Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(01): 72-74
DOI: 10.4103/ijmpo.ijmpo_63_18
Case Reports and Review of Literature

Cervical Hibernoma: A Very Rare Tumor of Childhood – Case Report with Review of Literature

Advait Prakash
Department of Pediatric Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
,
Sangram Singh
Department of Pediatric Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
,
Kshiteej Dhull
Department of General Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
,
Sankalp Sharma
Department of General Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
,
Tanmay Vyas
Department of Pediatric Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
,
Anvesh Jain
Department of Pediatric Surgery, Sri Aurobindo Institute of Medical Sciences and Post Graduate Institute, Indore, Madhya Pradesh, India
› Author Affiliations Financial support and sponsorship Nil.
› Further Information
   Permissions and Reprints

Abstract

Hibernomas are uncommon benign soft-tissue tumors which are composed of brown fat. They are usually seen in adults in the fourth and fifth decades and the common locations are thigh, shoulder, and back. Only few cases in the posterior neck region have been reported in literature. Hibernoma is very uncommon in the pediatric age group and those in the neck region are extremely rare. We present a hibernoma presenting as a swelling on the posterior aspect of base of the neck in a 5-month-old male infant. Considering the rare occurrence in the pediatric age group and difficulty in diagnosis, the clinical features, radiological features, pathological characteristics, differential diagnosis, and management of this rare tumor of childhood are discussed herewith.

Keywords

Brown fat tumor - cervical mass - hibernoma - pediatric neck mas


Publication History

Received: 19 March 2018

Accepted: 21 June 2018

Article published online:
23 May 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Khattala K, Elmadi A, Bouamama H, Rami M, Bouabdallah Y. Cervical hibernoma in a two year old boy. Pan Afr Med J 2013; 16: 27
    CrossrefPubMedGoogle Scholar
  • 2 Grayson JW, Wallace JC. A case report and discussion of hibenomas: Pathology, genetics, diagnosis and treatment. Am J Clin Med 2012; 9: 151-3
    Google Scholar
  • 3 Minni A, Barbaro M, Vitolo D, Filipo R. Hibernoma of the para-glottic space: An unusual tumour of the larynx. Acta Otorhinolaryngol Ital 2008; 28: 141-3
    PubMedGoogle Scholar
  • 4 Nardi CE, Barreto L, Carvalho LV, Guimarães AV. Cervical hibernoma and lipoblastomatosis. Einstein (Sao Paulo) 2013; 11: 111-3
    CrossrefPubMedGoogle Scholar
  • 5 Furlong MA, Fanburg-Smith JC, Miettinen M. The morphologic spectrum of hibernoma: A clinicopathologic study of 170 cases. Am J Surg Pathol 2001; 25: 809-14
    CrossrefPubMedGoogle Scholar
  • 6 Hertoghs M, Van Schil P, Rutsaert R, Van Marck E, Vallaeys J. Intrathoracic hibernoma: Report of two cases. Lung Cancer 2009; 64: 367-70
    CrossrefPubMedGoogle Scholar
  • 7 Della Volpe C, Salazard B, Casanova D, Vacheret H, Bartoli JF, Magalon G. et al. Hibernoma of the antero-lateral thigh. Br J Plast Surg 2005; 58: 859-61
    CrossrefPubMedGoogle Scholar
  • 8 Samayam P, Ramesh AC, Chandra NS, Patil MR, Prasanna DH. Hibernoma at base of neck – A rare case in a six month old infant. IJMPCR 2015; 4: 121-4
    CrossrefGoogle Scholar
  • 9 Boudana D, Wolber A, De Lesalle EM, Delaporte E, Martinot-Duquennoy V. Hibernoma: An uncommon adipocytic tumor. Ann Chir Plast Esthet 2011; 56: 156-9
    CrossrefPubMedGoogle Scholar
  • 10 Peycru T, Tardat E, Schwartz A, Dufau JP, Benois A, Durand-Dastes F. et al. Hibernoma of the neck: A rare benign tumour. Can J Surg 2009; 52: E52-3
    PubMedGoogle Scholar
  • 11 da Motta AC, Tunkel DE, Westra WH, Yousem DM. Imaging findings of a hibernoma of the neck. AJNR Am J Neuroradiol 2006; 27: 1658-9
    PubMedGoogle Scholar
  • 12 Nord KH, Magnusson L, Isaksson M, Nilsson J, Lilljebjörn H, Domanski HA. et al. Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma. Proc Natl Acad Sci U S A 2010; 107: 21122-7
    CrossrefPubMedGoogle Scholar
  • 13 Brodsky JR, Kim DY, Jiang Z. Cervical lipoblastoma: Case report, review of literature, and genetic analysis. Head Neck 2007; 29: 1055-60
    CrossrefPubMedGoogle Scholar
  • 14 López-Ferrer P, Jiménez-Heffernan JA, Yébenes L, Vicandi B, Viguer JM. Fine-needle aspiration cytology of lipoblastoma: A report of two cases. Diagn Cytopathol 2005; 32: 32-4
    CrossrefPubMedGoogle Scholar