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CC BY-NC-ND 4.0 · Sleep Sci 2022; 15(S 01): 49-58
DOI: 10.5935/1984-0063.20200124
ORIGINAL ARTICLES

Association between sleep insufficiency and dyslipidemia: a cross-sectional study among Greek adults in the primary care setting

Autor*innen

  • Dimitrios Tsiptsios

    1   South Tyneside & Sunderland NHS Foundation Trust, Department of Clinical Neurophysiology - Sunderland - Tyne & Wear - United Kingdom.

  • Eleni Leontidou

    2   Democritus University of Thrace, Laboratory of Medical Statistics - Alexandroupolis - Thrace - Greece.

  • Petros N. Fountoulakis

    3   Askepeion Hospital, Department of Cardiology - Athens - Attiki - Greece.

  • Andreas Ouranidis

    4   Aristotle University of Thessaloniki, Department of Pharmaceutics - Thessaloniki - Central Macedonia - Greece.

  • Anestis Matziridis

    2   Democritus University of Thrace, Laboratory of Medical Statistics - Alexandroupolis - Thrace - Greece.

  • Apostolos Manolis

    2   Democritus University of Thrace, Laboratory of Medical Statistics - Alexandroupolis - Thrace - Greece.

  • Andreas S. Triantafyllis

    3   Askepeion Hospital, Department of Cardiology - Athens - Attiki - Greece.

  • Konstantinos Tsamakis

    5   King’s College, Institute of Psychiatry, Psychology and Neuroscience - London - London - United Kingdom.

  • Aspasia Serdari

    6   Democritus University of Thrace, Department of Child and Adolescent Psychiatry - Alexandroupolis - Thrace - Greece.

  • Aikaterini Terzoudi

    7   Democritus University of Thrace, Neurology Department - Alexandroupolis - Thrace - Greece.

  • Elena Dragioti

    8   Linköping University, Department of Health, Medicine and Caring Sciences - Linköping - Linköping - Sweden.

  • Paschalis Steiropoulos

    9   Democritus University of Thrace, Department of Pneumonology - Alexandroupolis - Thrace - Greece.

  • Gregory Tripsianis

    2   Democritus University of Thrace, Laboratory of Medical Statistics - Alexandroupolis - Thrace - Greece.
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Objective To investigate the potential association between sleep insufficiency and dyslipidemia (DL) in the primary care setting using self-reported questionnaires.

Material and Methods 957 adults aged between 19 and 86 years old from the rural area of Thrace, Greece were enrolled in this cross-sectional study. Multistage stratifed cluster sampling was used and the subjects were classifed into three groups according to sleep duration [short (<6h), normal (6-8h), and long (>8h) sleep duration]. DL was defined by a positive response to the question “Have you ever been told by a doctor or health professional that your blood cholesterol or triglyceride levels were high?”, or if they were currently taking antilipidemic agents. Sleep quality, utilizing Epworth sleepiness scale, Athens insomnia scale, Pittsburgh sleep quality index and Berlin questionnaire, was also examined.

Results DL prevalence was significantly associated with short sleep duration (aOR=2.18, p<0.001) and insomnia (aOR=1.43, p=0.050), while its relation with poor sleep quality (aOR=1.31, p=0.094) and risk for obstructive sleep apnea (aOR=1.32, p=0.097) were of marginal statistical significance. Concerning insomnia subtypes, DL was significantly associated with difficulties maintaining sleep (aOR=2.99, p<0.001) and early morning awakenings (aOR=1.38, p=0.050), but not difficulties initiating sleep (aOR=1.18, p=0.328).

Conclusion This study reveals an association between sleep pathology and DL. Thus, early pharmacological and cognitive or behavioral interventions that improve sleep are deemed necessary in order to decrease DL burden.

Cross-Sectional Study - Sleep Duration - Dyslipidemia - Sleep Quality - Insomnia

FUNDING

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-proft sectors.




Publikationsverlauf

Eingereicht: 29. Dezember 2020

Angenommen: 08. März 2021

Artikel online veröffentlicht:
01. Dezember 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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