Subscribe to RSS

DOI: 10.4103/wjnm.WJNM_13_20
Isolated aplasia of submandibular salivary gland and contralateral prominence of submandibular and sublingual salivary glands incidentally found on 68Ga-prostate-specific membrane antigen positron emission tomography—computed tomography

Abstract
Prostate-specific membrane antigen (PSMA)-targeted imaging is now an effective tool for the evaluation of prostate cancer patients. Although salivary glands take up 68Ga-PSMA avidly, pathologies of these glands may be readily noticeable. Herein, we present a case of prostate cancer referred for 68Ga-PSMA positron emission tomography—computed tomography in whom an isolated aplasia of the submandibular salivary gland was incidentally found.
Keywords
68Ga-prostate-specific membrane antigen positron emission tomography—computed tomography - isolated aplasia - submandibular salivary glandFinancial support and sponsorship
Nil.
Publication History
Received: 01 May 2020
Accepted: 21 May 2020
Article published online:
19 April 2022
© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Sheikhbahaei S, Werner RA, Solnes LB, Pienta KJ, Pomper MG, Gorin MA, et al. Prostate-specific membrane antigen (PSMA)-targeted PET imaging of prostate cancer: An update on important pitfalls. Semin Nucl Med 2019;49:255-70.
- 2 Farag M, Bolton D, Lawrentschuk N. Prostate-specific membrane antigen for the surgical oncologist: Interpreting expression beyond the prostate. ANZ J Surg 2020;90:715-8.
- 3 Van de Wiele C, Sathekge M, de Spiegeleer B, de Jonghe PJ, Beels L, Maes A. PSMA-targeting positron emission agents for imaging solid tumors other than non-prostate carcinoma: A systematic review. Int J Mol Sci 2019;20:4886.
- 4 Yan Z, Ding N, Liu X, Hua H. Congenital agenesis of all major salivary glands and absence of unilateral lacrimal puncta: A case report and review of the literature. Acta Otolaryngol 2012;132:671-5.
- 5 Srinivasan A, Moyer JS, Mukherji SK. Unilateral submandibular gland aplasia associated with ipsilateral sublingual gland hypertrophy. AJNR Am J Neuroradiol 2006;27:2214-6.
- 6 Kara M, Güçlü O, Dereköy FS, Resorlu M, Adam G. Agenesis of submandibular glands: A report of two cases with review of literature. Case Rep Otolaryngol 2014;2014:569026.
- 7 Ahmed M, Strauss M, Kassaie A, Shotelersuk V, DeGuzman R. Bilateral submandibular gland aplasia with clinico-radiological mass due to prolapsing sublingual salivary tissue through mylohyoid boutonniere: A case report and review. Dentomaxillofac Radiol 2009;38:121-4.
- 8 Jaskoll T, Abichaker G, Witcher D, Sala FG, Bellusci S, Hajihosseini MK, et al. FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis. BMC Dev Biol 2005;5:11.
- 9 Jaskoll T, Witcher D, Toreno L, Bringas P, Moon AM, Melnick M. FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis. Dev Biol 2004;268:457-69.
- 10 Lengana T, Lawal I, Boshomane T, Ololade K, Reyneke F, Kaoma C, et al. Salivary gland activity obscures mandibular metastasis of prostate carcinoma on 68Ga-prostate-specific membrane antigen PET. Clin Nucl Med 2018;43:106-9.