Eosinophilic granuloma is a localized form of Langerhans cell histiocytosis, most
commonly involving the skeletal system. Their origin from the dura is rare with only
a handful of cases on record. We present one such rare case of an eosinophilic granuloma
originating from the dura mater with secondary osseous invasion in an 11-year-old
female child who presented with a swelling in the right parietal region. Magnetic
resonance imaging demonstrated an enhancing mass with a wide dural attachment with
a lytic lesion in the overlying skull. Right parietal extended craniotomy was done
with the excision of mass from the dura. Histopathological features of mass were characteristic
of eosinophilic granuloma which was confirmed by positive immunohistochemical staining
for CD1a.
Key-words:
Dura - eosinophilic granuloma - immunohistochemical - Langerhans cell histiocytosis
