Homeopathy 2017; 106(02): 69-78
DOI: 10.1016/j.homp.2017.03.002
Review
Copyright © The Faculty of Homeopathy 2017

Prevalence of homeopathy use by the general population worldwide: a systematic review

Clare Relton
,
Katy Cooper
,
Petter Viksveen
,
Philippa Fibert
,
Kate Thomas
Further Information

Correspondence to:

Clare Relton
School of Health and Related Research (ScHARR)
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
UK

Publication History

Received01 August 2016
revised23 February 2017

accepted09 March 2017

Publication Date:
28 December 2017 (online)

 

Aim: To systematically review surveys of 12-month prevalence of homeopathy use by the general population worldwide.

Methods: Studies were identified via database searches to October 2015. Study quality was assessed using a six-item tool. All estimates were in the context of a survey which also reported prevalence of any complementary and alternative medicine use.

Results: A total of 36 surveys were included. Of these, 67% met four of six quality criteria.

Twelve-month prevalence of treatment by a homeopath was reported in 24 surveys of adults (median 1.5%, range 0.2–8.2%). Estimates for children were similar to those for adults. Rates in the USA, UK, Australia and Canada all ranged from 0.2% to 2.9% and remained stable over the years surveyed (1986–2012).

Twelve-month prevalence of all use of homeopathy (purchase of over-the-counter homeopathic medicines and treatment by a homeopath) was reported in 10 surveys of adults (median 3.9%, range 0.7–9.8%) while a further 11 surveys which did not define the type of homeopathy use reported similar data. Rates in the USA and Australia ranged from 1.7% to 4.4% and remained stable over the years surveyed. The highest use was reported by a survey in Switzerland where homeopathy is covered by mandatory health insurance.

Conclusions: This review summarises 12-month prevalence of homeopathy use from surveys conducted in eleven countries (USA, UK, Australia, Israel, Canada, Switzerland, Norway, Germany, South Korea, Japan and Singapore). Each year a small but significant percentage of these general populations use homeopathy. This includes visits to homeopaths as well as purchase of over-the-counter homeopathic medicines.


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Introduction

The therapeutic system of homeopathy was formulated 200 years ago by the German pharmacist and Samuel Hahnemann.[ 1 ] Hahnemann argued that medicine should follow the principle of similitude (like cures like). Hahnemann developed homeopathy by giving medicinal substances to healthy volunteers and studying the symptoms which they suffered (a process known as a ‘proving’ or a Homeopathic Pathogenetic Trial). Hahnemann then applied the medicinal substances in cases of illness which had similar symptoms. Homeopathic medicines are created from a wide variety of substances (e.g. plants, animals, minerals or chemicals). In order to diminish toxicity, the medicinal substances are diluted successively and shaken vigorously between each dilution step.

There is controversy regarding the provision of homeopathy in state funded healthcare systems, as many claim that the principles on which homeopathy are based are ‘scientifically implausible’.[ 2 ] Despite this, treatment by homeopaths and the provision of homeopathic medicines remain popular, and it is provided and/or subsidized and/or endorsed by a number of governments worldwide, including its provision in a number of publicly funded healthcare systems e.g. India which has an estimated 300,000 practitioners of homeopathy[ 3 ] with homeopathy part of the Indian Ministry of Health,[ 4 ] France where 43.5% of the overall population of healthcare providers prescribe homeopathic medicines (mostly co-prescribed with allopathic medicines) and the UK where homeopathy has been provided by the NHS since its inception in 1948.

This study systematically reviews the data on the prevalence of homeopathy use by the general public worldwide. Our review summarises prevalence data for both treatment by a homeopath and all homeopathy use including purchases of over-the-counter (OTC) homeopathic medicines.


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Methods

Search strategy

The systematic review followed the recommendations in the PRISMA statement.[ 5 ] The following databases were searched in October 2015: MEDLINE via Ovid, Pubmed, Cochrane Database of Systematic Reviews, Allied and Complementary Medicine Database (AMED), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Health Management Information Consortium (HMIC). The search strategy combined terms for: i) complementary and alternative medicines, ii) prevalence, surveys or patterns of use, and iii) population-level or national-level data. The full search strategy is provided in our previous reviews on prevalence of use of any Complementary and Alternative Medicine (CAM).[ 6 ],[ 7 ] The database search was restricted to studies published from 1998 onwards. Studies published prior to 1998 were identified from previous systematic reviews of CAM prevalence.[ 8 ],[ 9 ] Bibliographies of included papers were checked for further relevant studies and experts in the field contacted.


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Inclusion and exclusion criteria

Studies were included if they reported 12-month prevalence of treatment by a homeopath and/or OTC use of homeopathy, in addition to the prevalence of overall CAM use and/or visits to CAM practitioners (the latter were inclusion criteria for the broader review[ 6 ]). Prevalence had to be reported over a 12-month retrospective period within a random or representative general population sample of a nation or a defined geographical area. Surveys of clearly-defined age groups (such as adults, children or older adults) were included. Studies were excluded if they were not based on representative samples of the general population; for example, surveys of sub-populations with specific clinical conditions or socio-demographic characteristics (other than age). Included studies used survey methods such as structured interviews or self-complete questionnaires. Studies were excluded if they did not report 12-month prevalence or were not written in English. Studies were also excluded if the prevalence of CAM use was not expressed as a percentage of the target population (or with data making calculations of percentage possible).


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Study selection and data extraction

Studies identified by the searches were assessed for inclusion by two reviewers. Any ambiguity was discussed between the reviewers. Data were extracted by one reviewer and checked by another. Again, any ambiguity was discussed between reviewers (for example, to discern within each article whether the term ‘homeopathy’ referred to the homeopathic medicines or to visits/consultations with a homeopath).


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Definitions of homeopathy

One challenge in data extraction was understanding what was meant by the term ‘homeopathy’[ 10 ] when surveys asked ‘do you use homeopathy?’. The term ‘homeopathy’ has multiple possible meanings: the therapeutic system of homeopathy, the principles of the therapeutic system of homeopathy, homeopathic medicines (also known as homeopathic remedies), or treatment by a homeopath. We addressed this by reporting estimates of ‘homeopathy use’ in three ways:

  • Treatment by a homeopath: includes survey estimates of one or more ‘visits to’ or ‘consultations with’ a homeopath.

  • All homeopathy use (OTC and treatment by homeopath): includes survey estimates of use of homeopathic medicines purchased OTC and treatment by a homeopath.

  • Homeopathy use (not defined): survey does not define whether estimate refers to treatment by a homeopath or OTC use or both.


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Quality assessment

There is no agreed set of criteria for assessing the quality of health-related surveys. As part of our wider systematic review on prevalence of overall CAM use, we devised a six-item, literature-based quality assessment tool comprising important and assessable criteria of methodological quality.[ 6 ] A revised version of this was applied to each of the included studies.

The criteria covered by the quality assessment tool include: 1) whether homeopathy use was clearly defined as referring to treatment by a homeopath or OTC use or both; 2) whether the survey was piloted (piloting was assumed for government sponsored health surveys); 3) whether the sample size was ≥1000 and/or a sample size calculation was reported; 4) whether the reported response rate was ≥60%; 5) whether data were weighted to population characteristics to reduce non-response bias; and 6) whether a 95% confidence interval and/or standard error were reported for the main prevalence estimates.


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Results

Number of surveys included

The search for surveys on CAM use identified 3147 unique citations. Of these, 3035 were excluded at the title and abstract stage, while the full texts of 112 references were examined. A total of 41 references were included in this review, reporting data from 36 independent surveys conducted in eleven countries (USA, UK, Australia, Israel, Canada, Switzerland, Norway, Germany, South Korea, Japan and Singapore). There were 33 surveys reporting data on adults, 4 reporting data for children and adolescents, and 5 reporting data for older adults. A PRISMA flow-chart for study selection is provided in [Figure 1].

Zoom Image
Figure 1 PRISMA 2009 Flow Diagram e 3147 unique citations. Of these, 3035 were excluded at the title and abstract stage, while the full texts of 112 references were examined.
Table 1

Characteristics and quality assessment of survey reports of homeopathy use

Survey characteristics

Quality criteria

Meets ≥4 quality criteria

Country

Survey type

Year of survey

Name of survey

Reference(s)

1. Homeopathy use defined[*]

2. Piloting of survey reported[]

3. Sample size ≥1000 and/or calculation reported (SSC)

4. Reported response rate ≥60% (adj/unadj/NR)

5. Data weighted to population

6.95% CI and/or SE reported

Adults

USA

Govt. national

2012

NHIS

Clarke (2015)[ 11 ]

Yes

Yes (govt. survey)

Yes (34,525)

Yes 61.2% (NR)

Yes

Yes (SE)

Yes

USA

Govt. national

2007

NHIS

Barnes (2008)[ 12 ]

No

Yes (govt. survey)

Yes

Yes

Yes

Yes (SE)

Yes

18+: 23,393

18+: 67.8% (NR)

0–17: 9417

0–17: 76.5% (NR)

USA

Govt. national

202

NHIS

Barnes (2004)[ 13 ]

No

Yes (govt. survey)

Yes (31,044)

Yes 74.3% (adj)

Yes

Yes (SE)

Yes

USA

Govt. national

1999

NHIS

Ni (2002)[ 14 ]

No

Yes (govt. survey)

Yes (30,801)

Yes 70% (NR)

Yes

Yes (CI)

Yes

USA

Govt. national

1996

MEPS

Druss (1999)[ 15 ]

Yes

Yes (govt. survey)

Yes (Age 18 + 16,068)

Yes 77.7% (NR)

Yes

No (NR)

Yes

USA

Govt. national

1995–6

MIDUS

Honda (2005)[ 16 ]

No

Yes (govt. survey)

Yes (4,242)

Yes 60.8% (NR)

Yes

No (NR)

Yes

USA

Other national

1997

 

Eisenburg (1998)[ 17 ]

Yes

Yes (piloted)

Yes (2055; SSC)

Yes 60% (adj); 49% (unadj)

Yes

Yes (SE)

Yes

USA

Other national

1997

 

Landmark Healthcare (1998)[ 18 ]

No

No (NR)

Yes (1500)

NR

NR

Yes (CI)

No

USA

Other national

1990

 

Eisenberg (1993)[ 19 ]

Yes

Yes (piloted)

Yes (1539; SSC)

Yes 67% (unadj)

Yes

Yes (CI)

Yes

USA

Other sub-nat.

1999

 

Arcury (2004)[ 20 ]

Yes

No (NR)

Yes (1059)

Yes 83.8% (NR)

Yes

Yes (SE)

Yes

UK

Govt. national

2005

HSE

Hunt (2010)[ 21 ]

Yes

Yes (govt. survey)

Yes (7630)

Yes 71% (unadj)

NR

No (NR)

Yes

UK

Govt. national

2001

NOS

Thomas (2004)[ 22 ]

Yes

Yes (govt. survey)

Yes (1794)

Yes 65% (unadj)

NR

Yes (CI)

Yes

UK

Other national

1999

 

Ernst (2000)[ 23 ]

No

No (NR)

Yes (1204)

NR

Yes

No (NR)

No

UK

Other national

1998

 

Thomas (2001)[ 24 ]

Yes

Yes (piloted)

Yes (2669; SSC)

No 59% (adj)

Yes

Yes (CI)

Yes

UK

Other national

1993

 

Thomas (1993)[ 25 ]

Yes

Yes (piloted)

No (676)

Yes 78% (adj)

Yes

Yes (CI)

Yes

UK

Govt. sub-nat.

1986

CHS

Yung (1988)[ 26 ]

Yes

Yes (govt. survey)

Yes (4268)

Yes 70% (adj)

NR

Yes (CI)

Yes

Australia

Other national

2005

 

Xue (2007)[ 27 ]

Yes

Yes (piloted)

Yes (1067; SSC)

NR

Yes

Yes (CI)

Yes

Australia

Govt. sub-nat.

2004

SAHOS

MacLennan (2006)[ 28 ]

Yes

Yes (govt. survey)

Yes (15+: 3015)

Yes 71.7% (unadj)

Yes

Yes (CI)

Yes

Australia

Govt. sub-nat.

2000

SAHOS

MacLennan (2002)[ 29 ]

Yes

Yes (govt. survey)

Yes (3027)

Yes 70.4% (NR)

Yes

Yes (CI)

Yes

Australia

Govt. sub-nat.

1993

SAHOS

MacLennan (1996)[ 30 ]

Yes

Yes (govt. survey)

Yes (3004)

Yes 73.6% (NR)

Yes

No (NR)

Yes

Australia

Other sub-nat.

2012

 

Thomson (2014)[ 31 ]

Yes

Yes (piloted)

Yes (1256)

No 40.3% (NR)

NR

No (NR)

No

Israel

Govt. national

2003–4

INHIS

Niskar (2007)[ 32 ]

Yes

Yes (govt. survey)

Yes (2365)

No 58.6% (unadj)

NR

No (NR)

No

Israel

Other sub-nat.

2000

 

Schmueli (2004a)[ 33 ]

Yes

No (NR)

Yes (2505)

NR

NR

No (NR)

No

Israel

Other sub-nat.

1993

 

Schmueli (2004b)[ 33 ]

Yes

No (NR)

Yes (2003)

NR

NR

No (NR)

No

Canada

Govt. national

2001–5

CCHS

Metcalfe (2010)[ 34 ]

Yes

Yes (govt. survey)

Yes (400,055)

NR

Yes

Yes (CI)

Yes

Canada

Govt. national

1994–5

NPHS

Millar (1997)[ 35 ]

Yes

Yes (govt. survey)

Yes (17,626)

NR

Yes

No (NR)

Yes

Switzerland

Govt. national

2012

SHS

Klein (2015)[ 36 ]

Yes

Yes (govt. survey)

Yes (18,357)

No 45.0% (unadj)

Yes

Yes (CI)

Yes

Switzerland

Govt. national

2007

SHS

Klein (2012)[ 37 ]

Yes

Yes (govt. survey)

Yes (14,432)

No 51.0% (unadj)

Yes

Yes (CI)

Yes

Norway

Other sub-nat.

2008

HUNT 3

Lohre (2012)[ 38 ]

Yes

No (NR)

Yes (50,827)

No 54.0% (unadj)

NR

No (NR)

No

Norway

Other sub-nat.

1995–7

HUNT 2

Steinsbekk (2008)[ 39 ]

Yes

No (NR)

Yes (40,027)

No 43.1% (unadj)

NR

No (NR)

No

Germany

Other sub-nat.

1997–2001

 

Schwarz (2008)[ 40 ]

Yes

No (NR)

Yes (4291)

Yes 68.8% (unadj)

NR

No (NR)

No

South Korea

Other national

2006

 

Ock (2009)[ 41 ]

No

No (NR)

Yes (3000)

No 49.8% (unadj)

Yes

No (NR)

No

Japan

Other national

2001

 

Yamashita (2002)[ 42 ]

No

Yes (piloted)

Yes (1000)

NR

Yes

Yes (CI)

Yes

Children and adolescents

USA

Govt. national

2007

NHIS

Barnes (2008)[ 12 ]

See adults section above

USA

Govt. national

1996

MEPS

Davis (2003), Yussman (2004)[ 43 ],[ 44 ]

Yes

Yes (govt. survey)

Yes (age <18: 6262)

Yes 77.7% (NR)

Yes

Yes (CI)

Yes

Norway

Other sub-nat.

1995–7

HUNT 2

Steinsbekk (2010)[ 45 ]

Yes

No (NR)

Yes (7888)

Yes 79.4% (unadj)

NR

No (NR)

No

Australia

Govt. sub-nat.

2004

SAHOS

Smith (2006)[ 46 ]

No

Yes (govt. survey)

No (age <15: 911)

Yes 71.7% (unadj)

Yes

Yes (CI)

Yes

Older adults

USA

Govt. national

1995–6

MIDUS

Honda (2005), McMahan (2004)[ 16 ],[ 47 ]

See adults section above

USA

Other sub-nat.

1997–8

 

Astin (2000)[ 48 ]

No

No (NR)

No (728)

No 51% (unadj)

NR

No (NR)

No

USA

Other sub-nat.

NR

 

Cheung (2007)[ 49 ]

Yes

Yes (piloted)

Yes (445; SSC)

No 37% (unadj)

NR

No (NR)

No

Singapore

Govt. national

2003–4

NMHSE

Feng (2010)[ 50 ]

Yes

Yes (govt. survey)

Yes (1092)

Yes 72.4% (NR)

Yes

No (NR)

Yes

Australia

Other national

2005

 

Xue (2007), Zhang (2007)[ 27 ],[ 51 ]

See adults section above

* Homeopathy use was considered to be defined if the survey specified that data related to over-the-counter use, treatment by a homeopath, or both.


† Piloting was assumed for government surveys. Abbreviations: adj = adjusted; CCHS = Canadian Community Health Survey; CI = confidence interval; HSE = Health Survey for England; MEPS = Medical Expenditure Panel Survey; MIDUS = Midlife Development in the US; NHIS = National Health Interview Survey; NMHSE = National Mental Health Survey of the Elderly; NOS = National Omnibus Survey; NPHS = National Population Health Survey; NR = not reported; OTC = over-the-counter purchase; SAHOS = South Australian Health Omnibus Survey; SE = standard error; SHS = Swiss Health Survey; SSC = sample size calculation; unadj = unadjusted.



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Quality of included survey reports

Based on the information reported, we assessed all survey reports using six quality criteria ([Table 1]). The quality of survey reports is summarized in [Table 2]. Of the 39 survey reports listed in [Table 1], 26 (67%) of all surveys met at least four of six quality criteria; this was 95% for government sponsored health surveys and 37% for non-government surveys. Around 75% of all surveys defined whether homeopathy use referred to treatment by a homeopath, OTC use or both. A sample size of ≥1000 was achieved in around 90% of all surveys. Government sponsored surveys were more likely than non-government sponsored surveys to report piloting (100% vs. 42%); to achieve a response rate of at least 60% (75% vs. 32%), to weight the data to population characteristics (80% vs. 47%); and to report a confidence interval and/or standard error (65% vs. 42%).


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Prevalence of use of homeopathy

[Table 3] presents the 12-month prevalence of homeopathy use as reported in the included surveys. Survey data are ordered by country, then survey type (government sponsored national, other national, or sub-national), then year of survey. Data are grouped by age: adults; children and adolescents; and older adults. [Table 4] provides a summary of the median and range for prevalence of treatment by homeopaths and all use of homeopathy for each age group.


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Treatment by homeopaths

Adults

Estimates for 12-month prevalence of treatment by a homeopath for adults (24 survey estimates) ranged from 0.2% to 8.2% and the median was 1.5% ([Table 4]).

Table 2

Summary of quality of survey reports

Quality criterion

All survey reports (n = 39) N (%)

Govt. sponsored survey reports (n = 20) N (%)

Other survey reports (n = 19) N (%)

1. Homeopathy use measurement clearly defined[*]

29 (74%)

15 (75%)

14 (74%)

2. Piloting of survey reported (assumed for govt. surveys)

28 (72%)

20 (100%)

8 (42%)

3. Sample size ≥1000 and/or sample size calculation used

36 (92%)

19 (95%)

17 (89%)

4. Reported survey response rate ≥60%

21 (54%)

15 (75%)

6 (32%)

5. Data weighted to population characteristics

25 (64%)

16 (80%)

9 (47%)

6.95% confidence interval and/or standard error reported

21 (54%)

13 (65%)

8 (42%)

Meets ≥4 quality criteria

26 (67%)

19 (95%)

7 (37%)

* Homeopathy use was considered to be defined if the survey specified that data related to over-the-counter use, treatment by a homeopath, or both.


The highest estimates (6.4% and 8.2%) were reported by surveys in Switzerland[ 36 ],[ 37 ] where homeopathy is covered by mandatory health insurance. Estimates from the USA in 1990–1999 ranged from 0.2 to 0.7 (four surveys).[ 15 ],[ 17 ],[ 19 ],[ 20 ] Rates for UK surveys were similar: 0.4–1.9% (five surveys in 1986–2005).[ 21 ],[ 22 ],[ 24 ]–[ 26 ] Rates for Australia were also similar (0.5–2.9%; five surveys in 1993–2012),[ 27 ]–[ 31 ] as were rates for Canada (2.02.3%, two surveys in 1994–2005).[ 34 ],[ 35 ] In most countries, rates remained stable over the years surveyed.


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Children

Estimates of treatment by a homeopath for children and adolescents (2 surveys) were 0.03% in a USA 1996 survey of ages 0–17 years[ 43 ],[ 44 ] and 2.6% in a Norway 1995–7 survey of ages 13–19 years.[ 45 ]


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Older adults

There were no estimates of treatment by a homeopath specifically relating to older adults.


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All homeopathy use (treatment by homeopaths and OTC use)

Adults

Estimates for 12-month prevalence of all homeopathy use by adults (treatment by homeopaths and OTC use) was reported in 10 surveys and ranged from 0.7% to 9.8% with a median of 3.9%. A further 8 surveys did not specify type of homeopathy use; estimates ranged from 0.1% to 5.0% (median 2.1%) ([Table 4]).

The highest prevalence (9.8%) was reported by a 1998 survey in England, which was the only included survey to report separate estimates for treatment by a homeopath (1.2%) and OTC use (8.6%)[ 24 ] ([Table 4]). Two further UK surveys reported rates of 3.1% (all homeopathy use)[ JR ] and 3.5% (use not defined)[ 23 ] ([Table 3]).

Five USA government sponsored health surveys estimated that between 1.7% and 3.1% of the adult population had used homeopathy in the last 12 months.[ 11 ]–[ 14 ],[ 16 ] Rates were similar over the years surveyed (1995–2012). Although homeopathy use was not consistently defined in these USA surveys, the most recent report[ 11 ] specified that estimates covered both treatment by a homeopath and OTC use, so this can probably be assumed for earlier surveys. Rates for Australian government sponsored surveys were similar: 4.4% (1993),[ 30 ] 4.3% (2000)[ 29 ] and 2.2% (2004).[ 28 ] Rates were lower in East Asian countries: Japan (0.3% in 2001)[ 42 ] and South Korea (0.1% in 2006).[ 41 ]


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Older adults

For older adults (3 surveys), estimates of the 12-month prevalence of all homeopathy use were 0.0% in Singapore,[ 50 ] 2.5% in the USA[ 49 ] and 4.6% in Australia[ 27 ],[ 51 ] with a median of 2.5%.


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Children

Two surveys in children reported estimates of 1.3% (USA)[ 12 ] and 2.0% (Australia),[ 46 ] though type of homeopathy use was not defined.


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Discussion

This report provides a comprehensive and systematic review of surveys reporting 12-month prevalence of use of homeopathy. This complements our previous reports which systematically reviewed prevalence of any CAM use and visits to any CAM practitioners,[ 6 ] visits to five specific types of CAM practitioner (acupuncturists, homeopaths, chiropractors, osteopaths and medical herbalists),[ 7 ] and visits to massage therapists.[ 52 ] The data reported here includes estimates from 36 surveys across eleven countries.

Our analysis covers both the prevalence of treatment by a homeopath and also the prevalence of all use of homeopathy (over the counter use or treatment by a homeopath), and all estimates were in the context of a survey or survey subsection relating to health and healthcare which also reported prevalence of any complementary and alternative medicine use. The survey data indicated that the percentage of the adult general population using homeopathy over the previous 12 months was in the range of 0.7–9.8%, with a median estimate of 3.9%, and the percentage accessing treatment by a homeopath over the previous 12 months was in the range of 0.2–8.2%, with a median estimate of 1.5%.

Table 3

Twelve-month prevalence of homeopathy use (treatment by homeopath and all use) by the general population across eleven countries

Survey characteristics

Quality summary

Estimates for prevalence of homeopathy use (%)

Reference(s)

Country

Survey type

Year of survey

Name of survey

Sample size

Sample ages (% males)

Meets ≥4 quality criteria

Defines homeopathy use

Treatment by homeopath

All homeopathy use (treatment by homeopath + OTC)

Homeopathy use (not defined)

Adults [*]

USA

Government national

2012

NHIS

34,525

18+ (NR)

Yes

Yes

2.2

Clarke (2015)[ 11 ]

2007

NHIS

23,393

18+ (NR)

Yes

No

1.8

Barnes (2008)[ 12 ]

2002

NHIS

31,044

18+ (NR)

Yes

No

1.7

Barnes (2004)[ 13 ]

1999

NHIS

30,801

18+ (NR)

Yes

No

3.1

Ni (2002)[ 14 ]

1996

MEPS

16,068

18+ (47)

Yes

Yes

0.4

Druss (1999)[ 15 ]

1995–6

MIDUS

4242

25–74 (43)

Yes

No

2.4

Honda (2005)[ 16 ]

USA

Other national

1997

2055

18+ (48)

Yes

Yes

0.6

3.4

Eisenburg (1998)[ 17 ]

1997

1500

18+ (NR)

No

No

5.0

Landmark (1998)[ 18 ]

1990

1539

18+ (52)

Yes

Yes

0.2

0.7

Eisenberg (1993, 1998)[ 17 ],[ 19 ]

USA

Other sub-national

1999

 

1059

18+ (NR)

Yes

Yes

0.7

Arcury (2004)[ 20 ]

UK

Government national

2005

HSE

7630

16+ (45)

Yes

Yes

1.7

3.1

Hunt (2010)[ 21 ]

2001

NOS

1794

16+ (47)

Yes

Yes

1.9

Thomas (2004)[ 22 ]

UK

Other national

1999

1204

18+ (45)

No

No

3.5

Ernst (2000)[ 23 ]

1998

2669

18+ (43)

Yes

Yes

1.2

9.8

Thomas (2001)[ 24 ]

1993

676

18+ (47)

Yes

Yes

1.7

Thomas (1993)[ 25 ]

UK

Government sub-national

1986

CHS

4268

18+ (NR)

Yes

Yes

0.4

Yung (1988)[ 26 ]

Australia

Other national

2005

 

1067

18+ (49)

Yes

Yes

2.9

6.0

Xue (2007)[ 27 ]

Australia

Government sub-national

2004

SAHOS

3015

15+ (49)

Yes

Yes

0.5

2.2

MacLennan (2006)[ 28 ]

2000

SAHOS

3027

15+ (49)

Yes

Yes

1.2

4.3

MacLennan (2002)[ 29 ]

1993

SAHOS

3004

15+ (49)

Yes

Yes

1.2

4.4

MacLennan (1996)[ 30 ]

Australia

Other sub-national

2012

 

1256

18+ (NR)

No

Yes

2.7

4.3

Thomson (2014)[ 31 ]

Israel

Government national

2003–4

INHIS

2365

21+ (44)

No

Yes

1.3

Niskar (2007)[ 32 ]

Israel

Other sub-national

2000

2505

45–75 (47)

No

Yes

2.8

Shmueli (2004a)[ 33 ]

1993

2003

45–75 (48)

No

Yes

1.8

Shmueli (2004b)[ 33 ]

Canada

Government national

2001–5

CCHS

400,055

12+ (49)

Yes

Yes

2.3

Metcalfe (2010)[ 34 ]

1994–5

NPHS

17,626

15+ (NR)

Yes

Yes

2.0

Millar (1997)[ 35 ]

Switzerland

Government national

2012

SHS

 18,357

15+ (48)

Yes

Yes

8.2

Klein (2015)[ 36 ]

2007

SHS

14,432

15+ (NR)

Yes

Yes

6.4

Klein (2012)[ 37 ]

Norway

Other sub-national

2008

HUNT 3

50,827

20+ (45)

No

Yes

1.3

Lohre (2012)[ 38 ]

1995–7

HUNT 2

40,027

20+ (47)

No

Yes

4.3

Steinsbekk (2008)[ 39 ]

Germany

Other sub-national

1997–01

 

4291

20–79 (49)

No

Yes

1.0

Schwarz (2008)[ 40 ]

South Korea

Other national

2006

 

3000

30–69 (50)

No

No

0.1

Ock (2009)[ 41 ]

Japan

Other national

2001

 

1000

20–79 (49)

Yes

No

0.3

Yamashita (2002)[ 42 ]

Children and adolescents

USA

Government national

2007

NHIS

9417

0–17 (NR)

Yes

No

1.3

Barnes (2008)[ 12 ]

1996

MEPS

6262

0–17 (52)

Yes

Yes

0.03

Davis (2003), Yussman (2004)[ 43 ],[ 44 ]

Norway

Other sub-national

1995–7

HUNT 2

7888

13–19 (NR)

No

Yes

2.6

Steinsbekk (2010)[ 45 ]

Australia

Government sub-national

2004

SAHOS

911

0–15 (46)

Yes

No

2.0

Smith (2006)[ 46 ]

Older adults

USA

Government national

1995–6

MIDUS

335

65–74 (48)

Yes

No

1.5

Honda (2005), McMahan (2004)[ 16 ],[ 47 ]

USA

Other sub-national

1997–8

 

728

65+ (45)

No

No

5.8

Astin (2000)[ 48 ]

NR

445

65–94 (45)

No

Yes

2.5

Cheung (2007)[ 49 ]

Singapore

Government national

2003–4

NMHSE

1092

60+ (44)

Yes

Yes

0.0

Feng (2010)[ 50 ]

Australia

Other national

2005

 

178

65+ (43)

Yes

Yes

4.6

Xue (2007), Zhang (2007)[ 27 ],[ 51 ]

Xue (2007), Zhang (2007)[ 27 ],[ 51 ]

Abbreviations: CCHS = Canadian Community Health Survey; HSE = Health Survey for England; MEPS = Medical Expenditure Panel Survey; MIDUS = Midlife Development in the US; NHIS = National Health Interview Survey; NMHSE = National Mental Health Survey of the Elderly; NOS = National Omnibus Survey; NPHS = National Population Health Survey; OTC = over-the-counter purchase; SAHOS = South Australian Health Omnibus Survey; SHS = Swiss Health Survey.


Data from our previous systematic reviews and our more recent findings suggests that the general public (adult or all ages) of the countries surveyed were similarly likely to consult a homeopath (median 1.5%) as an acupuncturist (median 1.4%), medical herbalist (median 0.9%) or osteopath (median 1.9%), while massage therapists (median 5.5%) and chiropractors (median 7.5%) were visited slightly more often than homeopaths.[ 7 ]

There were various limitations in conducting this literature review. A limitation is that only studies reported in the English language were included, although we included English language reports of surveys from any country. In 10 of 39 reports it was unclear whether a definition of homeopathy was provided to the individuals before participation in the survey. This may have created discrepancies in the data collected. Data was only obtained from surveys which also reported overall 12-month prevalence of any CAM use and/or visits to any CAM practitioner. Therefore, surveys only reporting use of homeopathy but not reporting overall CAM use or visits were not included in this review. This is a potential strength of this review, as data from the types of survey included here (many of which were government sponsored health surveys or large population surveys) may be expected to be of higher quality, and potentially more representative of the general population, than data from surveys of a single therapy.

A number of countries include homeopathy in their publicly funded healthcare systems (UK, France, Italy, Germany, Switzerland, India, Pakistan, Brazil, and Mexico[ 53 ]), yet our review identified estimates from only two of these countries – Switzerland (which has the highest estimate of treatment by a homeopath) and the UK (which had the highest estimate of all homeopathy use). No published English language surveys were identified in India, where homeopathy is a popular treatment modality[ 54 ] and considered part of mainstream medicine. We recommend that a further review is conducted which includes all languages.

Our stringent review methods meant that rigorously conducted single studies which reported homeopathy prevalence data (without CAM prevalence data) were excluded even if they would have met our quality criteria. An example of this is a high quality study of data from the French national health insurance database (SNIIRAM).[ 55 ] This study reported that 10.2% of the overall French population and 18% of children aged 0–4 years in France received at least one prescription for a homeopathic medicine during a 12-month period. Both figures are significantly higher than those found in the studies included in our review.

This review summarises 12-month prevalence of homeopathy use from studies in eleven countries (USA, UK, Australia, Israel, Canada, Switzerland, Norway, Germany, South Korea, Japan and Singapore). Each year a small but significant percentage of these general populations use homeopathy. This includes visits to homeopaths as well as purchase of over-the-counter homeopathic medicines.

Table 4

Summary of twelve-month prevalence of homeopathy use

Age group

Treatment by a homeopath

All homeopathy use (treatment by homeopath + OTC)

Homeopathy use (not defined)

N survey estimates

Median % (range)

N survey estimates

Median % (range)

N survey estimates

Median % (range)

Adults

24

1.5 (0.2–8.2)

10

3.9 (0.7–9.8)

8

2.1 (0.1–5.0)

Children + adolescents

2

1.3 (0.03–2.6)

0

2

1.7 (1.3–2.0)

Older adults

0

3

2.5 (0.0–4.6)

2

3.7 (1.5–5.8)

All age groups[*]

26

1.5 (0.03–8.2)

12

3.3 (0.0–9.8)

11

2.0 (0.1–5.8)

* All age groups excludes “older adults” data for Honda 2005 and Xue 2007 to avoid double-counting as these participants are included within estimates for adults.



#

Funding

None.


#

Author contributions

CR, KT and KC conceived the idea for the review and contributed to the design of the review. All authors contributed to data extraction and compiling of the data, and drafting and critical revision of the manuscript.

Review criteria

Studies were identified via database searches to October 2015. All estimates were in the context of a survey which also reported prevalence of any complementary and alternative medicine use. Studies were excluded if they did not report 12-month prevalence or were not written in English.


#

Message for the clinic

This study systematically reviews what is known about the prevalence of homeopathy use by the general public worldwide. This review highlights that globally there is significant and stable use of treatment by a homeopath and over-the-counter purchase of homeopathic medicines.


#
#

Acknowledgements

Thank you to Phil Harris for co-conceiving the idea for the review, to the reviewers and to University of Sheffield medical students Katherine Beckett and Francesca Onyina for their contribution to the searches.


#
#

Disclosures

We have no conflict of interests.

  • References

  • 1 Hahnemann S. Pure pharmaceutical science: first part. Arnold; Dresden: 1811.
  • 2 The end of homoeopathy. Lancet 2005; 366-9487 690.
  • 3 Manchanda R.K., Kulashreshtha M. Cost effectiveness and efficacy of homeopathy in primary health care units of government of Delhi – a study. In: 60th International Homeopathic Congress, Berlin 2005.
  • 4 National Institute of Homoeopathy, India: Council directive 92/73/EEC of 22 September 1992. No L 297/8, 13/10/1992. Available from: http://www.nih.nic.in/ 2016.
  • 5 Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151 (04) 264-269.
  • 6 Harris P.E., Cooper K.L., Relton C., Thomas K.J. Prevalence of complementary and alternative medicine (CAM) use by the general population: a systematic review and update. Int J Clin Pract 2012; 66 (10) 924-939.
  • 7 Cooper K.L., Harris P.E., Relton C., Thomas K.J. Prevalence of visits to five types of complementary and alternative medicine practitioners by the general population: a systematic review. Complement Ther Clin Pract 2013. http://dx.doi.org/10.1016/j.ctcp.2013.06.006
  • 8 Harris P., Rees R. The prevalence of complementary and alternative medicine use among the general population: a systematic review of the literature. Complement Ther Med 2000; 8 (02) 88-96.
  • 9 Ernst E. Prevalence of use of complementary/alternative medicine: a systematic review. Bull World Health Organ 2000; 78 (02) 252-257.
  • 10 Relton C., O'Cathain A., Thomas K.J. ‘Homeopathy’: untangling the debate. Homeopathy 2008; 97 (03) 152-155.
  • 11 Clarke T.C., Black L.I., Stussman B.J., Barnes P.M., Nahin R.L. Trends in the use of complementary health approaches among adults: United States, 2002–2012. Natl Health Stat Rep 2015; 79: 1-16.
  • 12 Barnes P.M., Bloom B., Nahin R.L. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Rep 2008; 12: 1-23.
  • 13 Barnes P.M., Powell-Griner E., McFann K., Nahin R.L. Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004; 343: 1-19.
  • 14 Ni H., Simile C., Hardy A.M. Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey. Med Care 2002; 40 (04) 353-358.
  • 15 Druss B.G., Rosenheck R.A. Association between use of unconventional therapies and conventional medical services. JAMA 1999; 282 (07) 651-656.
  • 16 Honda K., Jacobson J.S. Use of complementary and alternative medicine among United States adults: the influences of personality, coping strategies, and social support. Prev Med 2005; 40 (01) 46-53.
  • 17 Eisenberg D.M., Davis R.B., Ettner S.L. et al Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 1998; 280 (18) 1569-1575.
  • 18 Landmark Healthcare. The landmark report on public perceptions of alternative care. Sacramento: Landmark Healthcare 1998
  • 19 Eisenberg D.M., Kessler R.C., Foster C., Norlock F.E., Calkins D.R., Delbanco T.L. Unconventional medicine in the United States – prevalence, costs, and patterns of use. N Engl J Med 1993; 328 (04) 246-252.
  • 20 Arcury T.A., Preisser J.S., Gesler W.M., Sherman J.E. Complementary and alternative medicine use among rural residents in Western North Carolina. Complement Health Pract Rev 2004; 9 (02) 93-102.
  • 21 Hunt K.J., Coelho H.F., Wider B. et al Complementary and alternative medicine use in England: results from a national survey. Int J Clin Pract 2010; 64 (11) 1496-1502.
  • 22 Thomas K., Coleman P. Use of complementary or alternative medicine in a general population in Great Britain. Results from the National Omnibus survey. J Public Health 2004; 26 (02) 152-157.
  • 23 Ernst E., White A. The BBC survey of complementary medicine use in the UK. Complement Ther Med 2000; 8 (01) 32-36.
  • 24 Thomas K.J., Nicholl J.P., Coleman P. Use and expenditure on complementary medicine in England: a population based survey. Complement Ther Med 2001; 9 (01) 2-11.
  • 25 Thomas K.J., Fall M., Nicholl J., Williams B. Methodological study to investigate the feasibility of conducting a population-based survey of the use of complementary health care. University of Sheffield; ScHARR: 1993.
  • 26 Yung B., Lewis P., Charny M., Farrow S. Complementary medicine: some population-based data. Complement Med Res 1988; 3 (01) 23-28.
  • 27 Xue C.C., Zhang A.L., Lin V., Da C.C., Story D.F. Complementary and alternative medicine use in Australia: a national population-based survey. J Altern Complement Med 2007; 13 (06) 643-650.
  • 28 MacLennan A.H., Myers S.P., Taylor A.W. The continuing use of complementary and alternative medicine in South Australia: costs and beliefs in 2004. Med J Aust 2006; 184 (01) 27-31.
  • 29 MacLennan A.H., Wilson D.H., Taylor A.W. The escalating cost and prevalence of alternative medicine. Prev Med 2002; 35 (02) 166-173.
  • 30 MacLennan A.H., Wilson D.H., Taylor A.W. Prevalence and cost of alternative medicine in Australia. Lancet 1996; 347 ((9001) 569-573.
  • 31 Thomson P., Jones J., Browne M., Leslie S.J. Psychosocial factors that predict why people use complementary and alternative medicine and continue with its use: a population based study. Complement Ther Clin Pract 2014; 20 (04) 302-310.
  • 32 Niskar A.S., Peled-Leviatan T., Garty-Sandalon N. Who uses complementary and alternative medicine in Israel?. J Altern Complement Med 2007; 13 (09) 989-995.
  • 33 Shmueli A., Shuval J. Use of complementary and alternative medicine in Israel: 2000 vs. 1993. Isr Med Assoc J 2004; 6 (01) 3-8.
  • 34 Metcalfe A., Williams J., McChesney J., Patten S.B., Jette N. Use of complementary and alternative medicine by those with a chronic disease and the general population–results of a national population based survey. BMC Complement Altern Med 2010; 10: 58.
  • 35 Millar W.J. Use of alternative health care practitioners by Canadians. Can J Public Health 1997; 88 (03) 154-158.
  • 36 Klein S.D., Torchetti L., Frei-Erb M., Wolf U. Usage of complementary medicine in Switzerland: results of the Swiss Health Survey 2012 and development since 2007. PLoS One 2015; 10 (10) e0141985.
  • 37 Klein S.D., Frei-Erb M., Wolf U. Usage of complementary medicine across Switzerland: results of the Swiss Health Survey 2007. Swiss Med Wkly 2012; 142: w13666.
  • 38 Lohre A., Rise M.B., Steinsbekk A. Characteristics of visitors to practitioners of homeopathy in a large adult Norwegian population (the HUNT 3 study). Homeopathy 2012; 101 (03) 175-181.
  • 39 Steinsbekk A., Nilsen T.V.L., Rise M.B. Characteristics of visitors to homeopaths in a total adult population study in Norway (HUNT 2). Homeopathy 2008; 97 (04) 178-184.
  • 40 Schwarz S., Messerschmidt H., Volzke H., Hoffmann W., Lucht M., Doren M. Use of complementary medicinal therapies in West Pomerania: a population-based study. Climacteric 2008; 11 (02) 124-134.
  • 41 Ock S.M., Choi J.Y., Cha Y.S. et al The use of complementary and alternative medicine in a general population in South Korea: results from a national survey in 2006. J Korean Med Sci 2009; 24 (01) 1-6.
  • 42 Yamashita H., Tsukayama H., Sugishita C. Popularity of complementary and alternative medicine in Japan: a telephone survey. Complement Ther Med 2002; 10 (02) 84-93.
  • 43 Davis M.P., Darden P.M. Use of complementary and alternative medicine by children in the United States. Arch Pediatr Adolesc Med 2003; 157 (04) 393-396.
  • 44 Yussman S.M., Ryan S.A., Auinger P., Weitzman M. Visits to complementary and alternative medicine providers by children and adolescents in the United States. Ambul Pediatr 2004; 4 (05) 429-435.
  • 45 Steinsbekk A., Steinsbekk A. Families' visits to practitioners of complementary and alternative medicine in a total population (the HUNT studies). Scand J Public Health 2010; 38 (05) 96-104.
  • 46 Smith C., Eckert K. Prevalence of complementary and alternative medicine and use among children in South Australia. J Paediatr Child Health 2006; 42 (09) 538-543.
  • 47 McMahan S., Lutz R. Alternative therapy use among the young-old (ages 65–74): an evaluation of the MIDUS database. J Appl Gerontol 2004; 23 (02) 91-103.
  • 48 Astin J.A., Pelletier K.R., Marie A., Haskell W.L. Complementary and alternative medicine use among elderly persons: one-year analysis of a Blue Shield Medicare supplement. J Gerontol Ser A Biol Sci Med Sci 2000; 55 (01) M4-M9.
  • 49 Cheung C.K., Wyman J.F., Halcon L.L. Use of complementary and alternative therapies in community-dwelling older adults. J Altern Complement Med 2007; 13 (09) 997-1006.
  • 50 Feng L., Chiam P.C., Kua E.H., Ng T.P. Use of complementary and alternative medicines and mental disorders in community-living Asian older adults. Arch Gerontol Geriatrics 2010; 50 (03) 243-249.
  • 51 Zhang A.L., Xue C.C., Lin V., Story D.F. Complementary and alternative medicine use by older Australians. Ann N Y Acad Sci 2007; 1114: 204-215.
  • 52 Harris P.E., Cooper K.L., Relton C., Thomas K.J. Prevalence of visits to massage therapists by the general population: a systematic review. Complement Ther Clin Pract 2014; 20 (01) 16-20.
  • 53 Legal Status of Traditional Medicine and Complementary/Alternative Medicine: A Worldwide Review. Traditional Medicine World Health Organization. http://apps.who.int/medicinedocs/pdf/h2943e/h2943e.pdf.
  • 54 Shrivastava S.R., Shrivastava P.S., Ramasamy J. Mainstreaming of Ayurveda, Yoga, Naturopathy, Unani, Siddha, and Homeopathy with the health care delivery system in India. J Tradit Complement Med 5 (02) 2015; 116-118.
  • 55 Piolot M., Fagot J.P., Riviere S. et al Homeopathy in France in 2011–2012 according to reimbursements in the French national health insurance database (SNIRAM). Fam Pract 2015; 32 (04) 442-448.

Correspondence to:

Clare Relton
School of Health and Related Research (ScHARR)
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
UK

  • References

  • 1 Hahnemann S. Pure pharmaceutical science: first part. Arnold; Dresden: 1811.
  • 2 The end of homoeopathy. Lancet 2005; 366-9487 690.
  • 3 Manchanda R.K., Kulashreshtha M. Cost effectiveness and efficacy of homeopathy in primary health care units of government of Delhi – a study. In: 60th International Homeopathic Congress, Berlin 2005.
  • 4 National Institute of Homoeopathy, India: Council directive 92/73/EEC of 22 September 1992. No L 297/8, 13/10/1992. Available from: http://www.nih.nic.in/ 2016.
  • 5 Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151 (04) 264-269.
  • 6 Harris P.E., Cooper K.L., Relton C., Thomas K.J. Prevalence of complementary and alternative medicine (CAM) use by the general population: a systematic review and update. Int J Clin Pract 2012; 66 (10) 924-939.
  • 7 Cooper K.L., Harris P.E., Relton C., Thomas K.J. Prevalence of visits to five types of complementary and alternative medicine practitioners by the general population: a systematic review. Complement Ther Clin Pract 2013. http://dx.doi.org/10.1016/j.ctcp.2013.06.006
  • 8 Harris P., Rees R. The prevalence of complementary and alternative medicine use among the general population: a systematic review of the literature. Complement Ther Med 2000; 8 (02) 88-96.
  • 9 Ernst E. Prevalence of use of complementary/alternative medicine: a systematic review. Bull World Health Organ 2000; 78 (02) 252-257.
  • 10 Relton C., O'Cathain A., Thomas K.J. ‘Homeopathy’: untangling the debate. Homeopathy 2008; 97 (03) 152-155.
  • 11 Clarke T.C., Black L.I., Stussman B.J., Barnes P.M., Nahin R.L. Trends in the use of complementary health approaches among adults: United States, 2002–2012. Natl Health Stat Rep 2015; 79: 1-16.
  • 12 Barnes P.M., Bloom B., Nahin R.L. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Rep 2008; 12: 1-23.
  • 13 Barnes P.M., Powell-Griner E., McFann K., Nahin R.L. Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004; 343: 1-19.
  • 14 Ni H., Simile C., Hardy A.M. Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey. Med Care 2002; 40 (04) 353-358.
  • 15 Druss B.G., Rosenheck R.A. Association between use of unconventional therapies and conventional medical services. JAMA 1999; 282 (07) 651-656.
  • 16 Honda K., Jacobson J.S. Use of complementary and alternative medicine among United States adults: the influences of personality, coping strategies, and social support. Prev Med 2005; 40 (01) 46-53.
  • 17 Eisenberg D.M., Davis R.B., Ettner S.L. et al Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 1998; 280 (18) 1569-1575.
  • 18 Landmark Healthcare. The landmark report on public perceptions of alternative care. Sacramento: Landmark Healthcare 1998
  • 19 Eisenberg D.M., Kessler R.C., Foster C., Norlock F.E., Calkins D.R., Delbanco T.L. Unconventional medicine in the United States – prevalence, costs, and patterns of use. N Engl J Med 1993; 328 (04) 246-252.
  • 20 Arcury T.A., Preisser J.S., Gesler W.M., Sherman J.E. Complementary and alternative medicine use among rural residents in Western North Carolina. Complement Health Pract Rev 2004; 9 (02) 93-102.
  • 21 Hunt K.J., Coelho H.F., Wider B. et al Complementary and alternative medicine use in England: results from a national survey. Int J Clin Pract 2010; 64 (11) 1496-1502.
  • 22 Thomas K., Coleman P. Use of complementary or alternative medicine in a general population in Great Britain. Results from the National Omnibus survey. J Public Health 2004; 26 (02) 152-157.
  • 23 Ernst E., White A. The BBC survey of complementary medicine use in the UK. Complement Ther Med 2000; 8 (01) 32-36.
  • 24 Thomas K.J., Nicholl J.P., Coleman P. Use and expenditure on complementary medicine in England: a population based survey. Complement Ther Med 2001; 9 (01) 2-11.
  • 25 Thomas K.J., Fall M., Nicholl J., Williams B. Methodological study to investigate the feasibility of conducting a population-based survey of the use of complementary health care. University of Sheffield; ScHARR: 1993.
  • 26 Yung B., Lewis P., Charny M., Farrow S. Complementary medicine: some population-based data. Complement Med Res 1988; 3 (01) 23-28.
  • 27 Xue C.C., Zhang A.L., Lin V., Da C.C., Story D.F. Complementary and alternative medicine use in Australia: a national population-based survey. J Altern Complement Med 2007; 13 (06) 643-650.
  • 28 MacLennan A.H., Myers S.P., Taylor A.W. The continuing use of complementary and alternative medicine in South Australia: costs and beliefs in 2004. Med J Aust 2006; 184 (01) 27-31.
  • 29 MacLennan A.H., Wilson D.H., Taylor A.W. The escalating cost and prevalence of alternative medicine. Prev Med 2002; 35 (02) 166-173.
  • 30 MacLennan A.H., Wilson D.H., Taylor A.W. Prevalence and cost of alternative medicine in Australia. Lancet 1996; 347 ((9001) 569-573.
  • 31 Thomson P., Jones J., Browne M., Leslie S.J. Psychosocial factors that predict why people use complementary and alternative medicine and continue with its use: a population based study. Complement Ther Clin Pract 2014; 20 (04) 302-310.
  • 32 Niskar A.S., Peled-Leviatan T., Garty-Sandalon N. Who uses complementary and alternative medicine in Israel?. J Altern Complement Med 2007; 13 (09) 989-995.
  • 33 Shmueli A., Shuval J. Use of complementary and alternative medicine in Israel: 2000 vs. 1993. Isr Med Assoc J 2004; 6 (01) 3-8.
  • 34 Metcalfe A., Williams J., McChesney J., Patten S.B., Jette N. Use of complementary and alternative medicine by those with a chronic disease and the general population–results of a national population based survey. BMC Complement Altern Med 2010; 10: 58.
  • 35 Millar W.J. Use of alternative health care practitioners by Canadians. Can J Public Health 1997; 88 (03) 154-158.
  • 36 Klein S.D., Torchetti L., Frei-Erb M., Wolf U. Usage of complementary medicine in Switzerland: results of the Swiss Health Survey 2012 and development since 2007. PLoS One 2015; 10 (10) e0141985.
  • 37 Klein S.D., Frei-Erb M., Wolf U. Usage of complementary medicine across Switzerland: results of the Swiss Health Survey 2007. Swiss Med Wkly 2012; 142: w13666.
  • 38 Lohre A., Rise M.B., Steinsbekk A. Characteristics of visitors to practitioners of homeopathy in a large adult Norwegian population (the HUNT 3 study). Homeopathy 2012; 101 (03) 175-181.
  • 39 Steinsbekk A., Nilsen T.V.L., Rise M.B. Characteristics of visitors to homeopaths in a total adult population study in Norway (HUNT 2). Homeopathy 2008; 97 (04) 178-184.
  • 40 Schwarz S., Messerschmidt H., Volzke H., Hoffmann W., Lucht M., Doren M. Use of complementary medicinal therapies in West Pomerania: a population-based study. Climacteric 2008; 11 (02) 124-134.
  • 41 Ock S.M., Choi J.Y., Cha Y.S. et al The use of complementary and alternative medicine in a general population in South Korea: results from a national survey in 2006. J Korean Med Sci 2009; 24 (01) 1-6.
  • 42 Yamashita H., Tsukayama H., Sugishita C. Popularity of complementary and alternative medicine in Japan: a telephone survey. Complement Ther Med 2002; 10 (02) 84-93.
  • 43 Davis M.P., Darden P.M. Use of complementary and alternative medicine by children in the United States. Arch Pediatr Adolesc Med 2003; 157 (04) 393-396.
  • 44 Yussman S.M., Ryan S.A., Auinger P., Weitzman M. Visits to complementary and alternative medicine providers by children and adolescents in the United States. Ambul Pediatr 2004; 4 (05) 429-435.
  • 45 Steinsbekk A., Steinsbekk A. Families' visits to practitioners of complementary and alternative medicine in a total population (the HUNT studies). Scand J Public Health 2010; 38 (05) 96-104.
  • 46 Smith C., Eckert K. Prevalence of complementary and alternative medicine and use among children in South Australia. J Paediatr Child Health 2006; 42 (09) 538-543.
  • 47 McMahan S., Lutz R. Alternative therapy use among the young-old (ages 65–74): an evaluation of the MIDUS database. J Appl Gerontol 2004; 23 (02) 91-103.
  • 48 Astin J.A., Pelletier K.R., Marie A., Haskell W.L. Complementary and alternative medicine use among elderly persons: one-year analysis of a Blue Shield Medicare supplement. J Gerontol Ser A Biol Sci Med Sci 2000; 55 (01) M4-M9.
  • 49 Cheung C.K., Wyman J.F., Halcon L.L. Use of complementary and alternative therapies in community-dwelling older adults. J Altern Complement Med 2007; 13 (09) 997-1006.
  • 50 Feng L., Chiam P.C., Kua E.H., Ng T.P. Use of complementary and alternative medicines and mental disorders in community-living Asian older adults. Arch Gerontol Geriatrics 2010; 50 (03) 243-249.
  • 51 Zhang A.L., Xue C.C., Lin V., Story D.F. Complementary and alternative medicine use by older Australians. Ann N Y Acad Sci 2007; 1114: 204-215.
  • 52 Harris P.E., Cooper K.L., Relton C., Thomas K.J. Prevalence of visits to massage therapists by the general population: a systematic review. Complement Ther Clin Pract 2014; 20 (01) 16-20.
  • 53 Legal Status of Traditional Medicine and Complementary/Alternative Medicine: A Worldwide Review. Traditional Medicine World Health Organization. http://apps.who.int/medicinedocs/pdf/h2943e/h2943e.pdf.
  • 54 Shrivastava S.R., Shrivastava P.S., Ramasamy J. Mainstreaming of Ayurveda, Yoga, Naturopathy, Unani, Siddha, and Homeopathy with the health care delivery system in India. J Tradit Complement Med 5 (02) 2015; 116-118.
  • 55 Piolot M., Fagot J.P., Riviere S. et al Homeopathy in France in 2011–2012 according to reimbursements in the French national health insurance database (SNIRAM). Fam Pract 2015; 32 (04) 442-448.

Zoom Image
Figure 1 PRISMA 2009 Flow Diagram e 3147 unique citations. Of these, 3035 were excluded at the title and abstract stage, while the full texts of 112 references were examined.