Prevalence of Laryngeal Alterations in Patients with Erosive Esophagitis

Summary

Introduction: The association between gastroesophageal reflux disease (GERD) and laryngeal disorders has been much debated in recent years. Recent studies suggest an association between laryngeal symptoms and pharyngeal symptoms extra-esophageal reflux, as atypical presentation of Gastroesophageal Reflux Disease.

Objectives: To correlate the presence of laryngeal to the grades of erosive esophagitis.

Methods: A prospective study. Patients with findings of esophagitis on endoscopy were categorized according to LosAngeles and submitted a questionnaire followed by laryngoscopy. The chi-square test was used for statistical analysis (p < 0.05).

Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 96.6%. Eighteen had changes consistent with class A (60%), class B with seven (7%) and 5 with classes C + D (16.6%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p < 0.05).

Conclusion: The laryngeal disorders are frequent findings in patients with esophagitis, more frequent the greater the degree of esophageal injury.

Resumo

Introdução: A associação entre Doença do Refluxo Gastroesofágico (DRGE) e alterações laríngeas vem sendo muito debatida nos últimos anos. Estudos recentes sugerem associação entre sintomas laríngeos, sintomas faríngeos e refluxo extra-esofágico, como sendo apresentação atípica da Doença do Refluxo Gastroesofágico.

Objetivo: Correlacionar a presença de alterações laríngeas com os graus de esofagite erosiva.

Método: Estudo prospectivo. Os pacientes com achados de esofagite a endoscopia foram classificados de acordo com Los Angeles e submetidos a um questionário seguido de laringoscopia. O teste do qui-quadrado foi utilizado para análise estatística (p < 0,05).

Resultados: Os pacientes com sintomas típicos de refluxo gastroesofágico corresponderam a 96,6%. Dezoito possuíam alterações compatíveis com classe A(60%), 7 com classe B (7%) e 5 com classes C + D (16,6%). A presença de alterações laringoscópicas foi mais prevalente nas esofagites mais severas (classes C e D de Los Angeles) quando comparada aos graus mais leves (classes A e B), diferença estatisticamente significativa (p < 0,05).

Conclusão: As alterações laríngeas são achados frequentes nos pacientes com esofagite, sendo mais prevalentes quanto maior o grau da lesão esofágica.

Keywords

esophagitis - gastroesophageal reflux - laryngitis

Palavras-chave

esofagite - refluxo gastroesofágico - laringite

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