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CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(01): 201-205
DOI: 10.4103/ajns.AJNS_49_18
Original Article

Prevalence of postconcussion syndrome after mild traumatic brain injury in young adults from a single neurosurgical center in east coast of Malaysia

Buveinthiran Balakrishnan
1   Department of Surgery, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan Campus, Pahang
,
Razman Rus
2   Department of Community Medicine, International Islamic University Malaysia, Kuantan Campus, Pahang
,
Kin Chan
3   Department of Neurosurgery, International Islamic University Malaysia, Kuantan Campus, Pahang
,
Arvind Martin
4   Department of Neurosurgery, Hospital Tengku Ampuan Afzan, Kuantan, Pahang
,
Mohamed Awang
1   Department of Surgery, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan Campus, Pahang
3   Department of Neurosurgery, International Islamic University Malaysia, Kuantan Campus, Pahang
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Context: Postconcussion syndrome (PCS) is a set of symptoms occurred after a mild traumatic brain injury (MTBI). Aims: This study aims to determine the prevalence of PCS in a young adult population from a single Neurological Centre in Malaysia's East Coast and to evaluate the factors associated with PCS in MTBI patients. Settings and Design: This was a cross-sectional study conducted in a Neurological Centre at Hospital Tengku Ampuan Afzan, Kuantan, Pahang, Malaysia, from January 2016 to December 2016. Subjects and Methods: A total of 209 patients; 133 males and 76 females, in the age range of 16–84 years, were randomly recruited for this study. All the selected patients were subjected to the checklist for diagnosis of PCS as per International Statistical Classification of Diseases and Related Health Problems 10th edition classification at a 2-week interval. Statistical Analysis Used: Descriptive statistic and Multivariable Logistic Regression Model were used for frequency and percentage analyses of categorical variables, using SPSS version 23.0. Results: Only 20 patients were identified with PCS. There were more female (70%) patients with PCS than the male (30%) patients. The prevalence of PCS for 2 weeks, 3 and 6 months since injuries were 9.6%, 8.1%, and 8.1% respectively. Majority (80%) of the patients were found to have PCS due to road traffic accidents, while the remaining were attributed to assault (15%), and falls (5%). Among the sample population, 25% were smokers, while 10% of them had either skull fracture or premorbidity. Conclusion: Less than 10% of patients with MTBI had PCS after 6 months' following trauma. None of the variables tested were significant factors for the development of PCS symptoms.

Key-words:

Clinical symptoms - mechanism of injury - mild traumatic brain injury - postconcussion syndrome - trauma patient

Financial support and sponsorship

This study was financially supported by the Research Initiative Grant Scheme (RIGS) 2015.




Publikationsverlauf

Artikel online veröffentlicht:
09. September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Kay T, Harrington DE, Adams R, Andersen T, Berrol S, Cicerone K, et al. Definition of mild traumatic brain injury. J Head Trauma Rehabil 1993;8:86-7.
  • 2 Katz DI, Cohen SI, Alexander MP. Mild traumatic brain injury. Handb Clin Neurol 2015;127:131-56.
  • 3 Kraus J, Schaffer K, Ayers K, Stenehjem J, Shen H, Afifi AA. Physical complaints, medical service use, and social and employment changes following mild traumatic brain injury: A 6-month longitudinal study. J Head Trauma Rehabil 2005;20:239-56.
  • 4 Cassidy JD, Carroll LJ, Peloso PM, Borg J, von Holst H, Holm L, et al. Incidence, risk factors and prevention of mild traumatic brain injury: Results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med 2004;43 suppl:28-60.
  • 5 Ganti L, Khalid H, Patel PS, Daneshvar Y, Bodhit AN, Peters KR, et al. Who gets post-concussion syndrome? An emergency department-based prospective analysis. Int J Emerg Med 2014;7:31.
  • 6 Dean PJ, O'Neill D, Sterr A. Post-concussion syndrome: Prevalence after mild traumatic brain injury in comparison with a sample without head injury. Brain Inj 2012;26:14-26.
  • 7 Bohnen N, Twijnstra A, Jolles J. Persistence of postconcussional symptoms in uncomplicated, mildly head-injured patients: A prospective cohort study. Neuropsychiatry Neuropsychol Behav Neurol 1993;6:193-200.
  • 8 Mittenberg W, Strauman S. Diagnosis of mild head injury and the postconcussion syndrome. J Head Trauma Rehabil 2000;15:783-91.
  • 9 Jotwani V, Harmon KG. Postconcussion syndrome in athletes. Curr Sports Med Rep 2010;9:21-6.
  • 10 Binder LM. Persisting symptoms after mild head injury: A review of the postconcussive syndrome. J Clin Exp Neuropsychol 1986;8:323-46.
  • 11 Rutherford WH. Post Concussion Symptoms: Relationship to Acute Neurological Indices, Individual Differences, and Circumstances of Injury. Mild Head Injury. New York: Oxford University Press; 1989. p. 217-28.
  • 12 Binder LM, Rohling ML, Larrabee GJ. A review of mild head trauma. Part I: Meta-analytic review of neuropsychological studies. J Clin Exp Neuropsychol 1997;19:421-31.
  • 13 Spinos P, Sakellaropoulos G, Georgiopoulos M, Stavridi K, Apostolopoulou K, Ellul J, et al. Postconcussion syndrome after mild traumatic brain injury in Western Greece. J Trauma 2010;69:789-94.
  • 14 Belanger HG, Vanderploeg RD, Curtiss G, Warden DL. Recent neuroimaging techniques in mild traumatic brain injury. J Neuropsychiatry Clin Neurosci 2007;19:5-20.
  • 15 Ponsford J, Willmott C, Rothwell A, Cameron P, Kelly AM, Nelms R, et al. Factors influencing outcome following mild traumatic brain injury in adults. J Int Neuropsychol Soc 2000;6:568-79.
  • 16 Carroll LJ, Cassidy JD, Peloso PM, Borg J, von Holst H, Holm L, et al. Prognosis for mild traumatic brain injury: Results of the WHO Collaborating Centre Task Force on mild traumatic brain injury. J Rehabil Med 2004;43 suppl:84-105.
  • 17 Stiell IG, Wells GA, Vandemheen K, Clement C, Lesiuk H, Laupacis A, et al. The Canadian CT head rule for patients with minor head injury. Lancet 2001;357:1391-6.
  • 18 Thornhill S, Teasdale GM, Murray GD, McEwen J, Roy CW, Penny KI, et al. Disability in young people and adults one year after head injury: Prospective cohort study. BMJ 2000;320:1631-5.
  • 19 Dischinger PC, Ryb GE, Kufera JA, Auman KM. Early predictors of postconcussive syndrome in a population of trauma patients with mild traumatic brain injury. J Trauma 2009;66:289-96.
  • 20 Stulemeijer M, Vos PE, Bleijenberg G, van der Werf SP. Cognitive complaints after mild traumatic brain injury: Things are not always what they seem. J Psychosom Res 2007;63:637-45.
  • 21 Kashluba S, Paniak C, Casey JE. Persistent symptoms associated with factors identified by the WHO Task Force on Mild Traumatic Brain Injury. Clin Neuropsychol 2008;22:195-208.
  • 22 Meares S, Shores EA, Taylor AJ, Batchelor J, Bryant RA, Baguley IJ, et al. Mild traumatic brain injury does not predict acute postconcussion syndrome. J Neurol Neurosurg Psychiatry 2008;79:300-6.
  • 23 McLean SA, Kirsch NL, Tan-Schriner CU, Sen A, Frederiksen S, Harris RE, et al. Health status, not head injury, predicts concussion symptoms after minor injury. Am J Emerg Med 2009;27:182-90.
  • 24 McCauley SR, Boake C, Levin HS, Contant CF, Song JX. Postconcussional disorder following mild to moderate traumatic brain injury: Anxiety, depression, and social support as risk factors and comorbidities. J Clin Exp Neuropsychol 2001;23:792-808.
  • 25 Preiss-Farzanegan SJ, Chapman B, Wong TM, Wu J, Bazarian JJ. The relationship between gender and postconcussion symptoms after sport-related mild traumatic brain injury. PM R 2009;1:245-53.
  • 26 Savola O, Hillbom M. Early predictors of post-concussion symptoms in patients with mild head injury. Eur J Neurol 2003;10:175-81.
  • 27 Stulemeijer M, van der Werf S, Borm GF, Vos PE. Early prediction of favourable recovery 6 months after mild traumatic brain injury. J Neurol Neurosurg Psychiatry 2008;79:936-42.
  • 28 Hou R, Moss-Morris R, Peveler R, Mogg K, Bradley BP, Belli A. When a minor head injury results in enduring symptoms: A prospective investigation of risk factors for postconcussional syndrome after mild traumatic brain injury. J Neurol Neurosurg Psychiatry 2012;83:217-23.
  • 29 Begaz T, Kyriacou DN, Segal J, Bazarian JJ. Serum biochemical markers for post-concussion syndrome in patients with mild traumatic brain injury. J Neurotrauma 2006;23:1201-10.