Bulky Pelvic Hodgkin Lymphoma in a Prepubertal Girl

Sidharth Totadri; Deepak Bansal; Amanjit Bal; Prema Menon

doi:10.4103/ijmpo.ijmpo_150_16

Indian Journal of Medical and Paediatric Oncology, Table of Contents

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(02): 226-227
DOI: 10.4103/ijmpo.ijmpo_150_16

Case Report

Bulky Pelvic Hodgkin Lymphoma in a Prepubertal Girl

Authors

Sidharth Totadri

Department of Pediatrics, Advanced Pediatrics Center, Pediatric Hematology-Oncology Unit, Chandigarh, India
Deepak Bansal

Department of Pediatrics, Advanced Pediatrics Center, Pediatric Hematology-Oncology Unit, Chandigarh, India
Amanjit Bal

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Prema Menon

Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Abstract

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Abstract

Pure infra-diaphragmatic presentation is rare in pediatric Hodgkin lymphoma (HL). Isolated pelvic presentation is restricted to case reports in adults. We describe a unique presentation of HL as a primary pelvic disease in an 11-year-old prepubertal girl. She was treated based on the Euronet-Paediatric Hodgkin's Lymphoma Group protocol (EuroNet-PHL-C1) recommendations and assigned to treatment Group 2 (Stage IIB). The patient had bulky disease and a suboptimal response on interim 18-fluorodeoxyglucose positron emission tomography. The child was administered chemotherapy alone. Pelvic radiotherapy was consciously avoided due to the high risk of gonadal failure. She remains disease-free for 18 months now. Treatment of pediatric HL necessitates a delicate balance between achieving cure as well as avoiding serious late effects of therapy.

Keywords

Hypogonadism - infradiaphragmatic - late effects - positron emission tomography scan - radiation

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References

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