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CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2021; 04(03): 131-138
DOI: 10.4103/jdep.jdep_17_21
Original Article

Reduction of cardiometabolic risk factors with lifestyle intervention: Randomized controlled trial for efficacy among corporate workers

Abiodun Adelowo
Department of Human Kinetics and Health Education, University of Lagos, Lagos
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Background: Cardiovascular diseases and Type 2 diabetes mellitus are two leading noncommunicable diseases globally. Mitigating their overlapping cardiometabolic risk factors have been identified as vital to the global effort to prevent and control these chronic diseases. Objective: The purpose of the study was to examine the efficacy of lifestyle education intervention on cardiometabolic risk factors. Subjects and Methods: A prospective, placebo-controlled, parallel-group, randomized trial was used to conduct a 12-week lifestyle educational intervention on 184 corporate workers. The collected data were analyzed with analysis of covariance at 0.05 alpha level. Results: The treatment significantly improved the mean difference (all P < 0.05) of the intervention groups' fruits and vegetable consumption (0.64, 95% confidence interval [CI]: 1.03–1.81), physical activity (0.38, 95% CI: 1.22–1.80), and attitude toward healthy living (22.3, 95% CI: 35.56–59.37). It also significantly reduced the mean difference of the participants' salt intake (0.39, 95% CI: 1.44–1.99), daily tobacco use (0.12, 95% CI: 1.70–1.96), alcohol consumption (0.31, 95% CI: 0.37–0.99), resting heart rate (−4.81 bpm, 95% CI: 77.89–84.65), systolic blood pressure (−5.52 mmHg, 95% CI: 117.9–127.61), diastolic blood pressure (−4.41 mmHg, 95% CI: 75.10–81.47), body mass index (−1.78, 95% CI: 24.58–27.65), waist circumference (−0.90 cm, 95% CI: 87.70–91.53), fasting blood glucose (−0.36 mmol/l, 95% CI: 4.84–5.48), total blood cholesterol (0.41 mmol/l, 95% CI: 4.41–5.19), and type 2 diabetes risk scores (−1.76, 95% CI: 5.25–8.86). Conclusion: Lifestyle education is an effective intervention program in reducing the prevalence of cardio-metabolic risk factors among corporate workers.

Keywords

Cardio-metabolic risk factors - cardiovascular diseases - corporate workers - lifestyle intervention - noncommunicable diseases - type 2 diabetes mellitus

Financial support and sponsorship

Nil.




Publication History

Received: 30 April 2021

Accepted: 10 July 2021

Article published online:
06 July 2022

© 2021. Gulf Association of Endocrinology and Diabetes (GAED). All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 World Health Organization. Non-Communicable Diseases Country Profiles 2018. Geneva: World Health Organization; 2018. Available from: https://www.who.int/nmh/publications/ncd-profiles-2018/en/. [Last accessed on 2019 Feb 18].
  • 2 Otgontuya D, Oum S, Buckley BS, Bonita R. Assessment of total cardiovascular risk using WHO/ISH risk prediction charts in three low and middle income countries in Asia. BMC Public Health 2013;13:539.
  • 3 World Heart Federation. Urbanization and Cardiovascular Disease: Raising Heart-Healthy Children in Today's Cities. World Heart Federation; 2012. Available from: https://www.world-heart-federation.org/wp-content/uploads/2017/05/FinalWHFUrbanizationLoResWeb.pdf. [Last acessed on 2017 Apr 02].
  • 4 International Diabetes Federation. IDF Diabetes Atlas Seventh Edition 2015. Available from: http://www.oedg.at/pdf/1606_IDF_Atlas_2015_UK.pdf. [Last accessed on 2018 Mar 21].
  • 5 International Diabetes Federation. IDF Diabetes Atlas Eighth Edition 2017; 2017. Available from: https://diabetesatlas.org/resources/2017-atlas.html. [Last accessed on 2018 Dec 02].
  • 6 Federal Ministry of Health. National Strategic Plan of Action on Prevention and Control of Non-Communicable Diseases. Federal Ministry of Health of Nigeria; 2015. Available from: https://www.medbox.org/Nigeria-national.prevention-and-control.non-communicablediseases.pdf. [Last accessed on 2017 Jun 05].
  • 7 Avendano M, Mackenbach JP. Blood glucose levels: Facing a global crisis. Lancet 2006;368:1631-2.
  • 8 Diabetes United Kingdom. Prediabetes – Preventing the Type 2 Diabetes Epidemic. Diabetes United Kingdom; 2009. Available from: https://www.diabetes.org.uk/Prediabetes-Preventing-Type-2-diabetes-epidemic.pdf. [Last accessed on 2017 Apr 11].
  • 9 Cosentino F, Grant PJ, Aboyans V, Bailey CJ, Ceriello A, Delgado V, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: Full text. Eur Heart J Suppl 2007;9:3-74.
  • 10 Brunzell JD, Davidson M, Furberg CD, Goldberg RB, Howard BV, Stein JH, et al. Lipoprotein management in patients with cardiometabolic risk: Consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation. J Am Coll Cardiol 2008;51:1512-24.
  • 11 Prabhakaran D, Jeemon P, Goenka S, Lakshmy R, Thankappan KR, Ahmed F, et al. Impact of a worksite intervention program on cardiovascular risk factors: A demonstration project in an indian industrial population. J Am Coll Cardiol 2009;53:1718-28.
  • 12 Stoner L, Weatherall M, Skidmore P, Castro N, Lark S, Faulkner J, et al. Cardio-metabolic risk variables in preadolescent children: A factor analysis. Am Heart Assoc 2017;6:e007071.
  • 13 Vanuzzo D, Pilotto L, Mirolo R, Pirelli S. Cardiovascular risk and cardiometabolic risk: An epidemiological evaluation. G Ital Cardiol (Rome) 2008;9:6S-17.
  • 14 World Health Organization. Global Status Report on Non-Communicable Diseases 2010. World Health Organization; 2011. Available from: http://apps.who.int/iris/bitstream/10665/44579/1/9789240686458_eng.pdf. [Last accessed on 2018 Mar 22].
  • 15 Bloom DE, Cafiero ET, Jané-Llopis E, Abrahams-Gessel S, Bloom LR, Fathima S, et al. The Global Economic Burden of Non-Communicable Diseases. World Economic Forum; 2011. Available from: http://www3.weforum.org/docs/WEF_Harvard_HE_GlobalEconomicBurdenNonCommunicableDiseases_2011.pdf. [Last accessed on 2018 Sep 12].
  • 16 Commonwealth Business Council. Non-Communicable Disease: Challenges and Solutions. Commonwealth Business Council; 2011. Available from: https://www.cbcglobal.org/publication/docs/_manual.pdf. [Last accessed on 2018 Oct 15].
  • 17 United Nations. Draft Resolution Submitted by the President of the General Assembly: Political Declaration of the High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases. United Nations; 2011. Available from: https://www.who.int/nmh/events/un_ncd_summit2011/political_declaration_en.pdf. [Last accessed on 2021 Feb 18].
  • 18 Franklin BA, Cushman M. Recent advances in preventive cardiology and lifestyle medicine: A themed series. Circulation 2011;123:2274-83.
  • 19 Wilson PW. Estimation of Cardiovascular Risk in an Individual Patient without Known Cardiovascular Disease. UpToDate; 2017. Available from: http://www.uptodate.com/contents/estimation-of-cardiovascular-risk-in-an-individual-patient-without -knowncardiovascular-disease.pdf. [Last accessed on 2018 Jun 07].
  • 20 Stroke Foundation. Guidelines for the Management of Absolute Cardiovascular Disease Risk. Stroke Foundation; 2012. Available from: https://informme.org.au/Guidelines/Guidelines-for -the-assessment-and-management-of-absolute- CVD-risk. [Last accessed on 2018 Mar 19].
  • 21 Kones R. Is prevention a fantasy, or the future of medicine? A panoramic view of recent data, status, and direction in cardiovascular prevention. Ther Adv Cardiovasc Dis 2011;5:61-81.
  • 22 World Health Organization. Prevention of Cardiovascular Disease: Guidelines for Assessment and Management of Cardiovascular Risk. World Health Organization; 2007. Available from: http://www.who.int/cardiovascular_diseases/guidelines/Full%20text.pdf. [Last accessed on 2020 Jan 04].
  • 23 World Health Organization. Training Manual for Health Workers on Healthy Lifestyle: An Approach for the Prevention and Control of Non-Communicable Diseases. World Health Organization; 2009. Available from: http://www.wpro.who.int/philippines/publications/trainersguide.pdf. [Last accessed on 2018 Sep 11].
  • 24 Groeneveld IF, Proper KI, van der Beek AJ, Hildebrandt VH, van Mechelen W. Lifestyle-focused interventions at the workplace to reduce the risk of cardiovascular disease – A systematic review. Scand J Work Environ Health 2010;36:202-15.
  • 25 Federal Ministry of Health. National Nutritional Guideline on Non-Communicable Disease Prevention, Control and Management. Federal Ministry of Health of Nigeria; 2014. Available from: https://www.health.gov.ng/doc/NutritionalGuideline.pdf. [Last accessed on 2018 Feb 15].
  • 26 Aldana SG. The Culprit and the Cure. Mapleton, UT: Maple Mountain Press; 2005. p. 91-4. Available from: https://www.maplemountainpress.com.
  • 27 Merrill RM, Aldana SG, Greenlaw RL, Diehl HA, Salberg A, Englert H. Can newly acquire healthy behaviors persist? An analysis of health behavior decay. Prev Chronic Dis 2008;5:1-13.
  • 28 McGuire HL, Svetkey LP, Harsha DW, Elmer PJ, Appel LJ, Ard JD. Comprehensive lifestyle modification and blood pressure control: A review of the PREMIER trial. J Clin Hypertens 2004;6:383-90.
  • 29 Rankin P, Morton DP, Diehl H, Gobble J, Morey P, Chang E. Effectiveness of a volunteer-delivered lifestyle modification program for reducing cardiovascular disease risk factors. Am J Cardiol 2012;109:82-6.
  • 30 Yamaoka K, Tango T. Effects of lifestyle modification on metabolic syndrome: A systematic review and meta-analysis. BMC Med 2012;10:138.
  • 31 Van De Rest O, Schutte BA, Deelen J, Stassen SA, van den Akker EB, van Heemst D, et al. Metabolic effects of a 13-weeks lifestyle intervention in older adults: The growing old together study. Aging 2016;8:111-24.
  • 32 World Health Organization. Prevention of Cardiovascular Disease: Guidelines for Assessment and Management of Cardiovascular Risk. World Health Organization; 2007. Available from: http://www.who.int/cardiovascular_diseases/guidelines/Full%20text.pdf. [Last accessed on 2018 Jun 15].
  • 33 Alebiosu OC, Familoni OB, Ogunsemi OO, Raimi TH, Balogun WO, Odusan O, et al. Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian J Endocrinol Metab 2013;17:653-8.
  • 34 Olamoyegun AM, Oluyombo R, Iwuala OS. The performance of the Finnish diabetes risk score (FINDRISC) questionnaire for screening individuals with undiagnosed type 2 diabetes and dysglycaemia in Nigeria. Br J Med Med Res 2017;19:1-8.
  • 35 Khanal MK, Ahmed MS, Moniruzzaman M, Banik PC, Dhungana RR, Bhandari P, et al. Total cardiovascular risk for next 10 years among rural population of Nepal using WHO/ISH risk prediction chart. BMC Res Notes 2017;10:120.