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DOI: 10.4103/ijmpo.ijmpo_55_16
Longitudinally Extensive Transverse Myelitis as Presenting Manifestation of Lung Adenocarcinoma
Autoren
Financial support and sponsorship Nil.
Abstract
Longitudinally extensive transverse myelitis (LETM) is an unusual manifestation of systemic malignancy. It has been mainly reported with lung cancers and lymphoproliferative malignancy. LETM in systemic malignancy can be caused by either intramedullary metastases or paraneoplastic syndrome. Occurrence of LETM as the first manifestation of malignancy has been rarely reported. We present clinical, laboratory, and imaging findings of a 66-year-old man with nonsmall-cell lung (adeno) carcinoma, who presented with LETM without having any cardinal manifestations of lung malignancy. The rarity of the disease and especially such a presentation can cause considerable delay in the diagnosis and treatment.
Publikationsverlauf
Artikel online veröffentlicht:
23. Juni 2021
© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
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References
- 1 Kitley JL, Leite MI, George JS, Palace JA. The differential diagnosis of longitudinally extensive transverse myelitis. Mult Scler 2012; 18: 271-85
- 2 Ojeda VJ. Necrotizing myelopathy associated with malignancy. A clinicopathologic study of two cases and literature review. Cancer 1984; 53: 1115-23
- 3 Jain RS, Gupta PK, Agrawal R, Tejwani S, Kumar S. Longitudinally extensive transverse myelitis as presenting manifestation of small cell carcinoma lung. Oxf Med Case Reports 2015; 2015: 208-10
- 4 Bhargava P, Elble RJ. Clinical reasoning: An unusual cause of transverse myelitis?. Neurology 2014; 82: e46-50
- 5 Sung WS, Sung MJ, Chan JH, Manion B, Song J, Dubey A. et al. Intramedullary spinal cord metastases: A 20-year institutional experience with a comprehensive literature review. World Neurosurg 2013; 79: 576-84
- 6 Nishioka K, Tanaka R, Tsutsumi S, Shimura H, Oji Y, Saeki H. et al. Longitudinally extensive transverse myelitis with intramedullary metastasis of small-cell lung carcinoma: An autopsy case report. Case Rep Neurol Med 2013; 2013: 305670
- 7 Belaid I, Jlassi H, Debbiche G, Rais H, Ben AyedF. Lung adenocarcinoma with intramedullary spinal cord metastasis: A case report and review of the literature. Rev Pneumol Clin 2013; 69: 149-51
- 8 Watanabe M, Nomura T, Sato M, Mochida J. Intramedullary spinal cord metastasis: A clinical and imaging study of seven patients. J Spinal Disord Tech 2006; 19: 43-7
- 9 Ishii T, Terao T, Komine K, Abe T. Intramedullary spinal cord metastases of malignant melanoma: An autopsy case report and review of the literature. Clin Neuropathol 2010; 29: 334-40
- 10 Kannoth S. Paraneoplastic neurologic syndrome: A practical approach. Ann Indian Acad Neurol 2012; 15: 6-12