than 2). The percentage of antibiotics prescribed was 26.3% with an average of 1.63 antibiotics per prescription. Of the 493 antibiotics, 85.59% were injectable which is higher than the WHO standard of 13.4–24.1%. A near-optimal value of 99.59% antibiotics was prescribed from the hospital formulary which is similar to WHO standards, and the antibiotics prescribed with generic names were 25.76%. The most common class of antibiotics prescribed were cephalosporins and penicillins. Conclusion: Polypharmacy, high injectable use, and non-adherence to generic prescription were common in our tertiary care center. Continuous audits, training, and new treatment protocols are recommended.



Publication History

Article published online:
06 August 2021

© 2021. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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