Nested Stromal and Epithelial Tumor of the Liver: An Unusual Nonhepatocytic Entity

MC Suresh Babu; A Sreevalli; Syed Adil Hassan; G Champaka; D Lokanatha; Linu Abraham Jacob; KN Lokesh; AH Rudresha; LK Rajeev; Saldanha Smitha

doi:10.4103/ijmpo.ijmpo_58_20

Indian Journal of Medical and Paediatric Oncology, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(02): 235-237
DOI: 10.4103/ijmpo.ijmpo_58_20

Grand Round

Nested Stromal and Epithelial Tumor of the Liver: An Unusual Nonhepatocytic Entity

MC Suresh Babu

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

A Sreevalli

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

Syed Adil Hassan

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

G Champaka

Department of Pathology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

D Lokanatha

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

Linu Abraham Jacob

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

KN Lokesh

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

AH Rudresha

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

LK Rajeev

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

,

Saldanha Smitha

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India

References
1 Benedict M, Zhang X. Calcifying nested stromal-epithelial tumor of the liver: An update and literature review. Arch Pathol Lab Med 2019; 143: 264-8
2 Ishak KG, Goodman ZD, Stocker JT. Tumors of the Liver and Intrahepatic Bile Ducts. Ch. 11. Washington, DC: Armed Forces Institute of Pathology; 2001: 276-78
3 Heywood G, Burgart LJ, Nagorney DM. Ossifying malignant mixed epithelial and stromal tumor of the liver: A case report of a previously undescribed tumor. Cancer 2002; 94: 1018-22
4 Grazi GL, Vetrone G, D’Errico A, Caprara G, Ercolani G, Cescon M. et al. Nested stromal-epithelial tumor (NSET) of the liver: A case report of an extremely rare tumor. Pathol Res Pract 2010; 206: 282-6
5 Heerema-McKenney A, Leuschner I, Smith N, Sennesh J, Finegold MJ. Nested stromal epithelial tumor of the liver: Six cases of a distinctive pediatric neoplasm with frequent calcifications and association with cushing syndrome. Am J Surg Pathol 2005; 29: 10-20
6 Makhlouf HR, Abdul-Al HM, Wang G, Goodman ZD. Calcifying nested stromal-epithelial tumors of the liver: A clinicopathologic, immunohistochemical, and molecular genetic study of 9 cases with a long-term follow-up. Am J Surg Pathol 2009; 33: 976-83
7 Wang Y, Zhou J, Huang WB, Rao Q, Ma HH, Zhou XJ. Calcifying nested stroma-epithelial tumor of the liver: A case report and review of literature. Int J Surg Pathol 2011; 19: 268-72
8 Venus A, Mehta SS, Natarajan S. A rare nonhepatocytic primary liver neoplasm with an unusual presentation: Ossifying malignant mixed epithelial and stromal tumor. Indian J Med Paediatric Oncol 2018; 39: 237-40
9 Rod A, Voicu M, Chiche L, Bazille C, Mittre H, Louiset E. et al. Cushing’s syndrome associated with a nested stromal epithelial tumor of the liver: Hormonal, immunohistochemical, and molecular studies. Eur J Endocrinol 2009; 161: 805-10
10 Khoshnam N, Robinson H, Clay MR, Schaffer LR, Gillespie SE, Shehata BM. Calcifying nested stromal-epithelial tumor (CNSET) of the liver in Beckwith-Wiedemann syndrome. Eur J Med Genet 2017; 60: 136-9
11 Assmann G, Kappler R, Zeindl-Eberhart E, Schmid I, Häberle B, Graeb C. et al. β-Catenin mutations in 2 nested stromal epithelial tumors of the liver – A neoplasia with defective mesenchymal-epithelial transition. Hum Pathol 2012; 43: 1815-27
12 Remes-Troche JM, Montaño-Loza A, Meza-Junco J, García-Leiva J, Torre-Delgadillo A. Hepatoblastoma in adult age. A case report and literature review. Ann Hepatol 2006; 5: 179-81
13 Tsuruta S, Kimura N, Ishido K, Kudo D, Sato K, Endo T. et al. Calcifying nested stromal epithelial tumor of the liver in a patient with Klinefelter syndrome: A case report and review of the literature. World J Surg Oncol 2018; 16: 227
14 Brodsky SV, Sandoval C, Sharma N, Yusuf Y, Facciuto ME, Humphrey M. et al. Recurrent nested stromal epithelial tumor of the liver with extrahepatic metastasis: Case report and review of literature. Pediatr Dev Pathol 2008; 11: 469-73
15 Hommann M, Kaemmerer D, Daffner W, Prasad V, Baum RP, Petrovitch A. et al. Nested stromal epithelial tumor of the liver – Liver transplantation and follow-up. J Gastrointest Cancer 2011; 42: 292-5