PDF herunterladen
Open Access
CC BY-NC-ND 4.0 · Sleep Sci 2022; 15(S 01): 229-233
DOI: 10.5935/1984-0063.20210017
SHORT COMMUNICATIONS

Characterization of cyclic alternating pattern in infants with laryngomalacia

Authors

  • Laura Mendoza Cáceres

    1   Universidad Nacional Autónoma de México, Facultad de Medicina, Sleep disorders Clinic - Mexico City - Mexico.

  • Ángel Daniel Santana Vargas

    1   Universidad Nacional Autónoma de México, Facultad de Medicina, Sleep disorders Clinic - Mexico City - Mexico.
    2   General Hospital of Mexico, Department of Research - Mexico City - Mexico.

  • Gabriela Millán Rosas

    1   Universidad Nacional Autónoma de México, Facultad de Medicina, Sleep disorders Clinic - Mexico City - Mexico.

  • Eduardo Barragán Pérez

    3   Hospital Infantil de México Federico Gómez, Pediatric Neurology Department - Mexico City - Mexico.

  • Adrián Poblano

    1   Universidad Nacional Autónoma de México, Facultad de Medicina, Sleep disorders Clinic - Mexico City - Mexico.
    4   National Institute of Rehabilitation, Laboratory of Cognitive Neurophysiology - Mexico City - Mexico.s

  • Rafael Santana Miranda

    1   Universidad Nacional Autónoma de México, Facultad de Medicina, Sleep disorders Clinic - Mexico City - Mexico.
Weitere Informationen
Auch verfügbar auf
  Lizenzen und Reprints
Preview

Objective Cyclic alternanting pattern (CAP) has been considered a marker of sleep instability in children. The aim of this study was to evaluate the CAP in infants with laryngomalacia.

Material and Methods CAP were quantified in 15 infants with laryngomalacia (mean age 167.2±97.21 days) and 10 controls (mean age of 158.5±116.2 days) using polysomnography.

Results The distribution of the A2 subtypes across NREM stages in infants with laryngomalacia showed a decrease, as well as in the mean duration of CAP sequences. The A3 CAP and arousals increased in infants with laryngomalacia. Our data showed a stronger correlation between the mean duration of A1 CAP and the age in healthy controls than in infants with laryngomalacia. In accordance to previous reports infants with laryngomalacia exhibited an increase in total awake time, apnea-hypopnea index, and a decrease in N3 stage compared to controls.

Discussion Our findings add to a growing body of literature of CAP as an indicator of brain maturation

Laryngomalacia - Sleep - Apnea - Infant - Newborn - Diseases


Publikationsverlauf

Eingereicht: 10. August 2020

Angenommen: 08. März 2021

Artikel online veröffentlicht:
01. Dezember 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

 

  • REFERENCES

  • 1 Terzano MG, Mancia D, Salati MR, Costani G, Decembrino A, Parrino L. The cyclic alternating pattern as a physiologic component of normal NREM sleep. Sleep. 1985;8(2):137-45.
  • 2 Santana-Miranda R, Murata C, Bruni O, Rosa A, Alvarado-Ruiz G, Castillo-Montoya CR, et al. Cyclic alternating pattern in infants with congenital hypothyroidism. Brain Dev. 2019 Jan;41(1):66-71.
  • 3 Milano S, Castaldo R, Ferri R, Peraita-Adrados R, Paolino MC, Montesano M, et al. Sleep cyclic alternating pattern analysis in infants with apparent life-threatening events: a daytime polysomnographic study. Clin Neurophysiol. 2012 Jul;123(7):1346-52.
  • 4 Bruni O, Novelli L, Luchetti A, Zarowski M, Meloni M, Cecili M, et al. Reduced NREM sleep instability in benign childhood epilepsy with centro-temporal spikes. Clin Neurophysiol. 2010 Jan;121(5):665-71.
  • 5 Miano S, Bruni O, Elia M, Scifo L, Smerieri A, Trovato A, et al. Sleep phenotypes of intellectual disability: a polysomnographic evaluation in subjects with Down syndrome and Fragile-X syndrome. Clin Neurophysiol. 2008 Apr;119(6):1242-7.
  • 6 Dhamija R, Erickson MK, St Louis EK, Wirrell E, Kotagal S. Sleep abnormalities in children with Dravet syndrome. Pediatr Neurol. 2014;50:474-8.
  • 7 Parrino L, Ferri R, Bruni O, Terzano MG. Cyclic alternationg pattern (CAP): the marker of sleep instability. Sleep Med Rev. 2012 Feb;16(1):27-45.
  • 8 Buchmann A, Ringli M, Kurth S, Schaerer M, Geiger A, Jenni OG. EEG sleep slow-wave activity as a mirror of cortical maturation. Cereb Cortex. 2011 Mar;21(3):607-615.
  • 9 Miano S, Paraita-Adrados R, Montesano M, Castaldo R, Forlani M, Villa MP. Sleep cyclic alternating pattern analysis in healthy children in the first year of life: a daytime polysomnographic analysis. Brain Dev. 2011 May;33(5):421-7.
  • 10 Bedwell J, Zalzal G. Laryngomalacia. Semin Pediatr Surg. 2016 Jun;25(3):119-22.
  • 11 Thompson DM. Abnormal sensorimotor integrative function of the larynx in congenital laryngomalacia: a new theory of etiology. Laryngoscope. 2007 Jun;117(6 Pt 2 Suppl 114):1-33.
  • 12 Miano S, Donfrancesco R, Bruni O, Ferri R, Galiffa S, Pagani J, et al. NREM sleep instability is reduced in children with attention-deficit/ hyperactivity disorder. Sleep. 2006 Jun;29(6):797-803.
  • 13 Bruni O, Ferri R, Novelli L, Finotti E, Terribili M, Troianiello M, et al. Slow EEG amplitude oscillations during NREM sleep and reading disabilities in children with dyslexia. Dev Neuropsychol. 2009 Sep;34(5):539-51.
  • 14 Villamor P, González CT, Álvarez-Neri H. Complete polysomnographic parameters in infants with severe laryngomalacia prior to and after supraglottoplasty. Int J Pediatr Otorhinolaryngol. 2019 Jan;119:131-5.
  • 15 Grigg-Damberger M, Gozal D, Marcus CL, Quan SF, Rosen CL, Chervin RD, et al. The visual scoring of sleep and arousal in infants and children. J Clin Sleep Med. 2007 Mar;3(2):201-40.
  • 16 American Academy of Sleep Medicine (AASM). The AASM manual for the scoring of sleep and associated events. Rules, terminology and technical specifications. Version 2.0. Darien: AASM; 2012.
  • 17 Terzano MG, Parrino L, Sherieri A, Chervin R, Chokroverty S, Guilleminault C, et al. Atlas, rules, and recording techniques for the scoring of cyclic alternating pattern (CAP) in human sleep. Sleep Med. 2001 Nov;2(6):537-53.
  • 18 Tanphaichitr A, Tanphaichitr P, Apiwattanasawee P, Brockbank J, Rutter MJ, Simakajornboon N. Prevalence and risk factors for central sleep apnea in infants with laryngomalacia. Otolaryngol Head Neck Surg. 2014 Apr;150(4):677-83.
  • 19 La Taille JA. Ontogenesis and organization of sleep. Rev Prat. 1989 Jan;39(1):5-9.