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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2020; 03(01): 12-14
DOI: 10.4103/jdep.jdep_17_19
Case Report

Insulin autoimmune syndrome (Hirata Disease): Case report in a saudi female patient with graves' disease and literature review

Mohammed Almutairi
Department of Internal Medicine, Security Forces Hospital, Riyadh, Saudi Arabia
,
Hazem Aljumah
Department of Internal Medicine, Security Forces Hospital, Riyadh, Saudi Arabia
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Uncommon scenario of spontaneous hypoglycemia after starting carbimazole due to insulin autoimmune syndrome, characterized by high levels of insulinemia and circulating autoantibodies to insulin without prior insulin administration. So far, in Western countries, <70 cases have been published. In addition, more than 380 cases of this syndrome have been reported.

Keywords

Hirata disease - hypoglycemia - hypoglycemia induce by carbimazole - insulin autoimmune syndrome - insulinoma differential diagnosis - insulinoma mimics

Financial support and sponsorship

Nil.




Publication History

Received: 13 November 2019

Accepted: 02 February 2020

Article published online:
16 June 2022

© 2020. Gulf Association of Endocrinology and Diabetes (GAED). All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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