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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2020; 03(01): 1-8
DOI: 10.4103/jdep.jdep_13_19
Review Article

Systematic review and meta-analysis estimating the prevalence, burden, and trend of diabetes mellitus in Saudi Arabia

Lukman Owolabi
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
,
Bappa Adamu
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
,
Adamu Imam
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
,
Shakirah Owolabi
1   Department of Medicine/Psychiatry, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria
,
Ibrahim Alhaji
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
,
Mushabab Al-Ghamdi
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
,
Abdullah Alshahrani
Department of Medicine, University of Bisha Medical College, University of Bisha, Bisha, Saudi Arabia
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The aim of this study was to determine, using meta-analysis, the prevalence of diabetes mellitus (DM) and to explore the influence of method of diagnosis, DM types, and study year on the prevalence of DM with the view to evaluating the trend and the burden of DM in KSA. Prevalence estimates were derived using a random effect model on carefully selected population-based studies in KSA. The derived estimates were applied to the total populations in the country to give an estimated burden of DM. Twenty-one studies, with 376,998 participants out of whom 54,837 had DM, were selected. The prevalence of DM was 20.9%, 0.9%, and 12.6% for T2DM, T1DM, and combined T1/T2DM, respectively. Subgroup analysis using the method of DM diagnosis showed that the prevalence of DM was 14.2% (95% confidence interval [CI]: 9.3% to 19.0%) in the fasting plasma glucose group, 6.8% (95% CI: 2.6% to 11%) in oral glucose tolerance group, and 12.5% (6.2%–18.9%) in glycated hemoglobin group. Meta-regression revealed 4.6 × 10−3 increase in prevalence per year. The prevalence of DM in Saudi Arabia is high. There is a rising trend in the prevalence of DM in KSA and it is accompanied by a proportionate increase in the burden of DM.

Keywords

Burden - diabetes mellitus - prevalence - Saudi Arabia - trend

Financial support and sponsorship

Nil.




Publication History

Received: 21 July 2019

Accepted: 27 December 2019

Article published online:
16 June 2022

© 2020. Gulf Association of Endocrinology and Diabetes (GAED). All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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