Subscribe to RSS
Download PDF
DOI: 10.4103/ijri.IJRI_125_20
111In-Octreoscan SPECT/CT hybrid imaging and 68Ga-DOTANOC PET/CT in neuroendocrine adenoma of the middle ear (NAME)
Financial support and sponsorship Nil.
Abstract
Neuroendocrine adenoma of the middle ear (NAME) represents a rare tumour consisting of an adenoma with mixed neuroendocrine differentiation. A 40-year-old woman was referred to our attention to further investigate the occurrence of a pathological tissue located in the mastoid process of the left temporal bone depicted by head CT and MRI scans. Histopathological examination revealed an epithelial neoplasm with neuroendocrine differentiation features, consistent with the diagnosis of NAME. In order to obtain an accurate differential diagnosis and confirmation of this rare disease, 111In-Octreoscan single photon emission computed tomography (SPECT)/CT and 68Ga-DOTANOC positron emission tomography (PET)/CT were performed, both showing overexpression of somatostatin receptors and thus corroborating the histopathological findings.
Keywords
111In-Octreoscan SPECT - 68Ga-DOTANOC PET/CT - carcinoid - hybrid SPECT/CT imaging - middle ear adenoma - NAME - NETPublication History
Received: 19 March 2020
Accepted: 05 June 2020
Article published online:
19 July 2021
© 2020. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
-
References
- 1 Bittencourt AG, Koji Tsuji R, Cabral FJ, Vilela Pereira L, de Oliveira Fonseca AC, Alves V. et al. Middle ear adenoma with neuroendocrine differentiation: Relate of two cases and literature review. Int Arch Otorhinolaryngol 2013; 17: 340-3
- 2 Tsiouvaka S, Papadopoulou I, Lachanas V, Koltsidopoulo PS, Skoulakis C. Neuroendocrine adenoma of the middle ear presented as paraganglioma: A case report. Hippokratia 2017; 21: 201-3
- 3 Hasan Z, McGinness S, Gunaratne DA, Coleman H, Varikatt W, da Cruz M. Neuroendocrine adenoma of the middle ear: A rare histopathological diagnosis. Case Rep Otolaryngol 2016; 2016: 9834750
- 4 Saliba I, Evrard AS. Middle ear glandular neoplasms: Adenoma, carcinoma or adenoma with neuroendocrine differentiation: A case series. Cases J 2009; 2: 6508
- 5 Hu H, Lim WY, Tan TY, Yuen HW. Neuroendocrine adenoma of middle ear with new bone formation and review of literature. Am J Otolaryngol 2016; 37: 108-11
- 6 Zan E, Limb CJ, Koehler JF, Yousem DM. Middle ear adenoma: A challenging diagnosis. AJNR Am J Neuroradiol 2009; 30: 1602-3
- 7 Fallahi B, Manafi-Farid R, Eftekhari M, Fard-Esfahani A, Emami-Ardekani A, Geramifar P. et al. Diagnostic efficiency of 68Ga-DOTATATE PET/CT as compared to 99mTc-Octreotide SPECT/CT and conventional morphologic modalities in neuroendocrine tumors. Asia Ocean J Nucl Med Biol 2019; 7: 129-40
- 8 Torske KR, Thompson LDR. Adenoma versus carcinoid tumor of the middle ear: A study of 48 cases and review of the literature. Mod Pathol 2002; 15: 543-55
- 9 Frantellizzi V, Pontico M, Letizia C, De Vincentis G. Bladder wall paranganglioma located using123 I-mIBG SPECT and CT imaging. Rev Esp Med Nucl Imagen Mol 2018; 37: 253-4
- 10 Salzman R, Starek I, Ticha V, Skalova A, Kucera J. Metastasizing middle ear carcinoid: An unusual case report, with focus on ultrastructural and immunohistochemical findings. Otol Neurotol 2012; 33: 1418-21