Mucinous cystadenoma of pancreas with honeycombing appearance: Radiological-Pathological correlation

Abstract

Most mucinous cystadenomas of pancreas are solitary and multilocular with a few large compartments. Serous cystadenomas usually have a polycystic or microcystic (honeycomb) pattern consisting of collection of cysts (usually >6) that range from few millimetres up to 2 cm in size. Here we present a case of mucinous cystadenoma of pancreas showing an unusual appearance of honeycombing (which has not been described so far) using imaging studies such as endoscopic ultrasound and computed tomography with histopathological confirmation of the diagnosis.

Keywords

Cystic - honeycombing - Mucinous - pancreatic - tumors

• References

• 1 De Lima J, Javitt M, Mathur S. Residents' teaching files: Mucinous cystic neoplasm of the pancreas. Radiographics 1999; 19: 807-11
• 2 Warshaw AL, Compton CC, Lewandrowski K, Cardenosa G, Mueller PR. Cystic tumors of the pancreas: New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg 1990; 212: 432-43
• 3 Fernández-del Castillo C. Mucinous cystic neoplasms. J Gastrointest Surg 2008; 12: 411-3
• 4 Suzuki M, Fujita N, Onodera H, Kayaba Y, Suzuki S, Kagaya H. et al. Mucinous cystic neoplasm in a young male patient. J Gastroenterol 2005; 40: 1070-4
• 5 Tseng JF. Management of serous cystadenoma of the pancreas. J Gastrointest Surg 2008; 12: 408-10
• 6 Compton CC. Serous cystic tumors of the pancreas. Semin Diagn Pathol 2000; 17: 43-55
• 7 Fukushima N, Fukayama M. Mucinous cystic neoplasms of the pancreas: Pathology and molecular genetics. J Hepatobiliary Pancreat Surg 2007; 14: 238-42
• 8 Allen PJ, Brennan MF. The management of cystic lesions of the pancreas. Adv Surg 2007; 41: 211-28
• 9 Funabiki T, Kamei K. Serous cystadenocarcinoma. In: Pour PM. editors Atlas of Exocrine Pancreatic Tumors. Tokyo: Springer; 1994. p. 101-16
• 10 Sarr MG, Murr M, Smyrk TC, Yeo CJ, Fernandez-Del-Castillo C, Hawes RH. et al. Primary cystic neoplasms of the pancreas: Neoplastic disorders of emerging importance—Current state-of-the-art and unanswered questions. J Gastrointest Surg 2003; 7: 417-28
• 11 Federle MP, McGrath KM. Cystic neoplasms of the pancreas. Gastroenterol Clin North Am 2007; 36: 365-76
• 12 Peijie LV, Mahyoub R, Lin X, Chen K, Chai W, Xie J. Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: A preliminary study. Korean J Radiol 2011; 12: 187-95
• 13 Curry CA, Eng J, Horton KM, Urban B, Siegelman S, Kuszyk BS. et al. Can CT be used for patient triage and treatment?. Am J Roentgenol 2000; 175: 99-103
• 14 Gore R, Wenzke D, Thakrar K, Newmark G, Mehta U, Berlin J. The incidental cystic pancreas mass: A practical approach. Cancer Imaging 2012; 12: 414-21
• 15 Morel A, Marteau V, Chambon E, Gayet B, Zins M. Pancreatic mucinous cystadenoma communicating with the main pancreatic duct on MRI. Br J Radiol 2009; 82: e243-5