Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(02): 264-265
DOI: 10.4103/ijmpo.ijmpo_114_18
Practitioner Section

Primary Neuroendocrine Carcinoma of Kidney: Report of a Rare Case

Sandeep Bhaskar
Department of Radiotherapy, SMS Medical College and Attached Group of Hospitals, Jaipur, Rajasthan, India
,
Kartick Rastogi
Department of Radiotherapy, SMS Medical College and Attached Group of Hospitals, Jaipur, Rajasthan, India
,
Shivani Gupta
Department of Radiotherapy, SMS Medical College and Attached Group of Hospitals, Jaipur, Rajasthan, India
,
Arpita Jindal
Department of Pathology, SMS Medical College and Attached Group of Hospitals, Jaipur, Rajasthan, India
› Author Affiliations Financial support and sponsorship Nil.
› Further Information
   Permissions and Reprints

Abstract

Primary neuroendocrine tumor (NET) of kidney is extremely rare, with <100 cases reported so far. The aim of the present case study is to discuss the clinical and pathological findings of renal NET and review of the available literature. We herein report the case of a 42-year-old female patient, who presented with pain abdomen and hematuria. Immunohistochemistry of her nephrectomy specimen was positive for chromogranin A and CD56 and negative for uroplakin II, P40, and CD10. KI index was 60%. Due to rarity of the tumor, there are no established guidelines available for its treatment. She was treated with combination chemotherapy of cisplatin and etoposide.

Keywords

Neuroendocrine tumor - rare - renal


Publication History

Received: 14 May 2018

Accepted: 21 June 2018

Article published online:
23 May 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Litwinowicz R, Szpor J, Januś G, Worek M, Okoń K. Primary carcinoid tumour in horseshoe kidney. Pol J Pathol 2011; 62: 72-4
    PubMedGoogle Scholar
  • 2 Murali R, Kneale K, Lalak N, Delprado W. Carcinoid tumors of the urinary tract and prostate. Arch Pathol Lab Med 2006; 130: 1693-706
    CrossrefPubMedGoogle Scholar
  • 3 Kawajiri H, Onoda N, Ohira M, Nakatani T, Wakasa K, Ishikawa T. et al. Carcinoid tumor of the kidney presenting as a large abdominal mass: Report of a case. Surg Today 2004; 34: 86-9
    CrossrefPubMedGoogle Scholar
  • 4 Fjällskog ML, Granberg DP, Welin SL, Eriksson C, Oberg KE, Janson ET. et al. Treatment with cisplatin and etoposide in patients with neuroendocrine tumors. Cancer 2001; 92: 1101-7
    CrossrefPubMedGoogle Scholar
  • 5 Romero FR, Rais-Bahrami S, Permpongkosol S, Fine SW, Kohanim S, Jarrett TW. et al. Primary carcinoid tumors of the kidney. J Urol 2006; 176: 2359-66
    CrossrefPubMedGoogle Scholar
  • 6 Hansel DE, Epstein JI, Berbescu E, Fine SW, Young RH, Cheville JC. Renal carcinoid tumor: A clinicopathologic study of 21 cases. Am J Surg Pathol 2007; 31: 1539-44
    CrossrefPubMedGoogle Scholar
  • 7 Lane BR, Jour G, Zhou M. Renal neuroendocrine tumors. Indian J Urol 2009; 25: 155-60
    CrossrefPubMedGoogle Scholar
  • 8 Lane BR, Chery F, Jour G, Sercia L, Magi-Galluzzi C, Novick AC. et al. Renal neuroendocrine tumours: A clinicopathological study. BJU Int 2007; 100: 1030-5
    PubMedGoogle Scholar
  • 9 Korkmaz T, Seber S, Yavuzer D, Gumus M, Turhal NS. Primary renal carcinoid: Treatment and prognosis. Crit Rev Oncol Hematol 2013; 87: 256-64
    CrossrefPubMedGoogle Scholar