Management of cardiovascular disease in aging persons with haemophilia

Summary

With the aging of the haemophilia population, age related comorbidities become more and more a medical issue. Managing haemophilia patients with cardiovascular disease is a difficult task for many haemophilia-treating physicians. Over the years, insights on prevalence, risk factors and management of cardiovascular disease in haemophilia have improved substantially. It is now recognised that many risk factors, such as hypertension and overweight, occur quite frequently in patients with haemophilia. Several new insights in anticoagulation management of atrial fibrillation and coronary ischaemia in haemophilia have been suggested. This review provides an general overview of the current knowledge of these topics in literature.

Zusammenfassung

Mit zunehmendem Alter werden auch bei Patienten mit Hämophilie altersbedingte Begleitkrankheiten mehr und mehr zum medizinischen Problem. Die Therapie von Hämophilie-Patienten mit einer Herzkreislaufkrankheit ist eine schwierige Aufgabe für die behandelnden Ärzte. Mit den Jahren hat sich das Wissen über Prävalenz, Risikofaktoren und Therapie kardiovaskulärer Krankheiten bei Hämophilie erheblich verbessert. Man weiß heute, dass viele Risikofaktoren wie Hypertonie und Übergewicht recht häufig bei Patienten mit Hämophilie auftreten. Es gibt eine Reihe neuer Ansätze zur Antikoagulationsbehandlung bei Vorhofflimmern und koronarer Ischämie für Hämophilie-Patienten. In dieser Übersichtsarbeit geben wir einen allgemeinen Überblick über den derzeitigen Wissensstand zu diesen Themen in der Literatur.

Keywords

haemophilia - cardiovascular - anticoagulation

Schlüsselwörter

Hämophilie - kardiovaskulär - Antikoagulation

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