Abstracts (HTML) List of Authors

Kaczmarek, D

Lack of NKp80 expression define a liver-resident CD49a(+) NK cell subset with ILC1-like features

Kaczmarek, DJ

Immunosuppressive effects of bile and bile acids on natural killer cell activity

Kah, J

HDV-GT3 shows similar induction of innate immunity compared to HDV-GT1 in humanized mice despite its high infection efficiency and intrahepatic activity

Kahraman, A

A non-invasive comparison between NASH and Crohn's disease
Improvement of IgG4-associated autoimmune cholangitis in a patient with HCV-cirrhosis by treatment with sofosbuvir and ledipasvir: a case report

Kaiser, R

Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure
Transiente Elastografie (Fibroscan) zur Risikostratifizierung des hepatorenalen Syndroms (HRS)

Kakoschky, B

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Kälsch, J

Ultrasound diagnosis of hepatic steatosis represents increased metabolic risk
Annexin A10 meets the challenge of differentiating intrahepatic cholangiocarcinoma from metastatic pancreatic ductal adenocarcinoma. A comparative study of immunohistochemical markers

Kaminska, D

Biopsy-based analysis of the prosteatotic TM6SF2 p.E167K and PNPLA3 p.I148 M gene variants as potential modifiers of Wilson disease

Karst, U

Role of copper transporter ATP7B in cisplatin resistance in human hepatoma cell lines

Katsounas, A

ERCP in critically ill patients unit is a safe procedure and does not increase mortality
Evaluation eines Faktor XIII-Mangels mittels Rotationsthrombelastometrie (ROTEM®) bei Leberzirrhosepatienten mit Blutungsneigung

Kauertz, K

Evaluation der Serumkonzentration von Osteopontin als diagnostischer und prognostischer Biomarker in Patienten mit cholangiozellulärem Karzinom

Kawala, MA

Generation of a 3D model to better mimic NAFLD in vitro

Kefalakes, H

Clinical outcome and HBsAg variability of hepatitis B virus induced acute liver failure

Keitel, V

The membrane-bound bile acid receptor (TGR5) controls the immune response against Listeria monocytogenes
Protective Role of TGR5 against Portal Hypertension in LCA induced toxic liver damage

Keller, S

Interpretation of follow-up 3D-MRCP/MRI in patients with primary sclerosing cholangitis

Kemming, J

A TCF1 expressing memory-like population of Hepatitis C virus-specific CD8+ T cells is maintained after DAA-mediated viral elimination
Subset diversification of virus-specific CD8+ T-cells in chronic HCV monoinfection and HCV/HIV coinfection
The impact of ERAP1 polymorphisms on virus-specific CD8+ T cell responses in an HLA*B27+ patient with acute hepatitis C virus infection

Kemper, T

Hepatitis B virus production is enhanced through early autophagy, but degraded through autophagosome-lysosome fusion

Kensler, TW

Hepatic Nrf2 overexpression inhibits the deleterious effects induced by c-met deficiency in the progression of NASH

Keskin, H

Ultrasound diagnosis of hepatic steatosis represents increased metabolic risk

Kessler, SM

Hsp72 overexpression protects from liver injury and hepatocellular death via attenuation of oxidative stress and JNK-signaling

Khairnar, V

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8+ T-cell priming and viral control

Khairzada, K

3 Jahre Real-Life Essener Erfahrungen einer Everolimus-basierten Immunsuppression nach Lebertransplantation
Der SNP3099 im mTOR Gen ist prädiktiv für die Verträglichkeit und Wirkung von Everolimus nach Lebertransplantation

Khakoo, SI

HLA-Bw4 80(T) and high HLA-Bw4 copy numbers in combination with KIR3DL1 are associated with superior immune control of HCV infection in people who inject drugs

Khaykin, P

Real-world evidence on all-oral, interferon-free regimens with Ombitasvir/Paritaprevir/r and Dasabuvir for treatment of chronic HCV patients receiving opioid substitution therapy in the German Hepatitis C-Registry

Kickuth, R

Short term effect of transarterial chemoembolization (TACE) on microsomal liver function by means of 13C-methacetin breath test (MBT) in patients with hepatocellular carcinoma (HCC)

Kiemer, AK

Hsp72 overexpression protects from liver injury and hepatocellular death via attenuation of oxidative stress and JNK-signaling

Kinner, S

A non-invasive comparison between NASH and Crohn's disease

Kircher, S

Vitamin D3 improves liver histology and hepatic gene expression in a murine obesity/NASH model independently of intestinal Fgf15 induction

Kirchmeyer, M

Cytokines and hepatocellular carcinoma: Potential progression markers and cell typespecific modulators of the mirnome (Interleukin-6 and JAK/STAT activating cytokines)

Kirchner, G

NOD2 genetic variants confer risk for secondary sclerosing cholangitis in critically ill patients

Kitamura, N

Thyroid Hormone Receptor (TR): a regulator in Liver Fibrogenesis

Klag, T

Cholestasis is associated with induction of antimicrobial active reduced human β-defensin 1

Klein, I

Improved perioperative management using LiMAx test in liver surgery – preliminary results from the randomized Fast-track LiveR trial
Current therapeutical options for hepatocellular carcinoma in a german liver center – initial results of a retrospective data analysis

Klein, S

Novel rat model of repetitive portal venous embolization mimicking human non-cirrhotic idiopathic portal hypertension

Kleinbach, S

Short term effect of transarterial chemoembolization (TACE) on microsomal liver function by means of 13C-methacetin breath test (MBT) in patients with hepatocellular carcinoma (HCC)

Klenerman, P

Sustained Vd1 and Vd2 T-cell profiles in chronic viral hepatitis

Klindt, C

Protective Role of TGR5 against Portal Hypertension in LCA induced toxic liver damage

Klingmüller, U

IL-1β induced activation of the p38MAPK/MK2 pathway in hepatocytes and macrophages: a mathematical model of cell-type-specific signal transduction

Klinker, H

Six weeks of Sofosbuvir/Ledipasvir treatment of acute hepatitis C Virus genotype 1 monoinfection: Final results of the German HepNet Acute HCV IV Study

Kluth, A

ABCB5+ mesenchymal stem cell transplantation in a chronic liver disease mouse model

Kluwe, J

Presence of the MBOAT7 rs641738 variant might enhance liver fibrosis in patients with fatty liver: analysis of the German NAFLD CSG cohort

Knaub, M

Oncogenic transcriptional co-activators YAP and TAZ regulate the expression of MCM helicase constituents in hepatocellular carcinoma

Kneiseler, G

Postmortal diagnosis of hemophagocytic lymphohistiocytosis in a patient with liver failure of unknown etiology

Knolle, P

A TCF1 expressing memory-like population of Hepatitis C virus-specific CD8+ T cells is maintained after DAA-mediated viral elimination

Kobazi Ensari, G

Combined accumulation of hepatitis B surface antigen and mutated alpha-1 antitrypsin promotes the development of liver disease via autophagy overload and activation of p62-mTOR-Nrf2 axis

Köberle, V

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Koch, A

Six weeks of Sofosbuvir/Ledipasvir treatment of acute hepatitis C Virus genotype 1 monoinfection: Final results of the German HepNet Acute HCV IV Study

Koch, B

Macrophage-derived extracellular vesicles mediate a long-lasting innate immune response against hepatitis C virus

Kokordelis, P

Immunosuppressive effects of bile and bile acids on natural killer cell activity

Kollmar, O

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Komorowski, L

Development of autoantibodies against “rings and rods”-associated IMPDH2 in chronic hepatitis C genotype 1 infection during protease inhibitor based triple therapy in a “real life” cohort

König, B

First time use of PRISM, an easy to use and suitable tool to characterize burden of disease, in patients suffering from chronic Hepatitis C: Results from the German observational study LIFE-C
Real-world evidence on all-oral, interferon-free regimens with Ombitasvir/Paritaprevir/r and Dasabuvir for treatment of chronic HCV patients with renal insufficiency in the German Hepatitis C-Registry
Real-world evidence on all-oral, interferon-free regimens with Ombitasvir/Paritaprevir/r and Dasabuvir for treatment of chronic HCV patients receiving opioid substitution therapy in the German Hepatitis C-Registry

Köppel, A

Modulation der Unfolded Protein Response (UPR) im murinen HBV-Modell durch Aktivierung des Transkriptionsfaktors ATF6

Korf, HW

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Korhonen, H

Anti-fibrotic and anti-inflammatory consequences of TGF-β2 silencing in biliary liver disease

Korth, J

Clinical outcome and HBsAg variability of hepatitis B virus induced acute liver failure

Köse, N

A TLR9 promoter polymorphism modulates the monocytic immune responses in decompensated cirrhosis
The regulation of inflammasome components in monocytes and macrophages from patients with decompensated cirrhosis

Kostrzewa, K

Shear wave elastography of the liver and spleen in patients with autoimmune hepatitis and its variants – A single centre study

Kosyakova, N

Verbesserung der Leberfunktion durch mesenchymale Stammzellen im Mausmodell des Alpha-1-Antitrypsinmangels

Koukoulioti, E

Association of Toll-like receptor 4 (TLR4) gene polymorphisms with remission of chronic hepatitis B infections in female patients

Kowarz, E

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Kraft, ARM

Characterization of T cell responses after stopping HBV therapy with nucleos(t)ide analogues (NA) in HBeAg-negative patients

Kramer, C

IL-18, CXCL-8 and CXCL-10 plasma levels decrease in patients with chronic Hepatitis C virus infection undergoing DAA therapy

Krämer, B

Immunosuppressive effects of bile and bile acids on natural killer cell activity
Lack of NKp80 expression define a liver-resident CD49a(+) NK cell subset with ILC1-like features

Kratz, C

Single Nucleotide Polymorphisms (SNPs) im Scarb1 Gen und deren Bedeutung für eine Hepatitis C Virus Infektion

Kraus, MR

First time use of PRISM, an easy to use and suitable tool to characterize burden of disease, in patients suffering from chronic Hepatitis C: Results from the German observational study LIFE-C

Krawczyk, A

Therapeutic Vaccination with a Third Generation PreS/S vaccine (Sci-B-VacTM) with HBV Carriers with Low-level of HBsAg result in Serovonversion to Anti-HBs

Krawczyk, M

Shear wave elastography of the liver and spleen in patients with autoimmune hepatitis and its variants – A single centre study
NOD2 genetic variants confer risk for secondary sclerosing cholangitis in critically ill patients
Extracorporeal blood purification improves nasobiliary drainage (NBD)-refractory pruritus in a BRIC type 2 patient
Biopsy-based analysis of the prosteatotic TM6SF2 p.E167K and PNPLA3 p.I148 M gene variants as potential modifiers of Wilson disease
Presence of the MBOAT7 rs641738 variant might enhance liver fibrosis in patients with fatty liver: analysis of the German NAFLD CSG cohort
Evaluation der pro-steatotischen Genvariante rs641738 im MBOAT7-Gen bei Patienten mit hepatozellulärem Karzinom (HCC)

Krech, T

Inflammation and Fibrosis in the Livers of TNFR1/Mdr2ko Mice

Kreis, S

Cytokines and hepatocellular carcinoma: Potential progression markers and cell typespecific modulators of the mirnome (Interleukin-6 and JAK/STAT activating cytokines)

Kremoser, C

HBV infection alters the transcriptional regulation of FXR-dependent microRNAs

Krenkel, O

Der duale CCR2/CCR5 Antagonist Cenicriviroc reduziert Steatohepatitis und Fibrose durch Inhibition infiltrierender pro-inflammatorischer CCR2+ Monozyten in Mausmodellen der chronischen Leberschädigung

Kronenberger, B

Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Kroy, D

Th2-polarization of CD4+ T-cells is locally induced and drives liver fibrogenesis

Kroy, DC

Hepatic Nrf2 overexpression inhibits the deleterious effects induced by c-met deficiency in the progression of NASH
L-Selectin (CD62L) drives development and progression of non-alcoholic steatohepatitis (NASH) in two dietary mouse models

Kruk, B

Shear wave elastography of the liver and spleen in patients with autoimmune hepatitis and its variants – A single centre study

Kucukoglu, O

Fibrosis in adipose tissue is correlated to liver injury in NAFLD
Elevated release of extracellular vesicles in obese patients with no-alcoholic fatty liver disease (NAFLD)

Kuecuekoktay, FS

Analysis of molecular mechanisms of 5-fluorouracil-induced hepatic steatosis and inflammation in vitro and in mice

Kulawik, A

IL-1β induced activation of the p38MAPK/MK2 pathway in hepatocytes and macrophages: a mathematical model of cell-type-specific signal transduction

Kuna, M

A cholesterol-containing modified western diet inducing steatohepatitis (NASH) with insulin resistance in wildtype B6 mice

Kunst, C

p53 transcription factors control apoptosis susceptibility by regulation of Mcl1
p73 is a potent inducer of IGFBP4 gene expression in hepatocellular carcinoma
IGFBP2 – a novel p53-family target gene in hepatocellular carcinoma
Regulation of p53 – a possible bacterial defense mechanism leading to epithelial barrier destabilization in spontaneous bacterial peritonitis?

Kunz, J

Short term effect of transarterial chemoembolization (TACE) on microsomal liver function by means of 13C-methacetin breath test (MBT) in patients with hepatocellular carcinoma (HCC)

Kunzmann, LK

Increased in vivo and in vitro TH17 differentiation in patients with Primary Sclerosing Cholangitis

Kuo, PC

Thyroid Hormone Receptor (TR): a regulator in Liver Fibrogenesis

Kuscuoglu, D

Combined accumulation of hepatitis B surface antigen and mutated alpha-1 antitrypsin promotes the development of liver disease via autophagy overload and activation of p62-mTOR-Nrf2 axis