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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(02): 158-164
DOI: 10.4103/ijmpo.ijmpo_40_16
Original Article

A Significant Breakthrough in the Incidence of Childhood Cancers and Evaluation of its Risk Factors in Southern Iran

Asma Erjaee
Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
,
Maryam Niknam
Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran
,
Ahmadreza Sadeghi
Esthetic and Restorative Dentist, Shiraz University of Medical Sciences, Shiraz, Iran
,
Maryam Dehghani
Department of Pharmacology and Toxicology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
,
Zeinab Safaei
Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran
,
Saeed Hosseini Teshnizi
Clinical Research Development Center of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
,
Mehran Karimi
Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Background and Objective: This study investigates epidemiologic and practical information about the incidence and risk factors of childhood cancer in a population of Southern Iranian children. Materials and Methods: A total number of 300 cancer patients along with 600 age- and gender-matched healthy control were interviewed by a trained physician regarding their demographic characteristics, and major family-associated risk factors, childhood malignancies. Results: The average annual percentage change for cancers in the studied population is calculated as 45%. Our study indicated that possible risk factors which could contribute to the development of childhood cancer are maternal oral contraceptive pill use during pregnancy, exposure to radiation during pregnancy, parental smoking, residence near high voltage electricity lines, exposure to pesticides and fertilizers, patient allergy, contact with domestic animals and father's educational degree. Furthermore, new ecological risk factors such as air pollution due to nonstandard petroleum or toxic inhalant particles, nonhealthy food consumption, and satellite jamming are other predisposing factors. Conclusion: Our study reported a higher average annual percentage change of childhood cancers in our area, compared to the existing literature. In conclusion, detection and prevention of the consistent and possible new environmental risk factors such as nonstandard petroleum or satellite jamming from all around the country should be taking into consideration.

Keywords

Cancers - children - incidence - risk factors


Publication History

Article published online:
06 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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