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CC BY-NC-ND 4.0 · World J Nucl Med 2019; 18(01): 63-65
DOI: 10.4103/wjnm.WJNM_5_18
Case Report

Synchronous bilateral renal cell carcinomas in “Asynchrony of metabolism”

Hrushikesh Upendra Aurangabadkar
Department of Nuclear Medicine and PET/CT, Yashoda Hospital, Hyderabad, Telangana, India
,
Lalitha Palle
1   Department of Radiology, Yashoda Hospital, Hyderabad, Telangana, India
,
Zakir Ali
2   Department of Nuclear Medicine and PET/CT, Basavatarakam Indo-American Cancer Hospital, Hyderabad, Telangana, India
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Abstract

Here, we present a case of bilateral synchronous renal cell carcinoma in a 52-year-old male patient, who underwent fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) scan followed by surgical removal of both tumors. On PET scan, left renal mass showed intense FDG uptake while uptake in the right renal mass was minimal. Histopathologically, both tumors were conventional clear cell carcinoma (Fuhrman Grade III). Only the FDG-avid tumor in the left kidney had lymphovascular invasion and necrosis, which are markers of aggressive form of any tumor. FDG PET-CT can act as strong and noninvasive prognostic parameter that could help to identify patients with aggressive disease before treatment.

Keywords

Fuhrman grade - lymphovascular invasion - positron emission tomography - renal cell carcinoma - synchronous primaries

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 00. 00 2019

Angenommen: 00. 00 2019

Artikel online veröffentlicht:
22. April 2022

© 2019. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Klatte T, Wunderlich H, Patard JJ, Kleid MD, Lam JS, Junker K, et al. Clinicopathological features and prognosis of synchronous bilateral renal cell carcinoma: An international multicentre experience. BJU Int 2007;100:21-5.
  • 2 Blute ML, Itano NB, Cheville JC, Weaver AL, Lohse CM, Zincke H, et al. The effect of bilaterality, pathological features and surgical outcome in nonhereditary renal cell carcinoma. J Urol 2003;169:1276-81.
  • 3 Boorjian SA, Crispen PL, Lohse CM, Leibovich BC, Blute ML. The impact of temporal presentation on clinical and pathological outcomes for patients with sporadic bilateral renal masses. Eur Urol 2008;54:855-63.
  • 4 Bertagna F, Motta F, Bertoli M, Bosio G, Fisogni S, Tardanico R, et al. Role of F18-FDG-PET/CT in restaging patients affected by renal carcinoma. Nucl Med Rev Cent East Eur 2013;16:3-8.
  • 5 Katz MD, Serrano MF, Humphrey PA, Grubb RL 3rd, Skolarus TA, Gao F, et al. The role of lymphovascular space invasion in renal cell carcinoma as a prognostic marker of survival after curative resection. Urol Oncol 2011;29:738-44.
  • 6 Higashi K, Ueda Y, Ayabe K, Sakurai A, Seki H, Nambu Y, et al. FDG PET in the evaluation of the aggressiveness of pulmonary adenocarcinoma: Correlation with histopathological features. Nucl Med Commun 2000;21:707-14.
  • 7 Ferda J, Ferdova E, Hora M, Hes O, Finek J, Topolcan O, et al. 18F-FDG-PET/CT in potentially advanced renal cell carcinoma: A role in treatment decisions and prognosis estimation. Anticancer Res 2013;33:2665-72.
  • 8 Namura K, Minamimoto R, Yao M, Makiyama K, Murakami T, Sano F, et al. Impact of maximum standardized uptake value (SUVmax) evaluated by 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG-PET/CT) on survival for patients with advanced renal cell carcinoma: A preliminary report. BMC Cancer 2010;10:667.
  • 9 Frank I, Blute ML, Cheville JC, Lohse CM, Weaver AL, Zincke H, et al. An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score. J Urol 2002;168:2395-400.
  • 10 Sengupta S, Lohse CM, Leibovich BC, Frank I, Thompson RH, Webster WS, et al. Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness. Cancer 2005;104:511-20.